The NIH Pragmatic Trials Collaboratory Coordinating Center is pleased to announce that the BEST-ICU trial received approval to transition from the planning phase to the implementation phase of the study. Congratulations to the BEST-ICU principal investigators and study team for reaching this important milestone!
BEST-ICU, an NIH Collaboratory Trial, is a pragmatic trial that aims to develop pragmatic and sustainable strategies to increase the delivery of evidence-based practices that lead to improved care for critically ill adults across a variety of healthcare systems, particularly those serving populations with known health disparities. BEST-ICU will evaluate 2 strategies grounded in behavioral economy theory and implementation science to increase ABCDEF bundle adoption. The ABCDEF bundle is a multicomponent, evidence-based intervention to improve team-based care.
Principal investigators Ed Vasilevskis and Michele Balas spoke recently about the importance of the study at the NIH Pragmatic Trials Collaboratory’s 2024 Annual Steering Committee Meeting.
Vasilevskis is the chief of the Division of Hospital Medicine in the Department of Medicine at the University of Wisconsin School of Medicine and Public Health. Balas is the associate dean of research and the Dorothy Hodges Olson Distinguished Professor of Nursing at the University of Nebraska Medical Center's College of Nursing.
BEST-ICU is supported through a cooperative agreement from the National Heart, Lung, and Blood Institute.