January 12, 2026: Enhanced Acupuncture Strategy Found to Be Cost-Saving in Older Adults With Chronic Low Back Pain

Logo for the BackInAction trialAn economic evaluation from the BackInAction trial found that an enhanced course of acupuncture for older adults with chronic low back pain was cost-saving from both the Medicare and healthcare sector perspectives.

The article appears in the upcoming issue of Spine.

In a previously published report, the BackInAction research team established that acupuncture significantly improved pain and disability in patients aged 65 years and older. The new analysis shows the treatment also provides significant value to the healthcare system.

The cost-effectiveness analysis, led by Patricia Herman of the RAND Corporation, analyzed data for 672 participants across 3 large healthcare systems. The study compared 3 treatment strategies: a standard 12 -week course of acupuncture plus usual medical care; standard acupuncture enhanced with up to 6 maintenance sessions plus usual care; and usual care alone.

The research team found that enhanced acupuncture reduced annual back pain–related healthcare costs by an average of $491 per participant and reduced Medicare-reimbursed costs by $421 per participant compared with usual care alone. The savings were primarily driven by a significant reduction in non-acupuncture healthcare utilization.

BackInAction, an NIH Collaboratory Trial, was led by co–principal investigators Lynn DeBar of the Kaiser Permanente Center for Health Research and Andrea Cook of the Kaiser Permanente Washington Health Research Institute.

Read the full report.

Beyond financial savings, participants in the enhanced acupuncture group experienced:

  • Significant gains in quality-adjusted life-years, a standard measure of health-related quality of life
  • An 18.5 percentage-point increase in the number of participants achieving a clinically meaningful improvement in their disability scores

While standard acupuncture was slightly more expensive than usual care, the strategy’s incremental cost-effectiveness ratio of approximately $53,000 per quality-adjusted life-year suggests it may be cost-effective from the perspectives of Medicare and the healthcare sector.

The BackInAction team’s findings are particularly relevant in the context of the Medicare program’s decision in 2020 to begin covering acupuncture for chronic low back pain. The study suggests that the current Medicare benefit, which includes maintenance sessions, aligns with the most cost-effective and beneficial care for this population.

By including a variety of healthcare settings and older adults with multiple medical conditions, this pragmatic clinical trial’s results are intended to be highly generalizable and to inform future treatment policies for the millions of older people in the United States who experience chronic pain.

BackInAction was supported within the NIH Pragmatic Trials Collaboratory through the NIH HEAL Initiative by a grant from the National Center for Complementary and Integrative Health. Learn more about BackInAction.

September 15, 2025: In BackInAction Pragmatic Trial, Acupuncture Improved Back Pain–Related Disability in Older Adults

Headshots of Dr. Lynn DeBar and Dr. Andrea Cook
Dr. Lynn DeBar and Dr. Andrea Cook, co–principal investigators for BackInAction

Older patients with chronic low back pain who receive acupuncture treatment have greater improvements in pain and disability compared with patients who receive usual care alone, according to the BackInAction trial.

The results of the study were published online in JAMA Network Open.

BackInAction, an NIH Collaboratory Trial, compared standard and enhanced courses of acupuncture with usual care alone in adults aged 65 years and older with chronic low back pain. Previous studies found acupuncture to be a safe and effective treatment for chronic low back pain in adults, and the American College of Physicians recommends the treatment as first-line therapy. However, few studies, and no large-scale randomized trials, have examined the safety and efficacy of acupuncture in older adults specifically.

“We worked hard to involve adults in multiple regions of the country so that participant demographics were consistent with the US census for older adults,” Lynn DeBar told the NIH. “And we worked with licensed acupuncturists in the community, who are most likely to deliver these services,” she said. DeBar is a senior investigator at the Kaiser Permanente Center for Health Research and a co–principal investigator for BackInAction.

The study team randomly assigned 800 patients to 1 of 3 groups: (1) a standard 12-week course of acupuncture plus usual medical care; (2) standard acupuncture enhanced with 4 to 6 maintenance sessions plus usual care; or (3) usual care alone. The study was conducted in 4 healthcare systems in the Pacific Northwest, Northern California, and New York, including a network of federally qualified health centers in an urban setting, 2 integrated health insurance and care delivery systems serving broad geographic regions, and a fee-for-service system serving a relatively urban and suburban population.

Logo for the BackInAction trial

At 6 months and 12 months after treatment, patients in both the standard and enhanced acupuncture groups experienced significantly greater reductions in pain and pain-related disability than patients in the usual care group. The improvements did not differ significantly between the standard and enhanced courses of acupuncture.

Read the full article.

“Older adults often are dealing with other medical problems in addition to back pain,” said co–principal investigator Andrea Cook, senior biostatistics investigator at the Kaiser Permanente Washington Health Research Institute. “Acupuncture offers a less invasive option that has a better safety profile than a lot of the common treatments for back pain in older adults,” she said.

BackInAction is supported within the NIH Pragmatic Trials Collaboratory through the NIH HEAL Initiative by a grant from the National Center for Complementary and Integrative Health. Learn more about BackInAction.

May 7, 2025: Results of BackInAction Pragmatic Trial of Acupuncture in Low Back Pain, in This Week’s PCT Grand Rounds

Headshots of Dr. Andrea Cook, Dr. Lynn DeBar, and Dr. Patricia Herman
Dr. Andrea Cook, Dr. Lynn DeBar, and Dr. Paricia Herman

In this Friday’s PCT Grand Rounds, Andrea Cook, Lynn DeBar, and Patricia Herman will present “A Policy-Relevant Pragmatic Trial on Acupuncture Effectiveness for Low Back Pain in Older Adults: Clinical and Cost Outcomes and Lessons Learned.”

The Grand Rounds session will be held on Friday, May 9, 2025, at 1:00 pm eastern.

The speakers will present the results of BackInAction, an NIH Collaboratory Trial. BackInAction compared standard and advanced courses of acupuncture with usual care for older adults with chronic low back pain.

Cook is a senior biostatistics investigator at the Kaiser Permanente Washington Health Research Institute; DeBar is a distinguished investigator at the Kaiser Permanente Center for Health Research; and Herman is a senior behavioral scientist at RAND, codirector of the RAND Research Across Complementary and Integrative Health Institutions (REACH) Center, and a professor of policy analysis at the RAND School of Public Policy.

Join the online meeting.

June 11, 2024: Many Older Participants in Acupuncture Research Have Prior Acupuncture Experience, BackInAction Data Suggest

Headshots of Dr. Andrea Cook and Dr. Lynn DeBar
Dr. Andrea Cook and Dr. Lynn DeBar, principal investigators of BackInAction

Many older adults who participate in acupuncture research may have prior experience with acupuncture, according to an analysis of data from the BackInAction trial. The finding has implications for the design and conduct of future pragmatic clinical trials involving acupuncture.

BackInAction, an NIH Collaboratory Trial, is testing strategies for the delivery of acupuncture to older patients with chronic low back pain. Learn more about BackInAction.

The researchers used data from baseline interviews at 1 of 4 trial sites to characterize participants’ prior experience with acupuncture and their views toward the practice. They also compared clinical and sociodemographic characteristics between participants who had acupuncture experience and those who did not.

Nearly two-thirds of the participants reported they had previously received acupuncture treatment, mostly for pain-related care. There were no significant differences in clinical and sociodemographic characteristics between participants with prior acupuncture and those without. The researchers concluded that it may be more feasible for future pragmatic trials to use an expanded definition of “acupuncture-naïve” in inclusion criteria.

Read the full report.

BackInAction is supported through the NIH HEAL Initiative by a grant administered by the National Center for Complementary and Integrative Health (NCCIH).

November 1, 2023: Special Biostatistics Series Continues With Complex Clustering in Pragmatic Trials

In this Friday’s PCT Grand Rounds, Jonathan Moyer of the NIH Office of Disease Prevention will continue our special series, Advances in the Design and Analysis of Pragmatic Clinical Trials, with his presentation, “The Perils and Pitfalls of Complex Clustering in Pragmatic Trials.” The session will be held on Friday, November 3, at 1:00 pm eastern and will be moderated by Andrea Cook.

Moyer is a statistician in the NIH Office of Disease Prevention. He is a longtime member of the NIH Pragmatic Trials Collaboratory’s Biostatistics and Study Design Core. This session’s moderator, Andrea Cook, is a senior biostatistics investigator in the Kaiser Permanente Washington Health Research Institute.

Join the online meeting.

This special Grand Rounds series will include additional moderated webinar discussions that bring together biostatisticians, clinical trials methodologists, and investigators to discuss challenges and share lessons learned in the design, implementation, and analysis of pragmatic trials. Download the series flyer and see the full schedule below.

All sessions are free and open to the public; no registration is required.

Grand Rounds Biostatistics Series November 3, 2023: The Perils and Pitfalls of Complex Clustering in Pragmatic Trials (Jonathan Moyer, PhD; Moderator: Andrea Cook, PhD)

Speaker: Jonathan C. Moyer, PhD
Statistician, NIH Office of Disease Prevention

Moderator: Andrea J. Cook, PhD
Senior Biostatistics Investigator, Kaiser Permanente Washington Health Research Institute

Topic: The Perils and Pitfalls of Complex Clustering in Pragmatic Trials

Date: Friday, November 3, 2023, 1:00-2:00 p.m. ET

To join the online meeting:

Click the Zoom Meeting link below:

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Meeting ID: 973 4017 4674
Passcode: 953285

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