NIH Collaboratory Trials

NIH Collaboratory Trials

Our Reach

These large-scale pragmatic clinical trials are conducted in partnership with healthcare systems. They cover a range of clinical areas spanning 14 NIH Institutes and Centers. Together, the trials include >940,000 patient participants.

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PRISM Trials

AIM-CP

Adapting and Implementing a Nurse Care Management Model to Care for Rural Patients with Chronic Pain

Sebastian Tong, MD, MPH
Kushang Patel, PhD, MPH

University of Washington

ARBOR-Telehealth

Advancing Rural Back Pain Outcomes through Rehabilitation Telehealth

Richard L. Skolasky Jr., ScD, MA
Kevin McLaughlin, DPT

Johns Hopkins University

BackInAction

Pragmatic Trial of Acupuncture for Chronic Low Back Pain in Older Adults (BackInAction)

Lynn DeBar, Andrea J. Cook

Kaiser Foundation Research Institute

FM-TIPS

Fibromyalgia TENS in Physical Therapy Study (FM-TIPS)

Leslie Crofford, Kathleen Sluka

University of Iowa

GRACE

Hybrid Effectiveness-Implementation Trial of Guided Relaxation and Acupuncture for Chronic Sickle Cell Disease Pain (GRACE)

Ardith Doorenbos, Judith Schlaeger, Robert Molokie, Miriam Ezenwa, Nirmish Shah

University of Illinois at Chicago

RAMP

Reaching Rural Veterans: Applying Mind-Body Skills for Pain Using a Whole Health Telehealth Intervention

Diana Burgess, PhD
Roni L. Evans, DC, MS, PhD
Katherine E. Hadlandsmyth, PhD

Center for Veterans Research and Education

Other Active Trials

BEST-ICU

Behavioral Economic and Staffing Strategies to Increase Adoption of the ABCDEF Bundle in the ICU

Michele Balas, Eduard Vasilevskis

University of Nebraska Medical Center

ICD-Pieces

Improving Chronic Disease Management with Pieces (ICD-Pieces)

Miguel Vazquez

UT Southwestern Medical Center

IMPACt-LBP

Implementation of the American College of Physicians Guideline for Low Back Pain (IMPACt-LBP)

Christine Goertz, Adam Goode, Jon Lurie, Hrishikesh Chakraborty

Duke University

INSPIRE

INtelligent Stewardship Prompts to Improve Real-time Empiric Antibiotic Selection for Patients

Susan S. Huang, Rich Platt, Shruti Gohil

Harvard Pilgrim Health Care

PRIM-ER

Primary Palliative Care for Emergency Medicine (PRIM-ER)

Corita Grudzen, Keith Goldfeld

New York University School of Medicine

TAICHIKNEE

Remote Tai Chi for Knee Osteoarthritis: an Embedded Pragmatic Trial

Chenchen Wang, Helen Lavretsky, Eric Roseen, Robert Saper

Tufts Medicine Tufts Medical Center

Completed Trials

PROVEN

Pragmatic Trial of Video Education in Nursing Homes (PROVEN)

Vincent Mor, Angelo Volandes, Susan Mitchell

Brown University School of Medicine

SPOT

Suicide Prevention Outreach Trial (SPOT)

Gregory Simon

Kaiser Permanente Washington Health Research Institute

Inactive