The IMPACT Collaboratory last week published a request for applications for the second cycle of its NIH Collaboratory Trials Program.
IMPACT will fund up to 2 full-scale embedded pragmatic clinical trials that test, measure, and evaluate the effects of a nonpharmacological care delivery intervention program in a healthcare system for people living with Alzheimer disease and related dementias and their care partners. The goal of the NIH Collaboratory Trials Program is to generate evidence on effective care delivery practices that can be expanded and/or implemented in other systems.
The 1-year pilot grant awards will likely be eligible for funding of up to $175,000 in direct costs. The awards will support pilot projects that aim to generate preliminary data for the design and conduct of full-scale embedded pragmatic clinical trials of nonpharmacologic interventions in healthcare systems for persons living with Alzheimer disease and related dementias and/or their care partners. The IMPACT Collaboratory will give preference to applications that address care for traditionally marginalized or underrepresented populations in clinical research and those that promote health equity.
More than 5 million Americans are living with Alzheimer disease and related dementias. They are particularly vulnerable to receiving uncoordinated and poor-quality care, which contributes to adverse health outcomes and misuse of resources. The mission of the IMPACT Collaboratory is to advance care for persons with dementia and their caregivers in real-world settings by building national capacity to conduct pragmatic clinical trials that test interventions embedded in healthcare systems.
The NIA IMPACT Collaboratory is supported by a grant from the National Institute on Aging.
The NIA IMPACT Collaboratory will publish a request for applications for pilot grants on August 16, 2021, with letters of intent due September 17, 2021.
The 1-year pilot grant awards will likely be eligible for funding of up to $175,000 in direct costs. The awards will support pilot projects that aim to generate preliminary data for the design and conduct of full-scale embedded pragmatic clinical trials of nonpharmacologic interventions in healthcare systems for persons living with Alzheimer disease and related dementias and/or their care partners. The IMPACT Collaboratory will give preference to applications that address care for traditionally marginalized or underrepresented populations in clinical research and those that promote health equity.
More than 5 million Americans are living with Alzheimer disease and related dementias. They are particularly vulnerable to receiving uncoordinated and poor-quality care, which contributes to adverse health outcomes and misuse of resources. The mission of the IMPACT Collaboratory is to advance care for persons with dementia and their caregivers in real-world settings by building national capacity to conduct pragmatic clinical trials that test interventions embedded in healthcare systems.
The NIA IMPACT Collaboratory is supported by a grant from the National Institute on Aging.
The NIA IMPACT Collaboratory will publish a request for applications for pilot grants on August 16, 2021, with letters of intent due September 17, 2021.
The 1-year pilot grant awards will likely be eligible for funding of up to $175,000. The awards will support pilot projects that aim to generate preliminary data for the design and conduct of full-scale embedded pragmatic clinical trials of nonpharmacologic interventions in healthcare systems for persons living with Alzheimer disease and related dementias and/or their care partners. The IMPACT Collaboratory will give preference to applications that address care for traditionally marginalized or underrepresented populations in clinical research and those that promote health equity.
More than 5 million Americans are living with Alzheimer disease and related dementias. They are particularly vulnerable to receiving uncoordinated and poor-quality care, which contributes to adverse health outcomes and misuse of resources. The mission of the IMPACT Collaboratory is to advance care for persons with dementia and their caregivers in real-world settings by building national capacity to conduct pragmatic clinical trials that test interventions embedded in healthcare systems.
The NIA IMPACT Collaboratory is supported by a grant from the National Institute on Aging.
The NIA IMPACT Collaboratory has announced 3 new funding opportunities for researchers at all levels who are interested in pragmatic clinical trials embedded in healthcare systems (ePCTs). They include funding for NIH Collaboratory Trials, a new scholars program for junior and senior investigators, and a new cycle of funding for 1-year pilot studies.
NIH Collaboratory Trials Program: The IMPACT Collaboratory will fund up to 2 NIH Collaboratory Trials designed as full-scale ePCTs that test nonpharmacological interventions for people living with Alzheimer disease and related dementias (ADRD) and their care partners. The projects should generate evidence on effective care delivery practices that can be expanded or implemented in other healthcare systems. An informational webinar will be held on Thursday, February 11, at 2:00 pm ET.
Health Care System Scholars Program – A new Health Care Systems Embedded Research Scholars Program offers junior and senior investigators an opportunity to work directly with healthcare systems interested in improving the care provided to people living with dementia and their care partners. A informational webinar will be held on Thursday, February 11, at 1:00 pm ET.
Pilot Grants Program: One-year pilot studies are meant to generate preliminary data necessary to design and conduct future full-scale ePCTs. The IMPACT Collaboratory will consider applications for pilot studies that test nonpharmacological interventions embedded in healthcare system for people living with ADRD and their care partners. An informational webinar will be held on Monday, February 22, at 4:00 pm ET.
The NIA IMPACT Collaboratory is supported by a grant from the National Institute on Aging. Its mission is to advance care for persons with dementia and their caregivers in real-world settings by building national capacity to conduct pragmatic clinical trials that test interventions embedded in healthcare systems.
Nakela L. Cook, MD, MPH
Executive Director
Patient-Centered Outcomes Research Institute (PCORI)
Topic
Driving Toward Health Impact: Our Journey and Path Forward
Keywords
PCORI; Health outcomes; Health disparities; Patient-centered research; Comparative clinical effectiveness; COVID-19; Maternal health
Key Points
Despite improvements in health, disparities and variation in care remain—especially underscored by the unprecedented COVID-19 pandemic.
PCORI funds studies that can help patients and those who care for them make better informed healthcare choices.
PCORI has funded the HERO Registry to assess COVID-19 exposure responses and outcomes within the community of healthcare workers. Other research support is targeted toward vulnerable populations, healthcare delivery, and emerging health trends.
With PCORI 2.0, new funding will be available for large-scale, high-impact comparative effectiveness trials. Each study will include an initial phase to determine the feasibility and viability of the study and maximize the likelihood of success during the full-scale phase.
Discussion Themes
What are your observations regarding COVID-19’s impact on health, healthcare, and research that you think will be critical for PCORI's strategy? What will bring about the necessary innovations to the system?
Addressing maternal health disparities is a high priority in PCORI 2.0. The next phase will also expand PCORI’s role in collecting and generating relevant evidence and focusing on a deliberate and transparent process for implementation.
How will PCORI broaden its reach to reduce outcome disparities among people with disabilities?
The IMPACT Collaboratory last week published a request for applications for the second cycle of its NIH Collaboratory Trials Program.