March 3, 2020: Healthcare System Leaders Give Advice to Pragmatic Trial Investigators

In a new section of the Living Textbook on Building Partnerships to Ensure a Successful Trial, Kenneth Sands, the chief epidemiologist and chief patient safety officer at HCA, and Jonathan Perlin, the chief medical officer and president of clinical services at HCA, offer advice to investigators who wish to conduct pragmatic clinical trials.

“Healthcare systems have constrained bandwidth, and participating in learning activities involves significant costs and challenges: there are direct costs but also intangible costs, which can be substantial, such as personnel time, IT time, distraction of clinical staff, and the potential for supply chain issues.” — Advice from Healthcare System Leadership

The authors establish principles of partnership that include establishing and maintaining a durable partnership, selecting topics of mutual interest, and giving precedence to operational imperatives.

For more, see the article “Real-World Advice for Generating Real-World Evidence” in NEJM Catalyst.