Core goal: Support implementation-related research aims in pragmatic clinical trials to promote the uptake and sustainability of effective interventions in routine practice, with the aim of improving population health.

The Implementation Science Core will provide technical support and pragmatic trial expertise for NIH Collaboratory Trials with a specific focus on innovative dissemination and implementation science approaches. Improved dissemination and implementation of evidence-based practices requires the careful building of relationships with study teams early on. Integrating implementation frameworks and methods into the study design is essential for post-trial implementation success. The Implementation Science Core will meet regularly with NIH Collaboratory Trial study leaders from the start of their projects to help plan and work through any implementation related issues.

Pragmatic clinical trials have great potential to translate interventions into real-world practice. The Implementation Science Core will work to ensure that effective NIH Collaboratory Trial interventions achieve maximum impact, are scalable, and can be sustained in healthcare systems long-term.