The NIA IMPACT Collaboratory announced a request for applications for its 2025 Demonstration Projects Grants Program.

The program will fund up to 2 Demonstration Projects, each providing up to $800,000 in total direct costs over a 24-month period. The awards will support full-scale embedded pragmatic clinical trials. Projects must evaluate the effectiveness of nonpharmacological interventions embedded within healthcare systems for people living with dementia and their care partners.

The required letters of intent are due by November 13. More information is available on the IMPACT Collaboratory website.

More than 5 million Americans are living with Alzheimer disease and related dementias. They are particularly vulnerable to receiving uncoordinated and poor-quality care, which contributes to adverse health outcomes and misuse of resources. The mission of the IMPACT Collaboratory is to advance care for persons with dementia and their caregivers in real-world settings by building national capacity to conduct pragmatic clinical trials that test interventions embedded in healthcare systems.

The NIA IMPACT Collaboratory is supported by a grant from the National Institute on Aging.