January 27, 2026: Workshop Materials Available From ‘Dissemination and Implementation in Embedded Pragmatic Trials: Science-Powered Strategies to Sustain and Spread Effective Interventions’

Logo for the 18th Annual Conference on the Science of Dissemination and Implementation in HealthComplete materials are now available from the NIH Pragmatic Trials Collaboratory’s recent workshop, “Dissemination and Implementation in Embedded Pragmatic Trials: Science-Powered Strategies to Sustain and Spread Effective Interventions.”

The full-day workshop, held on December 14 at AcademyHealth’s 18th Annual Conference on the Science of Dissemination and Implementation in Health, introduced concepts in the design, conduct, and implementation of pragmatic clinical trials embedded in healthcare systems, with a focus on methods relevant to health services researchers. Presenters shared firsthand experiences and case studies from the NIH Collaboratory Trials. The learning objectives of the workshop included:

  • To identify areas of synergy between embedded pragmatic clinical trials and implementation research
  • To introduce participants to the unique characteristics and challenges of designing, conducting, and implementing pragmatic clinical trials embedded in diverse healthcare systems, and describe opportunities for integrating implementation research methods into these trials
  • To increase the capacity of health services researchers to address important clinical questions with embedded pragmatic clinical trials, and share lessons from implementation science for supporting intervention adoption, sustainment, scale-up, and/or deimplementation

Access the complete workshop materials, including slides, speaker biographies, and the full participant guide.

Dissemination and Implementation in Embedded Pragmatic Trials: Science-Powered Strategies to Sustain and Spread Effective Interventions: AcademyHealth (December 2025)

December 14, 2025: The NIH Pragmatic Trials Collaboratory hosted a workshop at AcademyHealth's 18th Annual Conference on the Science of Dissemination and Implementation in Health. The workshop introduced concepts in the design, conduct, and implementation of pragmatic clinical trials embedded in healthcare systems, with a focus on methods relevant to health services researchers.

Agenda and Slides

Morning Sessions

Welcome and Opening Remarks
Emily O'Brien, PhD

Session 1: Embedded Pragmatic Clinical Trials (ePCTs) and Hybrid Effectiveness-Implementation Trials: Similarities and Differences
Hayden Bosworth, PhD

Session 2: Design and Analysis Considerations
Qilu Yu, PhD

Session 3: Measuring Effectiveness and Implementation Outcomes
Angelo Volandes, MD, MPH

Session 4: ePCTs in Context: Small Group Work Followed by Panel Discussion With NIH Collaboratory Trial PIs
Moderator: Emily O'Brien, PhD
*This session includes case study presentations.

Afternoon Sessions

Session 5: Pilot and Feasibility Testing
Lanay Mudd, PhD

Session 6: Ethical and Regulatory Considerations and Posttrial Obligations
Stephanie Morain, PhD, MPH

Session 7: Engaging and Aligning With Health System and Community Partners
Hayden Bosworth, PhD

Session 8: Posttrial Sustainment or Deimplementation of Study Interventions
Vince Mor, PhD

Session 9: ePCTs in Context: Small Group Work Followed by Panel Discussion With NIH Collaboratory Trial PIs
Moderator: Stephanie Morain, PhD, MPH
*This session includes case study presentations.

Session 10: Writing a Compelling Grant Application
Beda Jean-Francois, PhD

Closing Remarks
Beda Jean-Francois, PhD

 

November 4, 2025: NIH Collaboratory to Host Workshop at AcademyHealth Dissemination and Implementation Conference

Logo for the 18th Annual Conference on the Science of Dissemination and Implementation in HealthThe NIH Pragmatic Trials Collaboratory will offer a full-day workshop at the 18th Annual Conference on the Science of Dissemination and Implementation in Health in National Harbor, Maryland. The workshop, “Dissemination & Implementation in Embedded Pragmatic Trials: Science-Powered Strategies to Sustain and Spread Effective Interventions,” will introduce concepts in the design, conduct, and implementation of pragmatic clinical trials embedded in healthcare systems, with a particular focus on methods relevant to health services researchers.

The learning objectives of the workshop include:

  • To identify key areas of synergy between pragmatic trials and implementation research
  • To introduce attendees to the unique characteristics and challenges of designing, conducting, and implementing pragmatic clinical trials embedded within diverse health care systems, and to describe opportunities for integrating implementation research methods into pragmatic trials
  • To increase the capacity of health services researchers to address important clinical questions with embedded pragmatic clinical trials and share lessons from implementation science for supporting intervention adoption, sustainment, scale-up, and/or deimplementation

The theme of this year’s D&I conference is “Realizing the Benefits of Dissemination & Implementation Science.” The annual conference is cohosted by the NIH and AcademyHealth.

WORKSHOP DETAILS AND REGISTRATION
Sunday, December 14, 10:00 am-6:00 pm
Gaylord National, National Harbor, Maryland
Information and registration: https://academyhealth.org/page/2025-di-adjunct-events

September 29, 2025: Registration Opens for Pragmatic Trials Workshop at AcademyHealth–NIH Dissemination & Implementation Conference

Logo for the 18th Annual Conference on the Science of Dissemination and Implementation in HealthThe NIH Pragmatic Trials Collaboratory will offer a full-day workshop at the 18th Annual Conference on the Science of Dissemination and Implementation in Health in National Harbor, Maryland. The workshop, “Dissemination & Implementation in Embedded Pragmatic Trials: Science-Powered Strategies to Sustain and Spread Effective Interventions,” will introduce concepts in the design, conduct, and implementation of pragmatic clinical trials embedded in healthcare systems, with a particular focus on methods relevant to health services researchers.

The learning objectives of the workshop include:

  • To identify key areas of synergy between pragmatic trials and implementation research
  • To introduce attendees to the unique characteristics and challenges of designing, conducting, and implementing pragmatic clinical trials embedded within diverse health care systems, and to describe opportunities for integrating implementation research methods into pragmatic trials
  • To increase the capacity of health services researchers to address important clinical questions with embedded pragmatic clinical trials and share lessons from implementation science for supporting intervention adoption, sustainment, scale-up, and/or deimplementation

The theme of this year’s D&I conference is “Realizing the Benefits of Dissemination & Implementation Science.” The annual conference is cohosted by the NIH and AcademyHealth.

WORKSHOP DETAILS AND REGISTRATION
Sunday, December 14, 10:00 am-6:00 pm
Gaylord National, National Harbor, Maryland
Information and registration: https://academyhealth.org/page/2025-di-adjunct-events

Dissemination and Implementation in Embedded Pragmatic Trials: Getting the Timing Right in Real-World Research: AcademyHealth (December 2024)

A photo from the 2024 AcademyHealth D&I Workshop showing panelists at a dais answering questions from workshop participants.December 8, 2024: The NIH Pragmatic Trials Collaboratory hosted a workshop at AcademyHealth's 17th Annual Conference on the Science of Dissemination and Implementation in Health. The workshop introduced concepts in the design, conduct, and implementation of pragmatic clinical trials embedded in healthcare systems, with a focus on methods relevant to health services researchers.

Agenda and Slides

Morning Sessions

Welcome and Introduction
Emily O'Brien, PhD

Session 1: What Are Embedded Pragmatic Clinical Trials?
Beda Jean-Francois, PhD

Session 2: Trial Objectives and Design: An Overview of Hybrid Designs
Devon Check, PhD

Session 3: Engaging With Health System and Community Partners
Hayden Bosworth, PhD

Session 4: ePCTs in Context: Small Group Work and Panel Discussion With NIH Collaboratory Trial Investigators
Moderator: Angelo Volandes, MD, MPH
*This session includes case study presentations.

Afternoon Sessions

Session 5: Measuring Outcomes
Angelo Volandes, MD, MPH

Session 6: ePCT Design
Jonathan Moyer, PhD

Session 7: ePCT Analysis
Jonathan Moyer, PhD

Session 8: Pilot and Feasibility Testing
Beda Jean-Francois, PhD

Session 9: Ethical and Regulatory Oversight Considerations
Stephanie Morain, PhD, MPH

Session 10: Writing a Compelling Grant Application
Beda Jean-Francois, PhD

Session 11: ePCTs in Context: Small Group Work and Panel Discussion With NIH Collaboratory Trials Investigators
Moderator: Stephanie Morain, PhD, MPH
*This session includes case study presentations.

Closing Remarks
Emily O'Brien, PhD

 

October 22, 2024: Registration Opens for Pragmatic Trials Workshop at AcademyHealth–NIH Dissemination & Implementation Conference

AcademyHealth D&I Conference logoThe NIH Pragmatic Trials Collaboratory will offer a full-day workshop at the 17th Annual Conference on the Science of Dissemination and Implementation in Health in Arlington, Virginia. The workshop, “Dissemination & Implementation in Embedded Pragmatic Trials: Getting the Timing Right in Real-World Research,” will introduce concepts in the design, conduct, and implementation of pragmatic clinical trials embedded in healthcare systems, with a particular focus on methods relevant to health services researchers.

The learning objectives of the workshop include:

  • To identify key areas of synergy between pragmatic trials and implementation research
  • To introduce attendees to the unique characteristics and challenges of designing, conducting, and implementing pragmatic clinical trials embedded within diverse health care systems, and to describe opportunities for integrating implementation research methods into pragmatic trials
  • To increase the capacity of health services researchers to address important clinical questions with embedded pragmatic clinical trials and share lessons from implementation science for supporting intervention adoption, sustainment, scale-up, and/or deimplementation

The theme of this year’s D&I conference is “Moving Fast and Slow: Optimizing the Pace of Implementation.” The annual conference is cohosted by the NIH and AcademyHealth.

WORKSHOP DETAILS AND REGISTRATION
Sunday, December 8, 10:00 am-6:00 pm
Crystal Gateway Marriott, Arlington, Virginia

October 9, 2023: Registration Opens for Pragmatic Trials Workshop at AcademyHealth Dissemination & Implementation Conference

The NIH Pragmatic Trials Collaboratory will offer a full-day workshop at the 16th Annual Conference on the Science of Dissemination and Implementation in Health in Arlington, Virginia. The workshop, “Dissemination & Implementation in Embedded Pragmatic Trials: Raising the Bar for Real-World Research,” will introduce concepts in the design, conduct, and implementation of pragmatic clinical trials embedded in healthcare systems, with a particular focus on methods relevant to health services researchers.

The learning objectives of the workshop include:

  • To identify key areas of synergy between pragmatic trials and implementation research
  • To introduce attendees to the unique characteristics and challenges of designing, conducting, and implementing pragmatic clinical trials embedded within diverse health care systems, and to describe opportunities for integrating implementation research methods into pragmatic trials
  • To increase the capacity of health services researchers to address important clinical questions with embedded pragmatic clinical trials and share lessons from implementation science for supporting intervention adoption, sustainment, scale-up, and/or deimplementation

The theme of this year’s D&I conference is “Raising Expectations for D&I Science: Challenges and Opportunities.” The annual conference is cohosted by the NIH and AcademyHealth.

WORKSHOP DETAILS AND REGISTRATION
Sunday, December 10, 10:00 am-6:00 pm
Gateway Marriott, Arlington, Virginia

July 12, 2023: Workshop Materials Now Available From ‘Driving Tomorrow’s Outcomes Through Clinical Research in Real-World Settings’

Photo of group discussion at the AcademyHealth WorkshopComplete materials are now available from the NIH Pragmatic Trials Collaboratory’s recent workshop, “Driving Tomorrow’s Outcomes Through Clinical Research in Real-World Settings.

The 2-day workshop, held in June at the 2023 AcademyHealth Annual Research Meeting in Seattle, introduced concepts in the design, conduct, and implementation of pragmatic clinical trials embedded in healthcare systems, with a focus on methods relevant to health services researchers. Presenters shared firsthand experiences and case studies from the NIH Collaboratory Trials.

The learning objectives of the workshop included:

  • To clarify the definition of embedded pragmatic clinical trials and explain their utility.
  • To introduce attendees to the unique characteristics and challenges of designing, conducting, and implementing these trials within diverse healthcare systems.
  • To increase the capacity of health services researchers to address important clinical questions with pragmatic trials in real-world settings, driving tomorrow’s research outcomes.

Access the complete workshop materials, including slides, speaker biographies, and the full participant guide.

May 8, 2023: Pragmatic Trials Workshop Offered at AcademyHealth Conference

Logo for AcademyHealthThe NIH Pragmatic Trials Collaboratory is partnering with AcademyHealth to offer a 1.5-day preconference workshop at the 2023 Annual Research Meeting in Seattle, Washington.

The workshop, “Driving Tomorrow’s Outcomes Through Clinical Research in Real-World Settings,” will cover the essentials of embedded healthcare systems research, along with strategies for conducting clinical trials that provide real-world evidence necessary to inform both practice and policy. Attendees will participate in facilitated, hands-on learning activities and interact with principal investigators of pragmatic clinical trials embedded in healthcare systems, including NIH Collaboratory Trials.

Firsthand experiences and case studies from the NIH Collaboratory will support and illustrate the topics presented and demonstrate how pragmatic trials embedded in real-world settings are driving tomorrow’s outcomes. Speakers will include program officers and senior staff from NIH Institutes, Centers, and Offices and senior investigators from the NIH Collaboratory Trials and the Coordinating Center leadership.

The learning objectives of the workshop include:

  • To clarify the definition of embedded pragmatic clinical trials and explain their utility.
  • To introduce attendees to the unique characteristics and challenges of designing, conducting, and implementing these trials within diverse healthcare systems.
  • To increase the capacity of health services researchers to address important clinical questions with pragmatic trials in real-world settings, driving tomorrow’s research outcomes.

Workshop details and registration
Friday, June 23, 2023, 8:15 a.m.-4:25 p.m.
Saturday, June 24, 2023, 8:00 a.m.-12:00 p.m.
Seattle Convention Center
Seattle, Washington

November 3, 2022: Pragmatic Trials Workshop at 2022 D&I Science Conference Open for Registration

AcademyHealth and NIH logosThe NIH Pragmatic Trials Collaboratory will offer a full-day workshop at the 15th Annual Conference on the Science of Dissemination and Implementation in Health in Washington, DC. The workshop, “Dissemination & Implementation Research Methods and Embedded Pragmatic Trials: Strategies for Designing Studies That Inform Care for Diverse Populations,” will introduce concepts in the design, conduct, and implementation of pragmatic clinical trials embedded in healthcare systems.

The learning objectives of the workshop include:

  • To identify key areas of synergy between pragmatic trials and implementation research
  • To introduce attendees to the unique characteristics and challenges of designing, conducting, and implementing pragmatic clinical trials embedded within diverse health care systems, and to describe opportunities for integrating implementation research methods into pragmatic trials
  • To increase the capacity of health services researchers to address important clinical questions with pragmatic clinical trials and share lessons from implementation science for increasing engagement of diverse participants

The theme of this year’s D&I conference is “(Re)Building Better Systems: Being Proactive, Nimble, and Responsive.” The annual conference is cohosted by the NIH and AcademyHealth.

WORKSHOP DETAILS AND REGISTRATION
Sunday, December 11, 8:00 am-4:45 pm
Walter E. Washington Convention Center, Washington, DC