December 11, 2022: The NIH Pragmatic Trials Collaboratory hosted a Pre-Conference Workshop at the 15th AcademyHealth Annual Conference on the Science of Dissemination and Implementation in Health. This training workshop introduces concepts in the design, conduct, and implementation of embedded pragmatic clinical trials (ePCTs), and provides firsthand ePCT experiences and case studies from the NIH Pragmatic Trials Collaboratory Trials.
Agenda and Slides
Morning Sessions
Welcome and Introduction
Wendy Weber, ND, PhD, MPH
Session 1: What are Embedded Pragmatic Clinical Trials (ePCTs)?
Wendy Weber, ND, PhD, MPH
Session 2: Engaging Stakeholders & Aligning with Health System Partners
Emily O’Brien, PhD
Session 3: Objectives and Trial Design: An Overview of Hybrid Designs
Emily O’Brien, PhD
Session 4: Measuring Outcomes
Emily O’Brien, PhD
Session 5: ePCT Design
David Murray, PhD
Session 6: ePCT Analysis
David Murray, PhD
Session 7: ePCTs in Context: Panel Discussion with NIH Collaboratory Trial PIs
Moderator: Emily O’Brien, PhD
*This session includes the Case Study Presentations.
Afternoon Sessions
Session 8: Pilot & Feasibility Testing
Wendy Weber, ND, PhD, MPH
Session 9: Ethical & Regulatory Oversight Considerations
Stephanie Morain, PhD, MPH
Session 10: ePCTs in Context: Panel Discussion with NIH Collaboratory Trial PIs
Moderator: Wendy Weber, ND, PhD, MPH
*This session includes the Case Study Presentations.
Session 11: Assembling an ePCT Team & Writing a Grant Application
Beda Jean-Francois, PhD
Session 12: Next Steps
Wendy Weber, ND, PhD, MPH
Case Studies
Examples from NIH Collaboratory Trials:
- Advance Care Planning: Promoting Effective and Aligned Communication in the Elderly (ACP PEACE) (Angelo Volandes, MD, MPH)
- Nonpharmacologic Pain Management in Federally Qualified Health Centers Primary Care Clinics (BeatPain Utah) (Julie Fritz, PhD, PT)
- Guiding Good Choices for Health (GGC4H): Testing Feasibility and Effectiveness of Universal Parent-Focused Prevention in Three Healthcare Systems (Margaret Kuklinski, PhD)
- UH3 Project: Improving Chronic Disease Management with Pieces (ICD-Pieces™) (Miguel A. Vazquez, MD)