2024

Dissemination and Implementation in Embedded Pragmatic Trials: Getting the Timing Right in Real-World Research: AcademyHealth (December 2024)

Posted on by Damon Seils

A photo from the 2024 AcademyHealth D&I Workshop showing panelists at a dais answering questions from workshop participants.December 8, 2024: The NIH Pragmatic Trials Collaboratory hosted a workshop at AcademyHealth's 17th Annual Conference on the Science of Dissemination and Implementation in Health. The workshop introduced concepts in the design, conduct, and implementation of pragmatic clinical trials embedded in healthcare systems, with a focus on methods relevant to health services researchers.

Agenda

Speaker Biographies

Program Overview

Participant Guide

Agenda and Slides

Morning Sessions

Welcome and Introduction
Emily O'Brien, PhD

Session 1: What Are Embedded Pragmatic Clinical Trials?
Beda Jean-Francois, PhD

Session 2: Trial Objectives and Design: An Overview of Hybrid Designs
Devon Check, PhD

Session 3: Engaging With Health System and Community Partners
Hayden Bosworth, PhD

Session 4: ePCTs in Context: Small Group Work and Panel Discussion With NIH Collaboratory Trial Investigators
Moderator: Angelo Volandes, MD, MPH
*This session includes case study presentations.

Afternoon Sessions

Session 5: Measuring Outcomes
Angelo Volandes, MD, MPH

Session 6: ePCT Design
Jonathan Moyer, PhD

Session 7: ePCT Analysis
Jonathan Moyer, PhD

Session 8: Pilot and Feasibility Testing
Beda Jean-Francois, PhD

Session 9: Ethical and Regulatory Oversight Considerations
Stephanie Morain, PhD, MPH

Session 10: Writing a Compelling Grant Application
Beda Jean-Francois, PhD

Session 11: ePCTs in Context: Small Group Work and Panel Discussion With NIH Collaboratory Trials Investigators
Moderator: Stephanie Morain, PhD, MPH
*This session includes case study presentations.

Closing Remarks
Emily O'Brien, PhD

 

Case Studies

Examples from the NIH Collaboratory Trials

AIM-CP: Adapting and Implementing a Nurse Care Management Model to Care for Rural Patients With Chronic Pain (Sebastian Tong, MD, MPH)

BeatPain Utah: Nonpharmacologic Pain Management in Federally Qualified Health Centers Primary Care Clinics (Julie Fritz, PhD, PT)

Chat 4 Heart Health: Using Artificially Intelligent Text Messaging Technology to Improve American Heart Association’s Life’s Essential 8 Health Behaviors (Michael Ho, MD, PhD)

NOHARM: Nonpharmacological Options in Post-operative Hospital Based and Rehabilitation Pain Management Pragmatic Trial (Andrea Cheville, MD, MSCE)

Nudge: Personalized Patient Data and Behavioral Nudges to Improve Adherence to Chronic Cardiovascular Medications (Michael Ho, MD, PhD)

November 20, 2024 Virtual Onboarding Meeting: LungSMART

NIH Pragmatic Trials Collaboratory Onboarding Meeting

November 20, 2024
Virtual

Purpose

Welcome and hear from our new NIH Collaboratory Trial; provide introductions and an overview of the NIH Pragmatic Trials Collaboratory; hear from the Core Working Groups; and engage in discussion.

Welcome and Opening Remarks
Lesley Curtis
Beda Jean-Francois

Overview of the NIH Pragmatic Trials Collaboratory and a Cooperative Agreement
Beda Jean-Francois

Working With the NIH Collaboratory Coordinating Center
Lesley Curtis

Brief Introduction to the Core Working Groups

New UG3 NIH Collaboratory Trial Overview
Population Health Management Approaches to Increase Lung Cancer Screening in Community Health Centers (LungSMART)
David Wetter
Guilherme Del Fiol
Kensaku Kawamoto

Open Discussion
Lesley Curtis

Closing Remarks
Lesley Curtis
Beda Jean-Francois

October 24, 2024 Virtual Onboarding Meeting: APA-SM

NIH Pragmatic Trials Collaboratory Onboarding Meeting

October 24, 2024
Virtual

Purpose

Welcome and hear from our new NIH Collaboratory Trial; provide introductions and an overview of the NIH Pragmatic Trials Collaboratory; hear from the Core Working Groups; and engage in discussion.

Welcome and Opening Remarks
Wendy Weber, ND, PhD, MPH
Lesley Curtis, PhD

Overview of the NIH Pragmatic Trials Collaboratory and a Cooperative Agreement
Wendy Weber

Working With the NIH Collaboratory Coordinating Center
Lesley Curtis, PhD

Brief Introduction to the Core Working Groups

Prevention and Management of Chronic Pain in Rural Populations
Karen Kehl

New UG3 NIH Collaboratory Trial Overview
Jennifer Kawi
Hulin Wu
Jane Bolin

Open Discussion
Lesley Curtis

Closing Remarks
Wendy Weber
Lesley Curtis

Going From Zero to 100: Generating Evidence Through Pragmatic Research to Address Pressing Healthcare Issues: NIH-Hosted Workshop (July 2024)

Posted on by dcridigital

July 15-16, 2024: This 2-day workshop focused on the preparatory actions researchers can undertake in the planning and application phase (Phase Zero) to ensure pragmatic clinical trials yield actionable evidence for a variety of settings. Key aspects include formulating the right research question and engaging with patients, funders, and healthcare system leaders. The workshop also addressed challenges in initiating trials across diverse settings, such as navigating data systems, site diversification, and reducing administrative burdens.

Agenda

Workshop Description

Workshop Summary

Videocast Recording: Day 1

Videocast Recording: Day 2

Agenda and Slides

Day 1: July 15

Welcome and Introduction

Wendy Weber, ND, PhD, MPH
Helene Langevin, MD

Session 1: Phase Zero: Getting the Research Question Right

Moderator: Kevin Weinfurt, PhD

Panel:

Session 2: Engagement as the Cornerstone in Pragmatic Research

Moderator: Gregory Simon, MD

Panel:

Summary and Concluding Remarks

Lesley Curtis, PhD
Gregory Simon, MD
Wendy Weber, ND, PhD, MPH
Kevin Weinfurt, PhD

Day 2: July 16

Welcome and Introduction

Wendy Weber, ND, PhD, MPH
Helene Langevin, MD

Keynote: Connecting Lab, Clinic and Community: Communities Advancing Research Equity (CARE) for Health™

Monica Bertagnolli, MD

Session 3: How to Use Data From Disparate Data Systems

Moderator: Keith Marsolo, PhD

Panel:

Session 4: Retrofitting, Reimagining, and Redesigning Health Care Systems to Reach Populations Most Affected by Health Inequities

Moderator: Rosa Gonzalez-Guarda, PhD, MPH, RN

Panel:

Session 5: Overcoming Administrative Burden in Pragmatic Research

Moderator: Adrian Hernandez, MD, MHS

Panel:

Summary and Concluding Remarks

Lesley Curtis, PhD
Rosa Gonzalez-Guarda, PhD, MPH, RN
Adrian Hernandez, MD, MHS
Keith Marsolo, PhD
Wendy Weber, ND, PhD, MPH

Patient-Centered Research in Real-World Settings: Essentials of Embedded Pragmatic Clinical Trials Workshop: Society for Clinical Trials (May 2024)

Posted on by Lauren Stewart

May 19, 2024: The NIH Pragmatic Trials Collaboratory hosted a preconference workshop, "Patient-Centered Research in Real-World Settings: Essentials of Embedded Pragmatic Clinical Trials,” at the 45th Annual Meeting of the Society for Clinical Trials in Boston. This training workshop introduces concepts in the design and implementation of embedded pragmatic clinical trials (ePCTs), and provides firsthand ePCT experiences and case studies from the NIH Collaboratory Trials.

Agenda
Speaker Biographies
Program Overview
Participant Guide

Agenda and Slides

Welcome and Introduction
Emily O'Brien, PhD

Session 1: What Are Embedded PCTs (ePCTs)?
Wendy Weber, ND, PhD, MPH

Session 2: Engaging and Aligning With Health System and Community Partners
Emily O'Brien, PhD

Session 3: ePCT Design and Analysis
Jonathan Moyer, PhD

Session 4: Measuring Outcomes
Angelo Volandes, MD, MPH

 

Session 5: Overview of NIH Collaboratory Trials
*This presentation contains case studies

Session 6: ePCTs in Context Part 1: Small Group Work
Emily O'Brien, PhD

Session 7: ePCTs in Context Part 2: Panel Discussion with NIH Collaboratory Trial PIs
Moderator: Emily O'Brien, PhD
Panel: Vincent Mor, PhD; Angelo Volandes, MD, MPH

Closing Remarks
Emily O'Brien, PhD; Wendy Weber, ND, PhD, MPH

 

 

Case Studies

Examples from NIH Collaboratory Trials: