Matthew T. Roe, MD, MHS, Principal Investigator of ADAPTABLE, Duke Clinical Research Institute
Holly Robertson, PhD, Project Leader for ADAPTABLE, Duke Clinical Research Institute
Madelaine Faulkner, MPH, Project Director of Health eHeart Alliance Patient-Powered Research Network
Adaptors (Patient Partners): Linda Brown of the Mid-South Clinical Data Research Network (CDRN), Ken Gregoire of the REACHnet CDRN, and Tom McCormick of the PaTH CDRN
ADAPTABLE, the Aspirin Study: Embracing Patient-Partnered Research
Patient engagement; Patient-centric research; ADAPTABLE; Aspirin study; Comparative effectiveness research; CER; Outcomes research; Informed consent; Patient recruitment; Pragmatic clinical trial; Clinical research; Real-world evidence
- ADAPTABLE (Aspirin Dosing: A Patient-centric Trial Assessing Benefits and Long-Term Effectiveness) is a 3-year pragmatic clinical trial that will compare the effectiveness of two different daily doses of aspirin widely used to prevent heart attacks and strokes in individuals living with heart disease.
- “Adaptors” are patient representatives working alongside researchers in all aspects of the ADAPTABLE study. They helped design the protocol, informed consent form, study portal, and study recruitment materials. Adaptors will be integral in disseminating study updates and results to other patients and the community.
- “Patient-partnered research is more than participation on a phone call. It involves trust, partnership, and respect. Listening to all perspectives is essential. Effective patient engagement empowers patients and values their experience.
Patients are very interested in having a say about research that matters to them.
What were the most successful strategies for engaging the Adaptors? Could your approach be used to increase patient engagement for disease-agnostic initiatives such as health literacy?
When the trial is finished, how will you disseminate the findings to clinicians and patients? How will the findings be adopted?
What are the considerations for implementing embedded patient engagement in all trials?
For More Information
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@ADAPTABLEstudy, @PCTGrandRounds, @Collaboratory1, @PCORnetwork