September 8, 2026: NIH Collaboratory Training Resources Offer Practical Guidance for All Engaged in Pragmatic Clinical Trial Research

The NIH Collaboratory Living Textbook offers a variety of training resources intended for researchers, research team members, clinicians, healthcare system leaders and staff, and others involved in pragmatic clinical trial (PCT) research. These resources cover foundational information preparing learners to engage meaningfully with PCT research.

A Learning Modules section provides a series of self-paced videos featuring NIH Collaboratory experts covering PCT study funding, design, endpoint selection, and randomization strategies. Pathways to Learning provides comprehensive information on PCT study design while offering Continuing Education Units through the Duke University Health System’s Department of Clinical Education and Professional Development.

A wide range of videos, resources, and workshops provide learners with information, downloadable tools, guidance documents, templates, and relevant example materials from NIH Collaboratory Trials. Training resources are categorized by topic allowing research teams to easily find materials relevant to their interests.

All training resources can be accessed through the Living Textbook’s Training Resources page. New topics and materials are added frequently.

January 22, 2019: New Self-Paced ePCT Training Course Available

The NIH Collaboratory is pleased to announce the availability of a new self-paced, 10-module introductory course on how to design, conduct, and disseminate embedded PCTs (ePCTs). This course presents condensed material from the inaugural ePCT Training Workshop held in 2018 and provides users with important things to know and do when designing an ePCT, along with helpful links to additional learning resources within the Living Textbook.

Also available in the Living Textbook are links to videocast workshops hosted by the NIH on a range of ePCT topics including:

  • Embedded PCTs of therapeutic A versus B interventions
  • Unique opportunities for disseminating, implementing, and sustaining evidence-based practices into clinical care
  • Ethical and regulatory issues of PCTs

For these and other ePCT resources, visit the Training Resources webpage.