August 15, 2024: Application Process Opens for HEAL K12 Career Development Award

The Chronic Pain and Fatigue Research Center at the University of Michigan is requesting applications for the HEAL National K12 Clinical Pain Career Development Award (HEAL K12).

The HEAL K12 is a mentored career development program designed to provide protected time for clinicians and scientists to focus on training in and conducting clinical pain research. The award is intended for scholars who may not be ready for a traditional K award or independent R award, come from institutional environments that cannot adequately support the scholar’s career and/or research objectives, and/or are unable to form a mentoring team that would make them competitive for a training or independent research award in clinical pain.

An informational webinar will be held on September 11. Registration is required.

Key Dates

  • Informational Webinar: September 11, 2024
  • Letter of Intent Due Date: October 15, 2024
  • Invitation to Apply: November 5, 2024
  • Full Application Due Date: February 5, 2025
  • Award Announcements: May 1, 2025
  • Program Start Date: June 1, 2025

Additional program information can be found at https://heal-k12.med.umich.edu/. For questions regarding the letter of intent, submission process, or program requirements, or to request a presubmission consultation, email UM-HEALK12@umich.edu.

HEAL K12 is supported by the NIH HEAL Initiative.

February 24, 2023: NIDA Announces Substance Use Prevention Challenge Funding Opportunity

NIDA logoThe National Institute on Drug Abuse (NIDA) invites primary care clinical and research teams to take part in a new Challenge competition funding opportunity, “Substance Use Prevention Services in Primary Care!” With this Challenge, NIDA is seeking better understanding of how primary care providers can implement substance use prevention interventions in their clinical settings.

The Challenge will offer up to four awards of up to $25,000 each. Submissions are due May 19, 2023. Anyone with experience providing primary care services, supporting implementation of evidence-based substance use prevention interventions, researching substance use prevention in primary care, or advocating for substance use prevention in healthcare settings is encouraged to participate.

From the announcement:

The goal of this Challenge is to further research to support for primary care practices identifying people at risk for substance use or misuse and prevent substance use initiation and escalation of misuse to substance use disorders. NIDA recognizes [primary care providers] encounter many challenges to providing substance use prevention services, especially related to time, staffing, knowledge, and payment. We are seeking responses outlining primary care-based substance use prevention models that address risk identification and provision of/referral to substance use prevention interventions. These models should be frameworks that primary care practices could feasibly implement and sustain, and NIDA encourages aspirational and creative responses to introduce new ideas for research and implementation.

Learn more about the Challenge, rules, and submission requirements at Challenge.Gov. Email NIDAChallenge@nih.gov with questions.

February 6, 2023: Postdoctoral Fellowship Available in Ethics and Regulatory Aspects of Pragmatic Trials

Johns Hopkins Berman Institute of Bioethics logoThe Johns Hopkins Berman Institute of Bioethics is accepting applications for its 2023-2024 Postdoctoral Fellowship in the Ethics and Regulatory Aspects of Pragmatic Clinical Trials.

From the announcement:

The Johns Hopkins Berman Institute of Bioethics invites applications for a Postdoctoral Fellowship in the Ethics and Regulatory Aspects of Pragmatic Clinical Trials. This position includes pursuing independent research, working alongside faculty members involved with the ethics and regulatory aspects of large-scale pragmatic clinical trials and participating in the Hecht-Levi Postdoctoral Fellowship in Bioethics.

The postdoctoral fellow is expected to pursue one or more projects addressing the ethics and regulatory aspects of pragmatic clinical trials in collaboration with Berman Institute faculty members. The Fellow will actively engage with the Ethics and Regulatory Cores of the [NIH Pragmatic Trials Collaboratory] and the Pragmatic and Implementation Studies for the Management of Pain to Reduce Opioid Prescribing (PRISM) Resource Coordinating Center.

As a member of the Hecht-Levi cohort of Bioethics Postdoctoral Fellows at the Berman Institute, the Fellow will have access to Berman Institute faculty and resources, including weekly seminars, presentations, discussions with leading academics and policy makers, professional development training, outreach efforts, and teaching opportunities commensurate with experience and background.

Read the full information about the fellowship. Applications will be considered on a rolling basis through April 30, 2023.

January 31, 2023: IMPACT Collaboratory Seeks Letters of Intent for Pilot Grants Program

NIA IMPACT Collaboratory logoThe NIA IMPACT Collaboratory is seeking letters of intent from interested applicants for Cycle 5A of its Pilot Grants Program.

The 1-year pilot grant awards will fund up to $175,000 in direct costs for pilot studies that aim to generate preliminary data for full-scale embedded pragmatic clinical trials of nonpharmacologic interventions in healthcare systems for persons living with Alzheimer disease and related dementias and/or their care partners. In this grant cycle, the program will give priority to applications aim that improve care through behavioral economics “nudge” interventions; reduce inequities in healthcare; reduce potentially inappropriate medication use through de-prescribing; or improve care in emergency departments.

The required letters of intent are due by March 3. An optional informational webinar on February 14 will provide an overview of application details and an opportunity to ask questions. More information is available on the IMPACT Collaboratory website.

More than 5 million Americans are living with Alzheimer disease and related dementias. They are particularly vulnerable to receiving uncoordinated and poor-quality care, which contributes to adverse health outcomes and misuse of resources. The mission of the IMPACT Collaboratory is to advance care for persons with dementia and their caregivers in real-world settings by building national capacity to conduct pragmatic clinical trials that test interventions embedded in healthcare systems.

The NIA IMPACT Collaboratory is supported by a grant from the National Institute on Aging.

October 17, 2022: NINR to Host Webinar for NIH HEAL Initiative Funding Opportunity

NINR logoThe National Institute of Nursing Research (NINR) will host a webinar for its recent request for applications, “RFA-NR-23-001, HEAL Initiative: Prevention and Management of Chronic Pain in Rural Populations (UG3/UH3 Clinical Trial Required).” The webinar will describe key features of the funding opportunity, review the interests of participating Institutes and Centers, and address questions from potential applicants.

The NIH HEAL Initiative℠, or Helping to End Addiction Long-Term Initiative℠, previously announced this new funding opportunity for cooperative research that will accelerate implementation of nonopioid interventions for chronic pain management in rural and remote populations. The initiative will support pragmatic, implementation, and hybrid effectiveness-implementation trials that study strategies for equitably and efficiently implementing effective interventions and evidence-based pain management guidelines in rural and remote communities.

The webinar is optional and not required for application submission. Preregistration is require. Participants are encouraged to submit their questions in advance of the webinar to NINRProgram@nih.gov.

NIH HEAL Prevention and Management of Chronic Pain in Rural Populations Technical Assistance Webinar: RFA-NR-23-001
Date: Monday, October 24, 2022
Time: 12:00-1:00pm ET

Webinar Registration Link:
https://us02web.zoom.us/webinar/register/WN_ajgNL7u3TQy9RnsN3BgM1g

September 20, 2022: Application Period Opens for Postdoctoral Fellowship in Ethics and Regulatory Aspects of Pragmatic Trials

Johns Hopkins Berman Institute of Bioethics logoThe Johns Hopkins Berman Institute of Bioethics this week opened the application period for its 2023-2024 postdoctoral fellowships, including a Postdoctoral Fellowship in the Ethics and Regulatory Aspects of Pragmatic Clinical Trials.

From the announcement:

The Johns Hopkins Berman Institute of Bioethics invites applications for a Postdoctoral Fellowship in the Ethics and Regulatory Aspects of Pragmatic Clinical Trials. This position includes pursuing independent research, working alongside faculty members involved with the ethics and regulatory aspects of large-scale pragmatic clinical trials and participating in the Hecht-Levi Postdoctoral Fellowship in Bioethics.

The postdoctoral fellow is expected to pursue one or more projects addressing the ethics and regulatory aspects of pragmatic clinical trials in collaboration with Berman Institute faculty members. The Fellow will actively engage with the Ethics and Regulatory Cores of the [NIH Pragmatic Trials Collaboratory] and the Pragmatic and Implementation Studies for the Management of Pain to Reduce Opioid Prescribing (PRISM) Resource Coordinating Center.

As a member of the Hecht-Levi cohort of Bioethics Postdoctoral Fellows at the Berman Institute, the Fellow will have access to Berman Institute faculty and resources, including weekly seminars, presentations, discussions with leading academics and policy makers, professional development training, outreach efforts, and teaching opportunities commensurate with experience and background.

Read the full information about the fellowship. Applications are due by December 16, 2022.

September 13, 2022: IMPACT Collaboratory Extends Deadline for NIH Collaboratory Trial Letters of Intent

Logo for the NIA IMPACT CollaboratoryThe deadline to submit letters of intent for the NIA IMPACT NIH Collaboratory Trials Program has been extended to September 30, 2022.

This summer, the IMPACT Collaboratory announced a request for applications for its NIH Collaboratory Trials Program.  This funding mechanism supports large-scale pragmatic clinical trials embedded in healthcare systems to test the effectiveness of nonpharmacological interventions for people living with Alzheimer disease and related dementias and their care partners. The interventions will typically encompass relatively simple system changes or direct patient outreach, or successfully piloted programs ready for testing at scale. Awards are for $500,000 in direct costs for 18 months.

Prospective applicants should email their 1-page letter of intent describing their proposed NIH Collaboratory Trial to IMPACTcollaboratory@hsl.harvard.edu. This information will help determine whether the proposed project aligns with the goals of the request for applications prior to a full application. The goal of these NIH Collaboratory Trials is to generate evidence on effective care delivery practices that can be expanded and/or implemented in other systems.

An informational webinar about the program is available.

More than 5 million Americans are living with Alzheimer disease and related dementias. They are particularly vulnerable to receiving uncoordinated and poor-quality care, which contributes to adverse health outcomes and misuse of resources. The mission of the IMPACT Collaboratory is to advance care for persons with dementia and their caregivers in real-world settings by building national capacity to conduct pragmatic clinical trials that test interventions embedded in healthcare systems.

The NIA IMPACT Collaboratory is supported by a grant from the National Institute on Aging.

August 18, 2022: Rural and Remote Populations Are Focus of Funding Opportunity From NIH HEAL Initiative

NIH Heal Initiative logoThe NIH HEAL Initiative℠, or Helping to End Addiction Long-Term Initiative℠, announced its intent to publish a new funding opportunity for cooperative research that will accelerate implementation of nonopioid interventions for chronic pain management in rural and remote populations. The initiative will support pragmatic, implementation, and hybrid effectiveness-implementation trials that study strategies for equitably and efficiently implementing effective interventions and evidence-based pain management guidelines in rural and remote communities.

The funding opportunity announcement is expected to be published in fall 2022, with an expected application due date in winter 2022. Funded projects will become part of the NIH HEAL Initiative’s PRISM (Pragmatic and Implementation Studies to Improve the Management of Pain and Reduce Opioid Prescribing) program.

The NIH Collaboratory Coordinating Center serves as the PRISM Resource Coordinating Center. Six PRISM NIH Collaboratory Trials within the NIH Collaboratory are studying the real-world effectiveness of nonpharmacologic interventions for pain and assessing the implementation of these interventions to improve pain management and reduce reliance on opioids.

Read the complete Notice of Intent to Publish a Funding Opportunity Announcement for HEAL Initiative: Prevention and Management of Chronic Pain in Rural Populations (UG3/UH3, Clinical Trials Required).

August 11, 2022: New Funding Opportunities From NIH HEAL Initiative Will Support Sickle Cell Disease Pain Management

NIH Heal Initiative logoThe Helping to End Addiction Long-Term Initiative℠, or NIH HEAL Initiative℠, recently published 2 funding opportunity announcements soliciting applications focused on sickle cell disease (SCD) pain management. The effort is co-led by the National Center for Complementary and Integrative Health and the National Heart, Lung, and Blood Institute, with support from other NIH Institutes, Centers, and Offices.

  • RFA-AT-23-001, “HEAL Initiative: Pragmatic and Implementation Studies for the Management of Sickle Cell Disease Pain” (UG3/UH3, Clinical Trials Optional) will support multisite embedded pragmatic or implementation trials to inform the uptake of pharmacologic, nonpharmacologic, and/or multicomponent approaches for acute and/or chronic SCD pain management in healthcare systems that serve the SCD population.
  • RFA-AT-23-002, “HEAL Initiative: Sickle Cell Disease Pain Management Trials Utilizing the Pain Management Effectiveness Research Network Cooperative Agreement” (UG3/UH3, Clinical Trial Required), will support multisite effectiveness clinical trials of pharmacologic, nonpharmacologic, and/or multicomponent approaches for acute and/or chronic SCD pain management, allowing continued opioid pain management as needed.

August 9, 2022: NIH HEAL Initiative Announces Funding Opportunity for Prevention Research in Community Health Centers

NIH Heal Initiative logoThe Helping to End Addiction Long-Term Initiative℠, or NIH HEAL Initiative℠, is seeking applications for opioid misuse prevention research in community health centers.

The funding opportunity announcement, RFA-DA-23-048: HEAL Initiative: Research Studies to Develop and Implement Interventions to Prevent Opioid Misuse in Community Health Centers, supports interdisciplinary teams to study the development, adaptation, and/or implementation of interventions to prevent misuse of opioids and other substances. Research will be supported through exploratory/developmental phase awards that may not exceed 5 years, allocating up to 2 years of funding for development of the project and up to 4 years for a full test of the research aims. Applications are due November 8, 2022.

The National Institute on Drug Abuse will hold a webinar on September 6 for potential applicants. Register for the webinar.  For more information, contact Sarah Steverman at sarah.steverman@nih.gov.