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Living Textbook of
Pragmatic Clinical Trials

COVID-19 Resources

Access the latest information on COVID-19 for clinical researchers
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Rethinking Clinical Trials

A Living Textbook of Pragmatic Clinical Trials

  • Design
    • What is a Pragmatic Clinical Trial?
    • Decentralized Pragmatic Clinical Trials
    • Developing a Compelling Grant Application
    • Experimental Designs and Randomization Schemes
    • Endpoints and Outcomes
    • Analysis Plan
    • Using Electronic Health Record Data
    • Building Partnerships and Teams to Ensure a Successful Trial
    • Intervention Delivery and Complexity
    • Patient Engagement
  • Data, Tools & Conduct
    • Assessing Feasibility
    • Acquiring Real-World Data
    • Assessing Fitness-for-Use of Real-World Data
    • Study Startup
    • Participant Recruitment
    • Monitoring Intervention Fidelity and Adaptations
    • Patient-Reported Outcomes
    • Clinical Decision Support
    • Electronic Health Records–Based Phenotyping
    • Navigating the Unknown
  • Dissemination & Implementation
    • Data Sharing and Embedded Research
    • Dissemination Approaches for Different Audiences
    • Implementation
    • End-of-Trial Decision-Making
  • Ethics & Regulatory
    • Privacy Considerations
    • Identifying Those Engaged in Research
    • Collateral Findings
    • Consent, Disclosure, and Non-Disclosure
    • Data and Safety Monitoring
    • Ethical Considerations of Data Sharing in Pragmatic Clinical Trials
    • Ethics for AI and ML
    • IRB Responsibilities and Procedures
10 events found.

COVID-19

  1. Events
  2. COVID-19

Events

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  • August 2021

  • Fri 13

    Grand Rounds August 13: Got anything for this cough? Outpatient Treatment Trials in the Time of COVID

    August 13, 2021 @ 1:00 pm - 2:00 pm

    Speaker: Davey Smith, MD Protocol Co-Chair ACTIV-2 Professor of Medicine, UC San Diego Topic: Got anything for this cough? Outpatient Treatment Trials in the Time of COVID Date: Friday, August 13, 2021, 1:00-2:00 p.m. ET Meeting Info: To check whether you have the appropriate players installed for UCF (Universal Communications Format) rich media files, go […]

  • Fri 20

    Grand Rounds August 20: Fluvoxamine for Early Treatment of COVID-19: The STOP COVID Clinical Trials

    August 20, 2021 @ 1:00 pm - 2:00 pm

    Speaker: Eric Lenze, MD Wallace and Lucille K. Renard Professor of Psychiatry Washington University School of Medicine, St. Louis Topic: Fluvoxamine for Early Treatment of COVID-19: The STOP COVID Clinical Trials Date: Friday, August 20, 2021, 1:00-2:00 p.m. ET Meeting Info: To check whether you have the appropriate players installed for UCF (Universal Communications Format) […]

  • October 2021

  • Fri 1

    Grand Rounds October 1: COVID-OUT: From Computer Modeling to a Phase III Trial of Early Outpatient Treatment for SARS-CoV-2 Infection

    October 1, 2021 @ 1:00 pm - 2:00 pm

    Speakers: Carolyn Bramante, MD, MPH Division of General Internal Medicine Departments of Internal Medicine and Pediatrics Core faculty in the Program in Health Disparities Research and the Center for Pediatric […]

  • November 2021

  • Fri 12

    Grand Rounds November 12: Using Financial Incentives to Increase COVID-19 Vaccine Uptake

    November 12, 2021 @ 1:00 pm - 2:00 pm

    Speakers: Charlene Wong, MD MSHP Associate Professor of Pediatrics and Public Policy Duke University School of Medicine Chief Health Policy Officer for COVID-19 North Carolina Department of Health and Human […]

  • January 2022

  • Fri 14

    Grand Rounds January 14: Searching for a Unicorn: Understanding Stakeholder Perspectives When Selecting Outcomes for Outpatient Trials

    January 14, 2022 @ 1:00 pm - 2:00 pm

    Speaker: Christopher Lindsell, PhD Professor of Biostatistics and Biomedical Informatics Director, Vanderbilt Institute for Clinical and Translational Research (VICTR) Methods Program Codirector, Vanderbilt Health Data Science (HEADS) Center Topic: Searching […]

  • April 2022

  • Fri 8

    Grand Rounds April 8: COVID-19 Surveillance in PCORnet: Year 2 Update (Jason Block, MD, MPH; Thomas W. Carton, PhD, MS)

    April 8, 2022 @ 1:00 pm - 2:00 pm
    https://dukemed.webex.com/dukemed/j.php?MTID=m4c6e3e4827442a92338a5649cee613e6

    Speaker: Jason Block, MD, MPH Associate Professor Harvard Pilgrim Health Care Institute Harvard Medical School Thomas W. Carton, PhD, MS Chief Data Officer Louisiana Public Health Institute Topic: COVID-19 Surveillance in PCORnet: Year 2 Update Date: Friday, April 8, 2022, 1:00-2:00 pm ET Meeting Info: To check whether you have the appropriate players installed for […]

  • July 2022

  • Fri 8

    Grand Rounds July 8: Results From the COVID-OUT Trial, a Phase-3 Trial of Outpatient Treatment for COVID-19 Using Metformin, Ivermectin, and Fluvoxamine (Carolyn Bramante, MD, MPH; Thomas Murray, PhD; Jaren Huling, PhD)

    July 8, 2022 @ 1:00 pm - 2:00 pm

    Speakers: Carolyn Bramante, MD, MPH Assistant Professor, General Internal Medicine and Pediatrics Core Faculty, Center for Pediatric Obesity Medicine Core Faculty, Program for Health Disparities Research University of Minnesota Medical School Thomas Murray, PhD Assistant Professor of Biostatistics Division of Biostatistics University of Minnesota School of Public Health Jared Huling, PhD Assistant Professor of Biostatistics […]

  • Fri 15

    Grand Rounds July 15: Overview of Accelerating COVID-19 Therapeutic Interventions and Vaccines (ACTIV) Public-Private Partnership and Lessons Learned (Stacey J. Adam, PhD)

    July 15, 2022 @ 1:00 pm - 2:00 pm

    Speaker: Stacey J. Adam, PhD Associate Vice President, Research Partnerships Foundation for the NIH   Topic: Overview of Accelerating COVID-19 Therapeutic Interventions and Vaccines (ACTIV) Public-Private Partnership and Lessons Learned Date: Friday, July 15, 2022, 1:00-2:00 p.m. ET   Meeting Info: To check whether you have the appropriate players installed for UCF (Universal Communications Format) […]

  • Fri 22

    Grand Rounds July 22: ACTIV-6: One Year Later and Trial Results for Ivermectin-400 and Inhaled Fluticasone (Susanna Naggie, MD, MHS)

    July 22, 2022 @ 1:00 pm - 2:00 pm

    Speaker: Susanna Naggie, MD, MHS Professor of Medicine Vice Dean for Clinical Research Duke University School of Medicine Infectious Diseases Research Duke Clinical Research Institute   Topic: ACTIV-6: 1-year Later and Trial Results for Ivermectin-400 and Inhaled Fluticasone Date: Friday, July 22, 2022, 1:00-2:00 p.m. ET   Meeting Info: To check whether you have the […]

  • Fri 29

    Grand Rounds July 29: Effect of Early Treatment With Single-Dose Pegylated Interferon Lambda Among Patients With COVID-19: Results From the TOGETHER Trial (Edward Mills, PhD, FRCP; Jeffrey S. Glenn, MD, PhD)

    July 29, 2022 @ 1:00 pm - 2:00 pm

    Speakers: Edward Mills, PhD, FRCP Professor Department of Health Research Methods, Evidence & Impact McMaster University, Canada Jeffrey S. Glenn, MD, PhD Joseph D. Grant Professor and Professor of Microbiology and Immunology Stanford University Topic: Effect of Early Treatment With Single-Dose Pegylated Interferon Lambda Among Patients With COVID-19: Results From the TOGETHER Trial Date: Friday, […]

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