Analysis Plan
Section 1
Introduction
Pragmatic clinical trial designs, particularly those that use cluster randomization or other novel methods, pose challenges during the study design phase (Cook et al 2016). Here, we briefly examine current challenges in the design of pragmatic trials, as well as potential solutions and future directions for further exploration.
SECTIONS
CHAPTER SECTIONS
REFERENCES
Cook AJ, Delong E, Murray DM, Vollmer WM, Heagerty PJ. 2016. Statistical lessons learned for designing cluster randomized pragmatic clinical trials from the NIH Health Care Systems Collaboratory Biostatistics and Design Core. Clin Trials. 13:504-512. doi:10.1177/1740774516646578. PMID: 27179253.