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NIH Collaboratory
Living Textbook of
Pragmatic Clinical Trials

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Rethinking Clinical Trials

A Living Textbook of Pragmatic Clinical Trials

  • Design
    • What is a Pragmatic Clinical Trial?
    • Decentralized Pragmatic Clinical Trials
    • Developing a Compelling Grant Application
    • Experimental Designs and Randomization Schemes
    • Endpoints and Outcomes
    • Analysis Plan
    • Using Electronic Health Record Data
    • Building Partnerships and Teams to Ensure a Successful Trial
    • Intervention Delivery and Complexity
    • Patient Engagement
  • Data, Tools & Conduct
    • Assessing Feasibility
    • Acquiring Real-World Data
    • Assessing Fitness-for-Use of Real-World Data
    • Study Startup
    • Participant Recruitment
    • Monitoring Intervention Fidelity and Adaptations
    • Patient-Reported Outcomes
    • Clinical Decision Support
    • Mobile Health
    • Electronic Health Records–Based Phenotyping
    • Navigating the Unknown
  • Dissemination & Implementation
    • Data Sharing and Embedded Research
    • Dissemination Approaches for Different Audiences
    • Implementation
    • End-of-Trial Decision-Making
  • Ethics & Regulatory
    • Privacy Considerations
    • Identifying Those Engaged in Research
    • Collateral Findings
    • Consent, Disclosure, and Non-Disclosure
    • Data and Safety Monitoring
    • Ethical Considerations of Data Sharing in Pragmatic Clinical Trials
    • Ethics for AI and ML
    • IRB Responsibilities and Procedures

FAQ

CHAPTER SECTIONS

Building Partnerships and Teams to ensure a successful trial


Section 9


FAQ

Expand Contributors

James Fraser
Rachael Moloney, MHS
Ellen Tambor, MA
Leah Tuzzio, MPH

Contributing Editor
Karen Staman, MS
Gina Uhlenbrauck

Frequently Asked Questions

Question

Answer

What if the health system leadership is resistant to your proposed intervention? What do you do when the providers don’t think the issue you want to study is important? When engaging health system partners, frame your research question to show how knowing the answer will benefit their priorities. Align your ideas with their mission, promote cost-saving and enhancement of patients’ needs. It’s all about head, heart, and heat. If you can get to the place where the system leaders own it, then they will want to see the results. Set the expectation for partners to take pride in doing research, understand what they don’t know, and be a part of the team.
What do you do when there is a real conflict in priorities? How do you wrestle divergence of opinions with different priorities? Partner with a local champion. There are multiple ways to find a champion for your research. It could be frontline clinicians and staff or health system leadership.
Nobody wants to volunteer or give up anything for free, and it takes resources to generate a pilot that will produce evidence to get the grant. How do I get past these roadblocks? Fully understand what the possible wins are, and frame the project around what the health system will gain. The rewards could be reductions in costs, increased patient satisfaction, or alignment with organizational goals and the mission of the health system.

Previous Section

SECTIONS

CHAPTER SECTIONS

sections

  1. Introduction
  2. Engagement Across Settings and Populations
  3. Deciding Who to Engage
  4. Partner Engagement Throughout the PCT Life Cycle
  5. Advice From Healthcare System Leadership
  6. Embedded ePCT Team Composition
  7. Learning Health Systems and Embedded Clinical Trials
  8. Framework for Health Systems to Assess PCT Participation
  9. FAQ


Version History

Published December 15, 2018

current section :

FAQ

  1. Introduction
  2. Engagement Across Settings and Populations
  3. Deciding Who to Engage
  4. Partner Engagement Throughout the PCT Life Cycle
  5. Advice From Healthcare System Leadership
  6. Embedded ePCT Team Composition
  7. Learning Health Systems and Embedded Clinical Trials
  8. Framework for Health Systems to Assess PCT Participation
  9. FAQ

Citation:

Building Partnerships and Teams to ensure a successful trial: FAQ. In: Rethinking Clinical Trials: A Living Textbook of Pragmatic Clinical Trials. Bethesda, MD: NIH Pragmatic Trials Collaboratory. Available at: https://rethinkingclinicaltrials.org/chapters/engaging-stakeholders/faq/. Updated July 16, 2025. DOI: 10.28929/100.

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