NIA IMPACT Collaboratory

October 18, 2022: Richesson to Present on EHR-Based Phenotyping at IMPACT Collaboratory Grand Rounds

Posted on by Damon Seils

Headshot of Rachel RichessonRachel Richesson, cochair of the NIH Pragmatic Trials Collaboratory’s Electronic Health Records (EHR) Core, will present this week at IMPACT Collaboratory Grand Rounds.

The virtual session, “Developing Standards and Quality Metrics for Clinical Phenotyping Using EHR Data in Pragmatic Clinical Trials,” will be held on Thursday, October 20, 2022, at 12:00 pm eastern.

Richesson is a professor of learning health sciences in the University of Michigan School of Medicine. She is working with the EHR Core to develop standards and quality metrics for EHR-based phenotyping, the topic of her upcoming Grand Rounds presentation.

Zoom Details for IMPACT Grand Rounds:

  • Please click the link to join the webinar: https://hebrewseniorlife.zoom.us/j/97344810673
  • Or iPhone one-tap: US: +13126266799,,97344810673#  or +14702509358,,97344810673#
  • Or Telephone: US: +1 312 626 6799  or +1 470 250 9358
  • Webinar ID: 973 4481 0673

September 13, 2022: IMPACT Collaboratory Extends Deadline for NIH Collaboratory Trial Letters of Intent

Posted on by Damon Seils

Logo for the NIA IMPACT CollaboratoryThe deadline to submit letters of intent for the NIA IMPACT NIH Collaboratory Trials Program has been extended to September 30, 2022.

This summer, the IMPACT Collaboratory announced a request for applications for its NIH Collaboratory Trials Program.  This funding mechanism supports large-scale pragmatic clinical trials embedded in healthcare systems to test the effectiveness of nonpharmacological interventions for people living with Alzheimer disease and related dementias and their care partners. The interventions will typically encompass relatively simple system changes or direct patient outreach, or successfully piloted programs ready for testing at scale. Awards are for $500,000 in direct costs for 18 months.

Prospective applicants should email their 1-page letter of intent describing their proposed NIH Collaboratory Trial to IMPACTcollaboratory@hsl.harvard.edu. This information will help determine whether the proposed project aligns with the goals of the request for applications prior to a full application. The goal of these NIH Collaboratory Trials is to generate evidence on effective care delivery practices that can be expanded and/or implemented in other systems.

An informational webinar about the program is available.

More than 5 million Americans are living with Alzheimer disease and related dementias. They are particularly vulnerable to receiving uncoordinated and poor-quality care, which contributes to adverse health outcomes and misuse of resources. The mission of the IMPACT Collaboratory is to advance care for persons with dementia and their caregivers in real-world settings by building national capacity to conduct pragmatic clinical trials that test interventions embedded in healthcare systems.

The NIA IMPACT Collaboratory is supported by a grant from the National Institute on Aging.

August 2, 2022: IMPACT Collaboratory Announces New Funding Opportunities

Posted on by Damon Seils

Logo for the NIA IMPACT CollaboratoryThe NIA IMPACT Collaboratory announced requests for applications for 2 new funding opportunities: the Pilot Grant Program and the NIH Collaboratory Trials Program.  These programs support research and training to increase the nation’s capacity to conduct pragmatic clinical trials of nonpharmacological interventions within healthcare systems to improve care for people living with Alzheimer disease related dementias and their care partners.

The 1-year pilot grant awards will be eligible for funding of up to $175,000. The awards will support pilot projects that aim to generate preliminary data for the design and conduct of full-scale embedded pragmatic clinical trials of nonpharmacologic interventions in healthcare systems for persons living with Alzheimer disease and related dementias and their care partners.

The 2-year NIH Collaboratory Trial awards will be eligible for up to $500,000 for full-scale, Stage IV effectiveness ePCTs (based on the NIH Stage Model) that test, measure, and evaluate the effect of a care delivery intervention program in healthcare systems for people living with Alzheimer disease and related dementias and their care partners.

More than 5 million Americans are living with Alzheimer disease and related dementias. They are particularly vulnerable to receiving uncoordinated and poor-quality care, which contributes to adverse health outcomes and misuse of resources. The mission of the IMPACT Collaboratory is to advance care for persons with dementia and their caregivers in real-world settings by building national capacity to conduct pragmatic clinical trials that test interventions embedded in healthcare systems.

The NIA IMPACT Collaboratory is supported by a grant from the National Institute on Aging.

July 12, 2022: IMPACT Collaboratory to Publish Funding Opportunities for Pilot and NIH Collaboratory Trial Programs

Posted on by Damon Seils

NIA IMPACT Collaboratory logoThe NIA IMPACT Collaboratory will publish new funding opportunities on August 15 for a pilot grants program and a NIH Collaboratory Trials program.

The 1-year pilot grant awards will be eligible for funding of up to $175,000. The awards will support pilot projects that aim to generate preliminary data for the design and conduct of full-scale embedded pragmatic clinical trials of nonpharmacologic interventions in healthcare systems for persons living with Alzheimer disease and related dementias and their care partners.

The 2-year NIH Collaboratory Trial awards will be eligible for up to $500,000 for full-scale, Stage IV effectiveness ePCTs (based on the NIH Stage Model) that test, measure, and evaluate the effect of a care delivery intervention program in healthcare systems for people living with Alzheimer disease and related dementias and their care partners.

More than 5 million Americans are living with Alzheimer disease and related dementias. They are particularly vulnerable to receiving uncoordinated and poor-quality care, which contributes to adverse health outcomes and misuse of resources. The mission of the IMPACT Collaboratory is to advance care for persons with dementia and their caregivers in real-world settings by building national capacity to conduct pragmatic clinical trials that test interventions embedded in healthcare systems.

The NIA IMPACT Collaboratory is supported by a grant from the National Institute on Aging.

June 15, 2022: IMPACT Collaboratory Announces Funding for Career Development Awards

Posted on by Damon Seils

Logo for the NIA IMPACT CollaboratoryThe National Institute on Aging (NIA) Imbedded Pragmatic Alzheimer’s Disease (AD) and AD-Related Dementias (AD/ADRD) Clinical Trials (IMPACT) Collaboratory is now accepting applications for its Career Development Award (CDA) program. These CDAs support the development of MD, PhD, or equivalent researchers who seek careers conducting embedded pragmatic clinical trials (ePCTs) for people living with AD/ADRD and their care partners.

The program will fund 2-year CDAs and will prioritize applications that address dementia care for people of all backgrounds and promote health equity. Each award will provide up to $220,000 in direct costs over 2 years with an indirect cost rate capped at 8%. Awardees are required to devote a minimum of 75% effort toward the goals of the award.

Eligible applicants include MD, PhD, or equivalent researchers who seek careers conducting ePCTs for people living with AD/ADRD and their care partners. Applicants are typically within 7 years of their postdoctoral training program at the time of application. Exceptions will be made in this round of funding for investigators with more than 7 years who can demonstrate evidence of changing their career path to pursue research on ePCTs among people living with dementia. Such applicants must request prior approval.

Applications are due Thursday, September 15, 2022. An informational webinar will be hosted on Wednesday, June 29, at 2:00 PM eastern to provide investigators with an overview of application details. Investigators will have the opportunity to ask questions. Use this link for required preregistration.

Learn more by reading answers to frequently asked questions regarding this award.

February 14, 2022: IMPACT Collaboratory Grand Rounds to Highlight First Decade of NIH Pragmatic Trials Collaboratory

Posted on by Damon Seils
Headshots of Dr. Adrian Hernandez, Dr. Lesley Curtis, and Dr. Kevin Weinfurt
Dr. Adrian Hernandez, Dr. Lesley Curtis, and Dr. Kevin Weinfurt

This week’s NIA IMPACT Collaboratory Grand Rounds session will highlight the first decade of the NIH Pragmatic Trials Collaboratory. The Grand Rounds session—“Lessons From the First Decade of the NIH Pragmatic Trials Collaboratory”—will be held on Thursday, February 17, at 12:00 pm eastern.

The co–principal investigators of the NIH Pragmatic Trials Collaboratory Coordinating Center at Duke University—Drs. Adrian Hernandez, Dr. Lesley Curtis, and Dr. Kevin Weinfurt—will share lessons from the network’s portfolio of NIH Collaboratory Trials and discuss priorities for future research.

The NIA IMPACT Collaboratory is supported by a grant from the National Institute on Aging. Its mission is to advance care for persons with dementia and their caregivers in real-world settings by building national capacity to conduct pragmatic clinical trials that test interventions embedded in healthcare systems.

February 3, 2022: IMPACT Collaboratory Seeks Letters of Intent for Pilot Grants Program

Posted on by Damon Seils

NIA IMPACT Collaboratory logoThe NIA IMPACT Collaboratory is seeking letters of intent from interested applicants for Cycle 4A of its Pilot Grants Program.

The 1-year pilot grant awards will fund up to $175,000 in direct costs for pilot studies that aim to generate preliminary data for full-scale embedded pragmatic clinical trials of nonpharmacologic interventions in healthcare systems for persons living with Alzheimer disease and related dementias and/or their care partners. In this grant cycle, the program will give priority to applications aim that improve care through behavioral economics “nudge” interventions; reduce inequities in healthcare; reduce potentially inappropriate medication use through de-prescribing; or improve care in emergency departments.

The required letters of intent are due by March 4. An optional informational webinar on February 14 will provide an overview of application details and an opportunity to ask questions. More information is available on the IMPACT Collaboratory website.

More than 5 million Americans are living with Alzheimer disease and related dementias. They are particularly vulnerable to receiving uncoordinated and poor-quality care, which contributes to adverse health outcomes and misuse of resources. The mission of the IMPACT Collaboratory is to advance care for persons with dementia and their caregivers in real-world settings by building national capacity to conduct pragmatic clinical trials that test interventions embedded in healthcare systems.

The NIA IMPACT Collaboratory is supported by a grant from the National Institute on Aging.

January 11, 2022: New Funding Opportunities Support Investigators at All Levels in Pragmatic Clinical Research

Posted on by Damon Seils

Logo for the NIA IMPACT CollaboratoryThe NIA IMPACT Collaboratory announced 2 new funding opportunities for researchers at all levels who are interested in pragmatic clinical trials embedded in healthcare systems (ePCTs). They include career development awards for early-stage researchers and a scholars program for midlevel and senior researchers.

  • Career Development Award: The IMPACT Collaboratory will fund 2-year career development awards to support the development of early-stage researchers who are seeking careers conducting ePCTs for people living with Alzheimer disease or related dementias and their care partners. Applications are due March 18. An optional informational webinar will be held on February 1.
  • Health Care System Scholars Program – The IMPACT Collaboratory’s Health Care System Scholars Program offers midlevel and senior investigators an opportunity to develop ePCTs with healthcare systems interested in improving the care provided to people living with Alzheimer disease or related dementias and their care partners. Letters of intent are due February 8. An optional informational webinar will be held on January 20.

The NIA IMPACT Collaboratory is supported by a grant from the National Institute on Aging. Its mission is to advance care for persons with dementia and their caregivers in real-world settings by building national capacity to conduct pragmatic clinical trials that test interventions embedded in healthcare systems.

December 8, 2021: NIH Collaboratory and IMPACT Collaboratory Offer Workshop on Dissemination and Implementation Research and Pragmatic Trials

Posted on by Damon Seils

Logo for AcademyHealthThe NIH Collaboratory is partnering with the IMPACT Collaboratory to offer a pre-conference workshop on December 13 at AcademyHealth’s 14th Annual Conference on the Science of Dissemination and Implementation in Health.

The workshop, Convergence of Dissemination & Implementation Research Methods and Embedded Pragmatic Trials, will provide an introduction to investigative opportunities for pragmatic clinical trials embedded in healthcare systems, along with strategies for conducting clinical trials that provide real-world evidence necessary to inform both practice and policy.

The workshop is being offered free to conference attendees but requires a separate registration. The workshop will provide strategies for integrating implementation research methods in the design and conduct of ePCTs. Speakers will share firsthand experiences and case studies from the NIH Collaboratory and the IMPACT Collaboratory.

The learning objectives of the workshop include:

  • To identify key areas of synergy between ePCTs and implementation research
  • To introduce attendees to the unique characteristics and challenges of designing, conducting, and implementing ePCTs within diverse healthcare systems, and to describe opportunities for integrating implementation research methods into ePCTs
  • To increase the capacity of health services researchers to address important clinical questions with ePCTs and implementation research methods

CONFERENCE DETAILS AND REGISTRATION
14th Annual Conference on the Science of Dissemination and Implementation in Health: Broadening Horizons for Impact: Incorporating Multisectoral Approaches into D&I Science
December 13, 2021

October 11, 2021: IMPACT Collaboratory Issues RFA for New NIH Collaboratory Trials

Posted on by Damon Seils

Logo for the NIA IMPACT CollaboratoryThe IMPACT Collaboratory last week published a request for applications for the second cycle of its NIH Collaboratory Trials Program.

IMPACT will fund up to 2 full-scale embedded pragmatic clinical trials that test, measure, and evaluate the effects of a nonpharmacological care delivery intervention program in a healthcare system for people living with Alzheimer disease and related dementias and their care partners. The goal of the NIH Collaboratory Trials Program is to generate evidence on effective care delivery practices that can be expanded and/or implemented in other systems.

Read the full request for applications.

The IMPACT Collaboratory is supported by a grant from the National Institute on Aging.