The Logistics of Using a Single IRB
Section 1
Introduction
The main goal of using a single institutional review board (IRB), or sIRB, for multisite research is to streamline the review process by eliminating duplicative reviews at the clinical trial sites. There has been a dramatic increase in the use of an sIRB review model in response to the 2016 NIH policy requiring sIRB review for NIH-funded multisite research (NIH 2016) and the requirement for sIRB review of cooperative research set forth in the revised Common Rule (Office of Human Research Protections 2017).
SECTIONS
REFERENCES
NIH. (2016). Final NIH Policy on the Use of a Single Institutional Review Board for Multi-Site Research. NOT-OD-16-094. https://grants.nih.gov/grants/guide/notice-files/NOT-OD-16-094.html
Office of Human Research Protections. (2017). Federal Policy for the Protection of Human Subjects. Final rule. Fed Regist. 82(12):7149-274. PMID: 28106360.
ACKNOWLEDGMENTS
Megan K. Singleton, JD, MBE, CIP, reviewed previous versions of this chapter.