How Do Data Sources inform the Choice of Endpoints and Outcomes in Pragmatic Trials?

Description

Pragmatic clinical trials are often dealing with multiple sources of data from more than one health system, EHRs, and multiple payers claims databases. It can be a balancing act in terms of measurement and pragmatism. While patient-reported outcomes are more expensive, and less efficient, they are often the most salient outcomes from a stakeholder perspective, and therefore, important to collect in pragmatic clinical trials.