Learning Modules
Listen to our experts answer key questions about pragmatic clinical trials. You can select a question and view a series of related learning topics or work through each group of videos sequentially.
These videos are intended for researchers, research team members, clinicians, healthcare system leaders and staff, and others involved with PCTs. They offer foundational information so learners will be prepared to engage meaningfully with a PCT.
For learners preparing to lead a PCT, we recommend undertaking additional education, such as workshops and hands-on learning.
What Is A Pragmatic Clinical Trial?
This collection of videos describes characteristics of pragmatic clinical trials and when a pragmatic clinical trial is a good fit.
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What Are Endpoints and Outcomes?
This collection of videos describes endpoints and outcomes in pragmatic clinical trials and how data sources inform the choice of endpoints and outcomes in pragmatic trials.
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Understanding Cluster Randomization
This collection of videos answers questions about cluster randomization, the intraclass correlation coefficient, power and detectable difference, and outcomes.
Learning topics
- What are the Reasons to Randomize Clusters Instead of Individuals?
Transcript - What Is Outcome Clustering, and How Can It Affect a Trial?
Transcript - What Is the Intraclass Correlation Coefficient?
Transcript - How Does Clustering Affect Power and Detectable Difference?
Transcript - How Do You Estimate the Degree of Clustering for Outcomes?
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Is a PCT Right for Your Research Question?
This video describes questions to ask to determine if a pragmatic clinical trial is a good fit for your research question.
Learning topic
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How Do I Choose the Right Study Design?
This collection of videos describes reasons to randomize clusters, types of CRT designs, reasons for using the stepped-wedge design, and how to choose a study design.
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How Do I Define Outcomes With Electronic Health Record Data?
This collection of videos describes challenges of using EHR data, key factors in using EHR data for endpoints and outcomes, computable phenotypes, and benefits of standardizing phenotype definitions.
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Using Electronic Health Record Data in Pragmatic Clinical Trials
Writing a Successful Grant Application
This collection of videos describes several topics related to writing a successful grant application including common pitfalls, "must dos," what to avoid, and success strategies.
Learning topics
- What Are Common Pitfalls in Writing PCT Grant Applications?
Transcript - Is it Important to Explain the Definition of Pragmatic to Grant Reviewers?
Transcript - What Are the “Must Dos” of Writing PCT Grant Applications?
Transcript - What Should I Avoid When Writing PCT Grant Applications?
Transcript - What Are Some Success Strategies When Writing PCT Grant Applications?
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Designing Pragmatic Trials That Are Fit For Purpose
This video describes how to design trials that are fit for purpose.