videos

Building a Study Team for a Pragmatic Clinical Trial

Posted on by terren.green@duke.edu

Building a Study Team for a Pragmatic Clinical Trial

Description

Embedded pragmatic clinical trials require many different kinds of expertise, from the PI and Co-PI and biostatisticians to research assistants, communications specialists and more. It is important to recruit the team before all of the decisions are made and to keep the team engaged for the duration of the trial. This video offers strategies for building your team.

Speaker

Lesley Curtis, PhDHeadshot of Dr. Lesley Curtis
Professor of Population Health Sciences and Medicine, Duke University
Duke Clinical Research Institute
Collaboratory Steering Committee Chair

Related

Building Partnerships and Teams to Ensure a Successful Trial

What Are the “Must Dos” of Writing PCT Grant Applications?

Posted on by Elizabeth Mccamic

What Are the “Must Dos” of Writing PCT Grant Applications?

Description

Dr. Wendy Weber provides suggestions for writing PCT grant applications from the perspective of an application reviewer. Her recommendations include providing strong justifications, ensuring the proposed study is impactful and advances the field, and proposing a study that reduces complexity in the healthcare field.

Speaker

Wendy Weber, ND, PhD, MPH
Branch Chief, Clinical Research Branch
Division of Extramural Research
National Center for Complementary and Integrative Health (NCCIH)

 

Related

What Are Common Pitfalls in Writing PCT Grant Applications?

Is It Important to Explain the Definition of Pragmatic to Grant Reviewers?

What Should I Avoid When Writing PCT Grant Applications?

What Are Some Success Strategies for Writing PCT Grant Applications?

Developing a Compelling Grant Application

Pilot-Testing Interventions in Pragmatic Trials: SPOT Case Study

Posted on by Elizabeth Mccamic

Pilot-Testing Interventions in Pragmatic Trials: SPOT Case Study

Description

In this video, Dr. Greg Simon, PI of the SPOT trial, summarizes pilot testing SPOT as a way of illustrating how pilot testing in ePCTs differs from more conventional randomized trials.

Biography

Photo of Greg SimonGregory Simon, MD, MPH
Senior Investigator, Kaiser Permanente Washington Health Research Institiute
SPOT NIH Collaboratory Trial PI
Health Care Systems Interactions Core Chair
Coordinating Center Leadership

Related

Pilot Testing

How Does Clustering Affect Power and Detectable Difference?

Posted on by Elizabeth Mccamic

How Does Clustering Affect Power and Detectable Difference?

Description

In this video, Dr. Liz Turner walks through an example that illustrates how clustering affects power and detectable difference.

Speaker

Liz Turner, PhD
Associate Professor, Biostatistics and Bioinformatics and Global Health
Biostatistics and Study Design Core Co-Chair

 

Related

What Are the Reasons to Randomize Clusters Instead of Individuals?

What Is Outcome Clustering, and How Can It Affect a Trial?

What Is the Intraclass Correlation Coefficient?

How Do You Estimate the Degree of Clustering for Outcomes?

EHR Pragmatic Innovation Beyond Follow-up in the TSOS Study

Posted on by terren.green@duke.edu

EHR Pragmatic Innovation Beyond Follow-up in the TSOS Study

Description

Dr. Doug Zatzick of the University of Washington describes the unique challenges of using electronic health records in the TSOS study.

Biography

Doug Zatzick, MD
Professor, Department of Psychiatry and Behavioral Sciences, University of Washington School of Medicine

 

 

Related

View the full Grand Rounds video: Experiences From the Collaboratory PCTs

Finding the Right NIH Funding Opportunity

Posted on by terren.green@duke.edu

Finding the Right NIH Funding Opportunity

Description

Dr. Wendy Weber, the NIH Pragmatic Trials Collaboratory Program Official, shares insights about the 27 Institutes and Centers (ICs) across the National Institutes of Health. Each IC has its own budget and will create its own funding applications, based on their area of focus, which can be a disease area, organ system, or stage of life. The matchmaker tool on the NIH RePORTER page can help determine the most appropriate Program Official for a given project.

Speaker

Wendy Weber, ND, PhD, MPH
Branch Chief, Clinical Research Branch
Division of Extramural Research
National Center for Complementary and Integrative Health (NCCIH)

Related

Developing a Compelling Grant Application

 

What Are the Benefits to Standardizing Phenotype Definition?

Posted on by Elizabeth Mccamic

What Are the Benefits to Standardizing Phenotype Definition?

Description

Dr. Rachel Richesson discusses the benefits to standardizing phenotype definitions, which entails reusing and repurposing definitions for different studies. Richesson asserts that this practice allows for greater efficiency across research projects.

Speaker

Rachel Richesson, PhDHeadshot of Rachel Richesson
Professor of Learning Health Sciences, University of Michigan Medical School
Electronic Health Records Core Co-chair

 

Related

What Are the Challenges of Using Data Directly From the EHRs?

What Is A Computable Phenotype?

What Are the Key Factors in Using EHR Data for Endpoints and Outcomes?

Using Electronic Health Record Data in Pragmatic Clinical Trials

Is It Important to Explain the Definition of Pragmatic to Grant Reviewers?

Posted on by Elizabeth Mccamic

Is It Important to Explain the Definition of Pragmatic to Grant Reviewers?

Description

Dr. Wendy Weber discusses the importance of defining what it means to be pragmatic in the context of a specific study and whether or not each element of a study is pragmatic in a PCT grant application.

Speaker

Wendy Weber, ND, PhD, MPH
Branch Chief, Clinical Research Branch
Division of Extramural Research
National Center for Complementary and Integrative Health (NCCIH)

Related

What Are Common Pitfalls in Writing PCT Grant Applications?

What Are the “Must Dos” of Writing PCT Grant Applications?

What Should I Avoid When Writing PCT Grant Applications?

What Are Some Success Strategies for Writing PCT Grant Applications?

Developing a Compelling Grant Application

Guiando Buenas Decisiones: Implementing GGC4H for Spanish-Speaking Families of Young Adolescents

Posted on by Damon Seils

Guiando Buenas Decisiones: Implementing GGC4H for Spanish-Speaking Families of Young Adolescents

Description

Dr. Stacy Sterling of Kaiser Permanente Northern California discusses a pilot study to explore the feasibility of implementing a universal prevention curriculum for Spanish-speaking families of young adolescents, a supplement to GGC4H, an NIH Collaboratory Trial.

Speaker

Headshot of Stacy SterlingStacy Sterling, DrPH, MSW
Kaiser Permanente Division of Research
Co-Director, Center for Addiction and Mental Health Research
Associate Adjunct Professor, UCSF Department of Psychiatry and Behavioral Sciences
Associate Professor, Department of Health Systems Science, Kaiser Permanente Bernard J. Tyson School of Medicine

Related Content

View the full Grand Rounds video