January 24, 2024: In This Friday’s PCT Grand Rounds, Healthcare AI That’s Safe, Effective, and Equitable

Suresh Balu and Mark Sendak

In this Friday's PCT Grand Rounds, Suresh Balu and Mark Sendak of Duke University will present "Advancing the Safe, Effective, and Equitable Use of AI in Healthcare."

The Grand Rounds session will be held on Friday, January 26, 2024, at 1:00 pm eastern.

Balu is the director of the Duke Institute for Health Innovation (DIHI) and the associate dean for innovation and partnership in the Duke University School of Medicine. Sendak is the population health and data science lead at DIHI.

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January 17, 2024: In This Friday’s PCT Grand Rounds, Why Are Imaging Trials Different?

Dr. Pamela Douglas (Photo: Erin Roth, Duke Health)

In this Friday's PCT Grand Rounds, Pamela Douglas of Duke University will present "Why Are Imaging RCTs Different? Lessons From Chest Pain Evaluation Trials."

The Grand Rounds session will be held on Friday, January 19, 2024, at 1:00 pm eastern.

Douglas is the Ursula Geller Professor of Research in Cardiovascular Diseases at Duke University and a past president of both the American College of Cardiology and the American Society of Echocardiography.

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January 10, 2024: In This Friday’s PCT Grand Rounds, a Lottery for Allocating Scarce COVID-19 Resources

In this Friday's PCT Grand Rounds, Erin McCreary of the University of Pittsburgh will present "Design and Implementation of a Weighted Lottery to Equitably Allocate Scarce COVID-19 Resources."

The Grand Rounds session will be held on Friday, January 12, 2024, at 1:00 pm eastern.

McCreary is a clinical assistant professor of medicine at the University of Pittsburgh and the director of infectious diseases improvement and clinical research innovation at UPMC. She is also the president-elect of the Society of Infectious Diseases Pharmacists.

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January 3, 2024: Special Biostatistics Series Concludes With Missing Data in Cluster Randomized Trials

In this Friday's PCT Grand Rounds, Rui Wang of Harvard Medical School will offer the final session in our special series, Advances in the Design and Analysis of Pragmatic Clinical Trials, with "Methods for Handling Missing Data in Cluster Randomized Trials." The session will be held on Friday, January 5, at 1:00 pm eastern.

Wang is an associate professor of population medicine and the director of the Division of Biostatistics in the Department of Population Medicine at Harvard Medical School and the Harvard Pilgrim Health Care Institute. She is also an associate professor in the Department of Biostatistics at the Harvard T.H. Chan School of Public Health. She is a longtime member of the NIH Pragmatic Trials Collaboratory's Biostatistics and Study Design Core Working Group.

This session's moderator, Fan Li, is an assistant professor of biostatistics at the Yale School of Public Health.

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This special Grand Rounds series includes moderated webinar discussions that bring together biostatisticians, clinical trials methodologists, and investigators to discuss challenges and share lessons learned in the design, implementation, and analysis of pragmatic trials. Download the series flyer and see the full schedule below, including archived webinar recordings and slides from previous sessions.

All sessions are free and open to the public. No registration is required.

December 13, 2023: In This Week’s PCT Grand Rounds, a Path Forward for Diversifying Clinical Trials

In this Friday's PCT Grand Rounds, Roxana Mehran of the Icahn School of Medicine at Mount Sinai will present "Diversifying Clinical Trials: A Path Forward."

The Grand Rounds session will be held on Friday, December 15, 2023, at 1:00 pm eastern.

Mehran is a professor of medicine and the director of interventional cardiovascular research and clinical trials at the Zena and Michael A. Wiener Cardiovascular Institute at the Mount Sinai School of Medicine.

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December 6, 2023: Jumpstarting Communication About Goals of Care, in This Week’s PCT Grand Rounds

Headshots of Drs. Ruth Engelberg, Erin Kross, and Robert LeeIn this Friday's PCT Grand Rounds, Ruth Engelberg, Erin Kross, and Robert Lee of the University of Washington will present "A Pragmatic Randomized Trial of the Jumpstart Intervention to Promote Communication About Goals of Care for Hospitalized Patients With Serious Illness."

The Grand Rounds session will be held on Friday, December 8, 2023, at 1:00 pm eastern.

Engelberg is a research professor of medicine, Kross is an associate professor of medicine, and Lee is an assistant professor of medicine in pulmonary, critical care, and sleep medicine at the University of Washington.

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November 29, 2023: Special Biostatistics Series Continues With Guidelines for Stepped-Wedge Trials

In this Friday’s PCT Grand Rounds, Jim Hughes of the University of Washington will continue our special series, Advances in the Design and Analysis of Pragmatic Clinical Trials, with his presentation, “Guidelines for Design and Analysis of Stepped-Wedge Trials.” The session will be held on Friday, December 1, at 1:00 pm eastern.

Hughes is a professor emeritus of biostatistics at the University of Washington. This session’s moderator, Patrick Heagerty, is a professor of biostatistics at the University of Washington and a cochair of the NIH Pragmatic Trials Collaboratory’s Biostatistics and Study Design Core.

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This special Grand Rounds series will include additional moderated webinar discussions that bring together biostatisticians, clinical trials methodologists, and investigators to discuss challenges and share lessons learned in the design, implementation, and analysis of pragmatic trials. Download the series flyer and see the full schedule below.

All sessions are free and open to the public; no registration is required.

November 15, 2023: In This Friday’s PCT Grand Rounds, Results From the Nudge NIH Collaboratory Trial

In this Friday's PCT Grand Rounds, Michael Ho and Sheana Bull of the University of Colorado will present "Personalized Patient Data and Behavioral Nudges to Improve Adherence to Chronic Cardiovascular Medications: Results From the Nudge Study."

The Grand Rounds session will be held on Friday, November 17, 2023, at 1:00 pm eastern.

Nudge is an NIH Collaboratory Trial. Ho is a professor of medicine and Bull is a professor of community and behavioral health at the University of Colorado. They are the co–principal investigators of Nudge.

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November 1, 2023: Special Biostatistics Series Continues With Complex Clustering in Pragmatic Trials

In this Friday’s PCT Grand Rounds, Jonathan Moyer of the NIH Office of Disease Prevention will continue our special series, Advances in the Design and Analysis of Pragmatic Clinical Trials, with his presentation, “The Perils and Pitfalls of Complex Clustering in Pragmatic Trials.” The session will be held on Friday, November 3, at 1:00 pm eastern and will be moderated by Andrea Cook.

Moyer is a statistician in the NIH Office of Disease Prevention. He is a longtime member of the NIH Pragmatic Trials Collaboratory’s Biostatistics and Study Design Core. This session’s moderator, Andrea Cook, is a senior biostatistics investigator in the Kaiser Permanente Washington Health Research Institute.

Join the online meeting.

This special Grand Rounds series will include additional moderated webinar discussions that bring together biostatisticians, clinical trials methodologists, and investigators to discuss challenges and share lessons learned in the design, implementation, and analysis of pragmatic trials. Download the series flyer and see the full schedule below.

All sessions are free and open to the public; no registration is required.

October 25, 2023: In This Friday’s PCT Grand Rounds, Krumholz Presents PaxLC Trial of Paxlovid for Long COVID

Banner showing a headshot of Dr. Harlan Krumholz and the title of his upcoming PCT Grand Rounds Session, "Digital, Decentralized and Democratized: Lessons From The Yale PaxLC Trial."In this Friday’s PCT Grand Rounds, Harlan Krumholz of Yale University will present “Digital, Decentralized and Democratized: Lessons From the Yale PaxLC Trial.”

The Grand Rounds session will be held on Friday, October 27, 2023, at 1:00 pm eastern.

The PaxLC Trial is a decentralized study of Paxlovid in adult participants with long COVID. Krumholz, the principal investigator for the trial, is the Harold H. Hines, Jr Professor of Medicine at Yale University and the director of the Yale-New Haven Hospital Center for Outcomes Research and Evaluation.

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