Funding

August 2, 2022: IMPACT Collaboratory Announces New Funding Opportunities

Posted on by Damon Seils

Logo for the NIA IMPACT CollaboratoryThe NIA IMPACT Collaboratory announced requests for applications for 2 new funding opportunities: the Pilot Grant Program and the NIH Collaboratory Trials Program.  These programs support research and training to increase the nation’s capacity to conduct pragmatic clinical trials of nonpharmacological interventions within healthcare systems to improve care for people living with Alzheimer disease related dementias and their care partners.

The 1-year pilot grant awards will be eligible for funding of up to $175,000. The awards will support pilot projects that aim to generate preliminary data for the design and conduct of full-scale embedded pragmatic clinical trials of nonpharmacologic interventions in healthcare systems for persons living with Alzheimer disease and related dementias and their care partners.

The 2-year NIH Collaboratory Trial awards will be eligible for up to $500,000 for full-scale, Stage IV effectiveness ePCTs (based on the NIH Stage Model) that test, measure, and evaluate the effect of a care delivery intervention program in healthcare systems for people living with Alzheimer disease and related dementias and their care partners.

More than 5 million Americans are living with Alzheimer disease and related dementias. They are particularly vulnerable to receiving uncoordinated and poor-quality care, which contributes to adverse health outcomes and misuse of resources. The mission of the IMPACT Collaboratory is to advance care for persons with dementia and their caregivers in real-world settings by building national capacity to conduct pragmatic clinical trials that test interventions embedded in healthcare systems.

The NIA IMPACT Collaboratory is supported by a grant from the National Institute on Aging.

July 12, 2022: IMPACT Collaboratory to Publish Funding Opportunities for Pilot and NIH Collaboratory Trial Programs

Posted on by Damon Seils

NIA IMPACT Collaboratory logoThe NIA IMPACT Collaboratory will publish new funding opportunities on August 15 for a pilot grants program and a NIH Collaboratory Trials program.

The 1-year pilot grant awards will be eligible for funding of up to $175,000. The awards will support pilot projects that aim to generate preliminary data for the design and conduct of full-scale embedded pragmatic clinical trials of nonpharmacologic interventions in healthcare systems for persons living with Alzheimer disease and related dementias and their care partners.

The 2-year NIH Collaboratory Trial awards will be eligible for up to $500,000 for full-scale, Stage IV effectiveness ePCTs (based on the NIH Stage Model) that test, measure, and evaluate the effect of a care delivery intervention program in healthcare systems for people living with Alzheimer disease and related dementias and their care partners.

More than 5 million Americans are living with Alzheimer disease and related dementias. They are particularly vulnerable to receiving uncoordinated and poor-quality care, which contributes to adverse health outcomes and misuse of resources. The mission of the IMPACT Collaboratory is to advance care for persons with dementia and their caregivers in real-world settings by building national capacity to conduct pragmatic clinical trials that test interventions embedded in healthcare systems.

The NIA IMPACT Collaboratory is supported by a grant from the National Institute on Aging.

June 15, 2022: IMPACT Collaboratory Announces Funding for Career Development Awards

Posted on by Damon Seils

Logo for the NIA IMPACT CollaboratoryThe National Institute on Aging (NIA) Imbedded Pragmatic Alzheimer’s Disease (AD) and AD-Related Dementias (AD/ADRD) Clinical Trials (IMPACT) Collaboratory is now accepting applications for its Career Development Award (CDA) program. These CDAs support the development of MD, PhD, or equivalent researchers who seek careers conducting embedded pragmatic clinical trials (ePCTs) for people living with AD/ADRD and their care partners.

The program will fund 2-year CDAs and will prioritize applications that address dementia care for people of all backgrounds and promote health equity. Each award will provide up to $220,000 in direct costs over 2 years with an indirect cost rate capped at 8%. Awardees are required to devote a minimum of 75% effort toward the goals of the award.

Eligible applicants include MD, PhD, or equivalent researchers who seek careers conducting ePCTs for people living with AD/ADRD and their care partners. Applicants are typically within 7 years of their postdoctoral training program at the time of application. Exceptions will be made in this round of funding for investigators with more than 7 years who can demonstrate evidence of changing their career path to pursue research on ePCTs among people living with dementia. Such applicants must request prior approval.

Applications are due Thursday, September 15, 2022. An informational webinar will be hosted on Wednesday, June 29, at 2:00 PM eastern to provide investigators with an overview of application details. Investigators will have the opportunity to ask questions. Use this link for required preregistration.

Learn more by reading answers to frequently asked questions regarding this award.

March 17, 2022: NIH Will Fund New NIH Collaboratory Trials That Address Health Disparities

Posted on by Damon Seils

Promotional banner for funding opportunity announcementThe NIH released a request for applications (RFA) for new NIH Pragmatic Trials Collaboratory Trial grants that address health disparities. NIH program and review staff will discuss the funding opportunity in an upcoming webinar. Registration for the webinar is required.

The RFA for this funding opportunity encourages applications that focus on improving health outcomes in populations that experience health disparities, such as higher rates of disease or mortality compared with the general population. Applications are due June 17, 2022. Letters of intent are due 30 days prior (May 17, 2022).

For the purposes of this funding opportunity, the NIH-designated U.S. health disparity populations definition includes: Blacks/African Americans, Hispanics/ Latinos, American Indians/Alaska Natives, Asian Americans, Native Hawaiians and other Pacific Islanders, socioeconomically disadvantaged populations, underserved rural populations, and sexual and gender minorities. 

Similar to the NIH Pragmatic Trials Collaboratory’s other NIH Collaboratory Trials, the new projects will have a planning and implementation phase and will be large-scale pragmatic or implementation trials that are embedded in healthcare delivery systems. The overarching goal of the projects is to improve care delivery and health outcomes across the lifespan.

Read our Living Textbook chapter about how to develop a compelling grant application for a pragmatic clinical trial.

February 3, 2022: IMPACT Collaboratory Seeks Letters of Intent for Pilot Grants Program

Posted on by Damon Seils

NIA IMPACT Collaboratory logoThe NIA IMPACT Collaboratory is seeking letters of intent from interested applicants for Cycle 4A of its Pilot Grants Program.

The 1-year pilot grant awards will fund up to $175,000 in direct costs for pilot studies that aim to generate preliminary data for full-scale embedded pragmatic clinical trials of nonpharmacologic interventions in healthcare systems for persons living with Alzheimer disease and related dementias and/or their care partners. In this grant cycle, the program will give priority to applications aim that improve care through behavioral economics “nudge” interventions; reduce inequities in healthcare; reduce potentially inappropriate medication use through de-prescribing; or improve care in emergency departments.

The required letters of intent are due by March 4. An optional informational webinar on February 14 will provide an overview of application details and an opportunity to ask questions. More information is available on the IMPACT Collaboratory website.

More than 5 million Americans are living with Alzheimer disease and related dementias. They are particularly vulnerable to receiving uncoordinated and poor-quality care, which contributes to adverse health outcomes and misuse of resources. The mission of the IMPACT Collaboratory is to advance care for persons with dementia and their caregivers in real-world settings by building national capacity to conduct pragmatic clinical trials that test interventions embedded in healthcare systems.

The NIA IMPACT Collaboratory is supported by a grant from the National Institute on Aging.

January 11, 2022: New Funding Opportunities Support Investigators at All Levels in Pragmatic Clinical Research

Posted on by Damon Seils

Logo for the NIA IMPACT CollaboratoryThe NIA IMPACT Collaboratory announced 2 new funding opportunities for researchers at all levels who are interested in pragmatic clinical trials embedded in healthcare systems (ePCTs). They include career development awards for early-stage researchers and a scholars program for midlevel and senior researchers.

  • Career Development Award: The IMPACT Collaboratory will fund 2-year career development awards to support the development of early-stage researchers who are seeking careers conducting ePCTs for people living with Alzheimer disease or related dementias and their care partners. Applications are due March 18. An optional informational webinar will be held on February 1.
  • Health Care System Scholars Program – The IMPACT Collaboratory’s Health Care System Scholars Program offers midlevel and senior investigators an opportunity to develop ePCTs with healthcare systems interested in improving the care provided to people living with Alzheimer disease or related dementias and their care partners. Letters of intent are due February 8. An optional informational webinar will be held on January 20.

The NIA IMPACT Collaboratory is supported by a grant from the National Institute on Aging. Its mission is to advance care for persons with dementia and their caregivers in real-world settings by building national capacity to conduct pragmatic clinical trials that test interventions embedded in healthcare systems.

December 20, 2021: NIH Supplemental Funding Available for Bioethics Capacity Building

Posted on by Damon Seils

NIH logoThe NIH announced the availability of an administrative supplement to fund research on ethical considerations related to biomedical research and projects that support capacity building in bioethics.

Over the past 3 years, the NIH Office of the Director has partnered with NIH Institutes and Centers to support projects spanning the wide range of intersections between bioethics and biomedical research. The new funding opportunity applies to both basic and clinical research and supports a variety of research projects, from ethical considerations in emerging technologies to developing capacity to further engage research participants as partners in research. Applications will be accepted until March 17, 2022.

View the official notice.

October 25, 2021: NIH HEAL Initiative Issues RFA for Projects that Advance Health Equity in Pain Management

Posted on by terren.green@duke.edu

The Helping to End Addiction Long-termSM Initiative, or NIH HEAL InitiativeSM recently announced a funding opportunity for new studies that aim to develop, test, and implement interventions that mitigate bias, discrimination, socioeconomic, or environmental barriers to quality pain assessment, treatment, and management for populations that experience health disparities (HDPs) in the United States.

For the purposes of this funding opportunity, the NIH-designated U.S. health disparity populations definition includes: Blacks/African Americans, Hispanics/ Latinos, American Indians/Alaska Natives, Asian Americans, Native Hawaiians and other Pacific Islanders, socioeconomically disadvantaged populations, underserved rural populations, and sexual and gender minorities.

The NIH HEAL Initiative supports research to improve treatment for opioid misuse and addiction and enhance pain management. This RFA calls for applications that “demonstrate an existing health disparity or health disparities in acute and/or chronic pain in the population of interest and outline a detailed plan for an evidence-based intervention to mitigate or eliminate the disparity(disparities) to improve pain and pain-related outcomes.”

Applications are due by 5pm on December 9, 2021.  Letters of intent are due 30 days prior (November 9, 2021).

This award will support a 1 to 2-year, milestone-driven planning phase (R61) with the possibility of an additional 4-year implementation phase (R33).

Read the full request for applications.

The Helping to End Addiction Long-termSM Initiative, or NIH HEAL InitiativeSM, is an aggressive, trans-NIH effort to speed scientific solutions to stem the national opioid public health crisis. Launched in April 2018, the initiative is focused on improving prevention and treatment strategies for opioid misuse and addiction, and enhancing pain management. For more information, visit: https://heal.nih.gov.

October 19, 2021: NIH Issues RFA for New NIH Collaboratory Trials That Address Health Disparities

Posted on by Karen Staman

NIH logoThe NIH recently released a request for applications (RFA) for new NIH Collaboratory Trial grants. The RFA encourages applications that focus on improving health outcomes in populations that experience health disparities, such as higher rates of disease or mortality compared with the general population. These populations may be defined by race, ethnicity, geography, or socioeconomic status.

Applications are due December 15, 2021. Letters of intent are due 30 days prior (November 15, 2021).

For the purposes of this funding opportunity, the NIH-designated U.S. health disparity populations definition includes: Blacks/African Americans, Hispanics/ Latinos, American Indians/Alaska Natives, Asian Americans, Native Hawaiians and other Pacific Islanders, socioeconomically disadvantaged populations, underserved rural populations, and sexual and gender minorities. 

Similar to the NIH Collaboratory’s other NIH Collaboratory Trials, the new projects will have a planning and implementation phase and will be large-scale pragmatic or implementation trials that are embedded in healthcare delivery systems. The overarching goal of the projects is to improve care delivery and health outcomes in Americans across the lifespan.

Read the full request for applications.

Read our Living Textbook chapter about how to develop a compelling grant application for a pragmatic clinical trial.

October 18, 2021: Application Period Opens for Postdoctoral Fellowship in Ethics and Regulatory Aspects of PCTs

Posted on by Damon Seils

Johns Hopkins Berman Institute of Bioethics logoThe Johns Hopkins Berman Institute of Bioethics this week opened the application period for its 2022-2023 postdoctoral fellowships, including a Postdoctoral Fellowship in the Ethics and Regulatory Aspects of Pragmatic Clinical Trials.

From the announcement:

The Johns Hopkins Berman Institute of Bioethics invites applications for a Postdoctoral Fellowship in the Ethics and Regulatory Aspects of Pragmatic Clinical Trials. This position includes pursuing independent research, working alongside faculty members involved with the ethics and regulatory aspects of large-scale pragmatic clinical trials and participating in the Hecht-Levi Postdoctoral Fellowship in Bioethics.

The postdoctoral fellow is expected to pursue one or more projects addressing the ethics and regulatory aspects of pragmatic clinical trials in collaboration with Berman Institute faculty members. The Fellow will actively engage with the Ethics and Regulatory Cores of the NIH Health Care Systems Research Collaboratory and the Pragmatic and Implementation Studies for the Management of Pain to Reduce Opioid Prescribing (PRISM) Resource Coordinating Center.

As a member of the Hecht-Levi cohort of Bioethics Postdoctoral Fellows at the Berman Institute, the Fellow will have access to Berman Institute faculty and resources, including weekly seminars, presentations, discussions with leading academics and policy makers, professional development training, outreach efforts, and teaching opportunities commensurate with experience and background.

Read the full information about the fellowship. Applications are due by Friday, December 19, 2021.