November 4, 2026: Study Snapshots and Updated Ethics Documentation Available for LungSMART and STEP-2 Trials

New study snapshots and updated ethics and regulatory documentation are now available for the LungSMART and STEP-2 trials. One year into the studies, and after receiving approval to transition to the implementation phase, the research teams reviewed and updated the minutes of their initial consultations with the Ethics and Regulatory Core.

LungSMART and STEP-2 are the first NIH Collaboratory Trials to be supported by grant awards from the National Cancer Institute.

LungSMART

Headshots of LungSMART investigators David Wetter, Guilherme Del Fiol, and Ken Kawamoto
Left to right: LungSMART investigators Drs. David Wetter, Guilherme Del Fiol, and Ken Kawamoto

New resources for LungSMART:

LungSMART, led by Dave Wetter, Guilherme Del Fiol, and Ken Kawamoto of the University of Utah, is testing a combination of text messages, an interactive chatbot, and educational videos delivered by text message to address barriers to completing lung cancer screening among patients receiving care in safety net community health centers. Learn more about LungSMART.

STEP-2

Headshots of Drs. Rachel Winer, Amanda Petrik, and Jasmin Tiro
Left to right: STEP-2 investigators Drs. Rachel Winer, Amanda Petrik, and Jasmin Tiro

New resources for STEP-2:

STEP-2, led by Rachel Winer of the University of Washington, Amanda Petrik of the Kaiser Permanente Center for Health Research, and Jasmin Tiro of the University of Chicago, is evaluating the comparative effectiveness and cost-effectiveness of in-clinic vs mailed distribution of human papillomavirus (HPV) self-collect kits to improve cervical cancer screening rates among patients receiving care in community health centers. Learn more about STEP-2.