Welcome to your source for training materials on how to design, conduct, and disseminate embedded pragmatic clinical trials (ePCTs). These materials reflect the knowledge, insight, and best practices acquired by the NIH Collaboratory program and its ePCT Demonstration Projects. The resources are being shared with the research community to provide guidance about building partnerships with health systems and overcoming the challenges of conducting pragmatic research. We hope you find this information useful in implementing ePCTs.
We encourage use of these training materials and ask that credit be given to the NIH Health Care Systems Research Collaboratory. For more information, visit the section on How to Cite the Living Textbook.
Drs. Lesley Curtis and Wendy Weber of the NIH Collaboratory discuss highlights from the inaugural ePCT Training Workshop and plans for making more training resources available in the future.
- Introduction to ePCTs: Self-Paced Study January 17, 2019
Ten self-paced learning modules on how to design, conduct, and disseminate ePCTs
- NIH-Hosted ePCT Workshops January 17, 2019
Recordings and materials from NIH-hosted workshops with ePCT thought leaders and stakeholders
Upcoming Learning Opportunities
- March 29 @ 1:00 pm - 2:00 pm
- April 5 @ 1:00 pm - 2:00 pm
Grand Rounds April 12: Development of Harmonized Outcome Measures for Use in Research and Clinical PracticeApril 12 @ 1:00 pm - 2:00 pm
Grand Rounds April 19: The Trauma Survivors Outcomes & Support (TSOS) Pragmatic Trial : Revisiting Effectiveness & Implementation AimsApril 19 @ 1:00 pm - 2:00 pm
- March 13, 2019: PROVEN Publishes Study of Nursing Home Characteristics Associated With Implementation of an Advance Care Planning Video Intervention The Collaboratory Demonstration Project Pragmatic Trial of Video Education in Nursing Homes (PROVEN) is testing the effectiveness of a novel advance care planning (ACP) video education program in 360 nursing ...
- March 6, 2018: Results of the Active Bathing to Eliminate (ABATE) Infection Trial Published in The Lancet The Active Bathing to Eliminate (ABATE) Infection trial compared routine bathing to decolonization with universal chlorhexidine and targeted nasal mupirocin in non-critical-care units. Similar interventions have been found to reduce ...
- March 5, 2019: New Living Textbook Section on Using Death as an Endpoint Using death as an endpoint in pragmatic clinical trials is challenging because there are no standardized processes for ascertaining patient deaths in the United States. If a patient dies outside ...