November 4-5, 2025: This 2-day workshop focused on the perspectives of providers, healthcare systems, regulators, and payers that can inform better approaches to research embedded in healthcare delivery. A series of panels discussed considerations for research in healthcare systems across a variety of communities; platform trials as an emerging method; implications of pragmatic trials with null findings for future pragmatic research; and the role of pragmatic trials in comparative effectiveness research of artificial intelligence algorithms.
Agenda, Slides, and Recordings
Day 1: November 4
Welcome and Introduction
Wendy Weber, ND, PhD, MPH*
Helene Langevin, MD*
Presented by: Lesley Curtis, PhD
Keynote: Landscape of Healthcare in America: Gaps and Opportunities (That Researchers Need to Hear)
David Zaas, MD, MBA
Session 1: Understanding Needs and Priorities of Health Systems Across Communities
Moderator: Cherise Harrington, PhD, MPH
Panel:
- Aimee Eden, PhD, MPH*
- Rachel Gold, PhD, MPH
- Caleb Holtzer, MD, MPH
- Ann Sheehy, MD, MS*
- Sebastian Tong, MD, MPH
Session 2: Realizing the Potential of Platform Trials
Moderator: Adrian Hernandez, MD, MHS
Panel:
- Marianne Kearney Chase
- Martin Landray, MB ChB, PhD
- Gregory Levin, PhD
- Christopher Lindsell, PhD
- Bijoy Menon, MBBS, MD, DM, MSc
Summary and Concluding Remarks
Lesley Curtis, PhD
Cherise Harrington, PhD, MPH
Adrian Hernandez, MD, MHS
Wendy Weber, ND, PhD, MPH*
Day 2: November 5
Welcome and Introduction
Wendy Weber, ND, PhD, MPH*
Helene Langevin, MD*
Presented by: Kevin Weinfurt, PhD
Session 3: What Do We Learn From Null Pragmatic Trials?
Presenter: Kevin Weinfurt, PhD
Moderator: Josephine Briggs, MD
Panel:
- Corita Grudzen, MD, MSHS
- Michael Ho, MD, PhD
- Vincent Mor, PhD
- Miguel Vazquez, MD
Session 4: What Is the Role of ePCTs in the Age of Artificial Intelligence?
Moderator: Emily O'Brien, PhD
Panel:
- Adrian Hernandez, MD, MHS
- Michael Ho, MD, PhD
- Rohan Khera, MD, MS
- Edward Melnick, MD, MHS
- Jeremy Sugarman, MD, MPH, MA
- Kenneth Wiley, PhD*
Summary and Concluding Remarks
Josephine Briggs, MD
Lesley Curtis, PhD
Emily O'Brien, PhD
Wendy Weber, ND, PhD, MPH*
Kevin Weinfurt, PhD
*Participated in workshop planning but unable to attend the live event due to the federal government shutdown.