ARCHIVED PAGE
Archived on July 31, 2025. Go to the latest version.
ARCHIVED – What is a Pragmatic Clinical Trial
Section 6
Key Considerations for PCTs – ARCHIVED
Planning an ePCT often requires different approaches to study design, stakeholder engagement, start-up, data collection, data analysis, ethical oversight, and dissemination than do traditional RCTs (O’Rourke et al. 2015). To provide expertise and support to the NIH Collaboratory Trials, several working groups, or Cores, were established to assist study teams as they navigate from planning to implementation. The webpage for each Core listed below provides information and links to multiple resources including webinars, publications, and white papers that reflect the knowledge, insight, and best practices acquired by the Cores in collaboration with the NIH Collaboratory Trials.
SECTIONS
sections
- Why Are We Talking About Pragmatic Trials? – ARCHIVED
- The Embedded Pragmatic Clinical Trial Ecosystem – ARCHIVED
- Differentiating Between RCTs, PCTs, and Quality Improvement Activities – ARCHIVED
- Pragmatic Elements: An Introduction to PRECIS-2- ARCHIVED
- PRECIS-2 Case Study – ARCHIVED
- Key Considerations for PCTs – ARCHIVED
- Additional Resources – ARCHIVED
REFERENCES
O’Rourke PP, Carrithers J, Patrick-Lake B, et al. 2015. Harmonization and streamlining of research oversight for pragmatic clinical trials. Clin Trials. 12:449–456. doi:10.1177/1740774515597685. PMID: 26374678.
current section : Key Considerations for PCTs – ARCHIVED
- Why Are We Talking About Pragmatic Trials? – ARCHIVED
- The Embedded Pragmatic Clinical Trial Ecosystem – ARCHIVED
- Differentiating Between RCTs, PCTs, and Quality Improvement Activities – ARCHIVED
- Pragmatic Elements: An Introduction to PRECIS-2- ARCHIVED
- PRECIS-2 Case Study – ARCHIVED
- Key Considerations for PCTs – ARCHIVED
- Additional Resources – ARCHIVED