Podcast December 5, 2018: Validating a Computable Phenotype: Should Results Change a Trial’s Pre-Specified Primary Outcome? (Gregory E. Simon, MD, MPH, Susan M. Shortreed, PhD)

In this episode of the NIH Collaboratory Grand Rounds podcast, Dr. Lesley Curtis speaks with Dr. Gregory Simon and Dr. Susan Shortreed of the Kaiser Permanente Washington Health Research Institute. In their conversation, Drs. Curtis, Simon, and Shortreed discuss computable phenotypes and if results should change a trial’s pre-specified primary outcome. Drs. Simon and Shortreed explain how they used the Suicide Prevention Outreach Trial (SPOT) to explore this question, the process they followed, and the lessons learned.

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Want to hear more from Dr. Gregory Simon and Dr. Susan Shortreed? View the full Grand Rounds presentation.

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