The Health Care Systems (HCS) Interactions Core of the NIH Collaboratory has created a new guidance document: Resources for Frequently Asked Questions. The document compiles common questions from researchers and points to resources that provide potential solutions, including Living Textbook chapters and journal articles. The topics include evaluation strategies, anticipating and adapting to changes, dissemination and implementation, and stakeholder engagement.

The NIH Collaboratory Core Working Groups have created a series of handouts to help investigators conduct pragmatic trials:

• From the Biostatistics and Study Design Core:
  • The Intraclass Correlation Coefficient Cheat Sheet provides an introductory description of the intraclass correlation coefficient (ICC).
• From the Electronic Health Records Core:
  • The Onboarding Data and Resource Sharing Informational Document provides information on data and resource sharing.
  • The Assessing Quality of Clinical Data for PCTs (Brief Version) highlights recommendations for assessing the quality of data generated from routine patient care for use in PCTs.
• From the Ethics and Regulatory Core
  • Engagement in Research for Pragmatic Clinical Trials describes 3 categories of individuals in relationship to the research activity: research subjects, study team members, and service providers.