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Living Textbook of
Pragmatic Clinical Trials

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Access the latest information on COVID-19 for clinical researchers
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Rethinking Clinical Trials

A Living Textbook of Pragmatic Clinical Trials

  • Design
    • What is a Pragmatic Clinical Trial?
    • Decentralized Pragmatic Clinical Trials
    • Developing a Compelling Grant Application
    • Experimental Designs and Randomization Schemes
    • Endpoints and Outcomes
    • Analysis Plan
    • Using Electronic Health Record Data
    • Building Partnerships and Teams to Ensure a Successful Trial
    • Intervention Delivery and Complexity
    • Patient Engagement
  • Data, Tools & Conduct
    • Assessing Feasibility
    • Acquiring Real-World Data
    • Assessing Fitness-for-Use of Real-World Data
    • Study Startup
    • Participant Recruitment
    • Monitoring Intervention Fidelity and Adaptations
    • Patient-Reported Outcomes
    • Clinical Decision Support
    • Mobile Health
    • Electronic Health Records–Based Phenotyping
    • Navigating the Unknown
  • Dissemination & Implementation
    • Data Sharing and Embedded Research
    • Dissemination Approaches for Different Audiences
    • Implementation
    • End-of-Trial Decision-Making
  • Ethics & Regulatory
    • Privacy Considerations
    • Identifying Those Engaged in Research
    • Collateral Findings
    • Consent, Disclosure, and Non-Disclosure
    • Data and Safety Monitoring
    • Ethical Considerations of Data Sharing in Pragmatic Clinical Trials
    • Ethics for AI and ML
    • IRB Responsibilities and Procedures
10 events found.

Events

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Today
  • March 2017

  • Fri 10

    Implementing PROVEN

    March 10, 2017 @ 1:00 pm - 2:00 pm

    Presenter: Mor, Vincent Slides: Slides Video: Grand-Rounds-03-10-17

  • Fri 17

    Establishing the National Evaluation System for Health Technology (NEST) Coordinating Center

    March 17, 2017 @ 1:00 pm - 2:00 pm

    Presenter: Murray, Bill Slides: SlidesVideo: Grand-Rounds-03-17-17

  • Fri 24

    Patient-Reported Outcomes: A Critical Insight into the Impact of Therapy

    March 24, 2017 @ 1:00 pm - 2:00 pm

    Presenter: Spertus, John Slides: Slides Video: Grand-Rounds-03-24-17

  • Fri 31

    FDA and Pragmatic Trials

    March 31, 2017 @ 1:00 pm - 2:00 pm

    Presenter: Califf, Robert Slides: Slides Video: Grand-Rounds-03-31-17

  • April 2017

  • Fri 7

    Healthy Hearts Northwest: A 2×2 Randomized Factorial Trial to Build Quality Improvement Capacity in Primary Care

    April 7, 2017 @ 1:00 pm - 2:00 pm

    Presenter: Parchman, Michael Slides: Slides Video: Grand-Rounds-04-07-17

  • Thu 13

    Hardwiring Patient Engagement to Deliver Better Health

    April 13, 2017 @ 9:00 am - 1:00 pm
    https://dukemed.webex.com/dukemed/j.php?MTID=m4c6e3e4827442a92338a5649cee613e6

    Speakers: Multiple Speakers; Produced by NEJM Catalyst and hosted by Kaiser Permanente Southern California Topic: Hardwiring Patient Engagement to Deliver Better Health Date: Thursday, April 13, 2017, 9:00 a.m-1:00 p.m. ET Meeting Info: In this free, live web event from NEJM Catalyst, you’ll learn how to design provider care teams, patient networks, and patient-provider interactions […]

  • Fri 14

    Toward National Trauma Care Practice Change for PTSD & Comorbidity: Lessons Learned from the TSOS Pragmatic Trial

    April 14, 2017 @ 1:00 pm - 2:00 pm

    Presenter: Jurkovich, Gregory Slides: Slides Video: Grand-Rounds-04-14-17

  • Fri 21

    Testing New Models of Research Funding: One Brave Idea

    April 21, 2017 @ 1:00 pm - 2:00 pm

    Presenter: MacRae, Calum Slides: Slides Video: Grand-Rounds-04-21-17

  • Fri 28

    Perspective on the Boundary Between Quality Improvement Studies and Research: Patients, QI Leaders, IRB Leaders

    April 28, 2017 @ 1:00 pm - 2:00 pm

    Presenters: Sherrie Kaplan, Susan Huang Slides: Slides Video: Grand-Rounds-04-28-17

  • May 2017

  • Fri 5

    Grand Rounds: May 5: SUPPORT, BOOST II, and COT Trials: You Must Understand Usual Care to Safeguard Patients and Make Firm Conclusions (Charles Natanson, MD)

    May 5, 2017 @ 1:00 pm - 2:00 pm
    https://dukemed.webex.com/dukemed/j.php?MTID=m4c6e3e4827442a92338a5649cee613e6

    ​Speaker: Charles Natanson, MD Senior Investigator National Institutes of Health Slide: Slides Video: Grand-Rounds-5-5-17 Topic:SUPPORT, BOOST II, and COT Trials: You Must Understand Usual Care to Safeguard Patients and Make Firm Conclusions Date: Friday, May 5, 2017, 1:00-2:00 p.m. ET Meeting Info: To check whether you have the appropriate players installed for UCF (Universal Communications Format) rich […]

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