The NIA IMPACT Collaboratory has announced that it will publish a request for applications for large-scale pragmatic clinical trials embedded in healthcare systems to test the effectiveness of care delivery intervention programs for people living with Alzheimer disease and related dementias and/or their care partners. The funding opportunity is expected to be announced in February.

More information from the notice of intent:

Under this mechanism, interventions must be linked to the needs of a health care system and powered to detect a significant difference in the primary outcome between trial arms. The goal of the NIH Collaboratory Trials is to generate evidence on effective care delivery practices that can be expanded and/or implemented in other systems.

The IMPACT Collaboratory will give preference to applications for NIH Collaboratory Trials that address dementia care for populations traditionally marginalized or underrepresented in clinical trials and those that promote health equity. It is anticipated that NIH Collaboratory Trials will be funded for up to $500,000 in direct costs for a maximum of 24-months.

The RFA is expected to be published in February 2021. Stay tuned for updates regarding the release of the RFA, an informational webinar and application deadline. If you have questions related to this funding opportunity, please contact IMPACTcollaboratory@hsl.harvard.edu. We will share additional details as they become available on the website at www.IMPACTcollaboratory.org.

The NIA IMPACT Collaboratory is supported by a grant from the National Institute on Aging. Its mission is to advance care for persons with dementia and their caregivers in real-world settings by building national capacity to conduct pragmatic clinical trials that test interventions embedded in healthcare systems.