April 30, 2025: The FRESH-UP Study of Fluid Restriction in Heart Failure, in This Week’s PCT Grand Rounds

Headshot of Dr. Roland RJ van KimmenadeIn this Friday’s PCT Grand Rounds, Roland RJ van Kimmenade will present “Fluid Restriction in Heart Failure Versus Liberal Fluid Uptake: The FRESH-UP Study.”

The Grand Rounds session will be held on Friday, May 2, 2025, at 1:00 pm eastern.

Van Kimmenade is a cardiologist at Radboud University Medical Center in Nijmegen, Netherlands.

Join the online meeting.

April 23, 2025: In This Week’s PCT Grand Rounds, Automated Response Technology in EMR and Physician-Patient Communication

Headshot of Dr. Ming Tai-SealeIn this Friday’s PCT Grand Rounds, Ming Tai-Seale of the University of California, San Diego, will present “Automated Response Technology Integrated Into EMR and Physician-Patient Communication.”

The Grand Rounds session will be held on Friday, April 25, 2025, at 1:00 pm eastern.

Tai-Seale is professor and vice chair of research in the Department of Family Medicine at the University of California, San Diego, and director of the UCSD Learning Health Systems Science Center.

Join the online meeting.

April 16, 2025: In This Week’s PCT Grand Rounds, Colchicine and Spironolactone After Myocardial Infarction

Headshot of Dr. Sanjit Jolly
Dr. Sanjit Jolly

In this Friday’s PCT Grand Rounds, Sanjit Jolly of McMaster University will present “Colchicine and Spironolactone Post-MI: A Review of the Late-Breaking Results of the CLEAR OASIS 9 Trial.”

The Grand Rounds session will be held on Friday, April 18, 2025, at 1:00 pm eastern.

Jolly is an interventional cardiologist at Hamilton Health Sciences and the Stuart Connolly Chair in Cardiology and a professor of medicine at McMaster University.

Join the online meeting.

April 9, 2025: Healey Platform Trial Examines Pridopidine in ALS, in This Week’s PCT Grand Rounds

Headshot of Dr. Jeremy ShefnerIn this Friday’s PCT Grand Rounds, Jeremy Shefner of the Barrow Neurological Institute will present “A Phase 2 Trial of Pridopidine in ALS, Studied as a Regimen With the Healey Platform Trial.”

The Grand Rounds session will be held on Friday, April 11, 2025, at 1:00 pm eastern.

Shefner is a professor of neurology at the Barrow Neurological Institute in Phoenix, Arizona.

Join the online meeting.

March 26, 2025: GPT-4–Based Plain Language Translation of Clinical Notes for Patients, in This Week’s PCT Grand Rounds

Headshots of Dr. Matthew Engelhard and Anivarya Kumar
Dr. Matthew Engelhard and Anivarya Kumar

In this Friday’s PCT Grand Rounds, Matthew Engelhard and Anivarya Kumar of Duke University will present “A Cross-Sectional Study of GPT-4–Based Plain Language Translation of Clinical Notes to Improve Patient Comprehension of Disease Course and Management.”

The Grand Rounds session will be held on Friday, March 28, 2025, at 1:00 pm eastern.

Engelhard is an assistant professor of biostatistics and bioinformatics and Kumar is a fourth-year medical student at Duke University.

Join the online meeting.

March 19, 2025: Use of Generative AI in Clinical Trials, in This Week’s PCT Grand Rounds

Headshot of Dr. Alexander "AJ" Blood
Dr. Alexander “AJ” Blood

In this Friday’s PCT Grand Rounds, Alexander J. “AJ” Blood of Harvard Medical School and Brigham and Women’s Hospital will present “Generative Artificial Intelligence in Clinical Trials: A Driver of Efficiency and Democratization of Care.”

The Grand Rounds session will be held on Friday, March 21, 2025, at 1:00 pm eastern.

Blood is an instructor of medicine and associate director of the Accelerator for Clinical Transformation Research Group at Harvard Medical School and a cardiologist and intensivist at Brigham and Women’s Hospital.

Join the online meeting.

March 12, 2025: In This Week’s PCT Grand Rounds, Spillover as a Potential Source of Bias in Pragmatic Trials

Headshot of Sean Mann
Sean Mann

In this Friday’s PCT Grand Rounds, Sean Mann of RAND will present “Spillover Due to Constraints on Care Delivery: A Potential Source of Bias in Pragmatic Clinical Trials.”

The Grand Rounds session will be held on Friday, March 14, 2025, at 1:00 pm eastern.

Mann is a senior policy analyst at RAND.

Join the online meeting.

March 5, 2025: A Kidney Action Team for Patients With Acute Kidney Injury, in This Week’s PCT Grand Rounds

Headshot of Dr. F. Perry Wilson
Dr. F. Perry Wilson

In this Friday’s PCT Grand Rounds, F. Perry Wilson of Yale University will present “A Trial of a “Kidney Action Team” for Hospitalized Patients with Acute Kidney Injury.”

The Grand Rounds session will be held on Friday, March 7, 2025, at 1:00 pm eastern.

Wilson is an associate professor of medicine and public health and the director of the Clinical and Translational Research Accelerator at Yale University.

Join the online meeting.

February 26, 2025: BEST-ICU Trial to Be Featured in This Week’s PCT Grand Rounds

Headshots of Dr. Michele Balas and Dr. Eduard Vasilevskis
Dr. Michele Balas and Dr. Eduard Vasilevskis, principal investigators of BEST-ICU

In this Friday’s PCT Grand Rounds, Michele Balas and Ed Vasilevskis will present “Behavioral Economic and Staffing Strategies To Increase Adoption of the ABCDEF Bundle in the Intensive Care Unit (BEST-ICU): Protocol, Challenges, and Major Updates.”

The Grand Rounds session will be held on Friday, February 28, 2025, at 1:00 pm eastern.

BEST-ICU, an NIH Collaboratory Trial supported by the National Heart, Lung, and Blood Institute, is evaluating 2 strategies grounded in behavioral economics theory and implementation science to increase ABCDEF bundle adoption in the intensive care unit and improve care for critically ill adults across a variety of healthcare systems. The ABCDEF bundle is a multicomponent, evidence-based intervention to improve team-based care. Learn more about BEST-ICU.

Balas is the Dorothy Hodges Olson Distinguished Professor of Nursing and the associate dean of research at the University of Nebraska Medical Center College of Nursing. Vasilevskis is a professor of medicine at the University of Wisconsin-Madison.

Join the online meeting.

February 19, 2025: Texting for Behavior Change to Improve Chronic Care Management, in This Week’s PCT Grand Rounds

Chat 4 Heart Health logoIn this Friday’s PCT Grand Rounds, Michael Ho and Sheana Bull will present “Texting for Behavior Change: Lessons Learned Across 2 Interventions to Improve Chronic Care Management.”

The Grand Rounds session will be held on Friday, February 21, 2025, at 1:00 pm eastern.

This Grand Rounds session will report the results of Chat 4 Heart Health, an NIH Collaboratory Trial. The trial evaluated the comparative effectiveness of 3 text messaging delivery strategies that have been shown to improve individuals’ self-management health behaviors. The presenters will also share insights from Nudge, another NIH Collaboratory Trial, which tested a variety of text messaging strategies to encourage patients to refill their cardiovascular medications.

Ho is a senior clinician investigator at Kaiser Permanente Colorado’s Institute for Health Research. Bull is a professor of community and behavioral health at the Colorado School of Public Health.

Join the online meeting.