The deadline to submit letters of intent for the NIA IMPACT NIH Collaboratory Trials Program has been extended to September 30, 2022.

This summer, the IMPACT Collaboratory announced a request for applications for its NIH Collaboratory Trials Program.  This funding mechanism supports large-scale pragmatic clinical trials embedded in healthcare systems to test the effectiveness of nonpharmacological interventions for people living with Alzheimer disease and related dementias and their care partners. The interventions will typically encompass relatively simple system changes or direct patient outreach, or successfully piloted programs ready for testing at scale. Awards are for $500,000 in direct costs for 18 months.

Prospective applicants should email their 1-page letter of intent describing their proposed NIH Collaboratory Trial to IMPACTcollaboratory@hsl.harvard.edu. This information will help determine whether the proposed project aligns with the goals of the request for applications prior to a full application. The goal of these NIH Collaboratory Trials is to generate evidence on effective care delivery practices that can be expanded and/or implemented in other systems.

An informational webinar about the program is available.

More than 5 million Americans are living with Alzheimer disease and related dementias. They are particularly vulnerable to receiving uncoordinated and poor-quality care, which contributes to adverse health outcomes and misuse of resources. The mission of the IMPACT Collaboratory is to advance care for persons with dementia and their caregivers in real-world settings by building national capacity to conduct pragmatic clinical trials that test interventions embedded in healthcare systems.

The NIA IMPACT Collaboratory is supported by a grant from the National Institute on Aging.