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Living Textbook of
Pragmatic Clinical Trials

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Access the latest information on COVID-19 for clinical researchers
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Rethinking Clinical Trials

A Living Textbook of Pragmatic Clinical Trials

  • Design
    • What is a Pragmatic Clinical Trial?
    • Decentralized Pragmatic Clinical Trials
    • Developing a Compelling Grant Application
    • Experimental Designs and Randomization Schemes
    • Endpoints and Outcomes
    • Analysis Plan
    • Using Electronic Health Record Data
    • Building Partnerships and Teams to Ensure a Successful Trial
    • Intervention Delivery and Complexity
    • Patient Engagement
  • Data, Tools & Conduct
    • Assessing Feasibility
    • Acquiring Real-World Data
    • Assessing Fitness-for-Use of Real-World Data
    • Study Startup
    • Participant Recruitment
    • Monitoring Intervention Fidelity and Adaptations
    • Patient-Reported Outcomes
    • Clinical Decision Support
    • Mobile Health
    • Electronic Health Records–Based Phenotyping
    • Navigating the Unknown
  • Dissemination & Implementation
    • Data Sharing and Embedded Research
    • Dissemination Approaches for Different Audiences
    • Implementation
    • End-of-Trial Decision-Making
  • Ethics & Regulatory
    • Privacy Considerations
    • Identifying Those Engaged in Research
    • Collateral Findings
    • Consent, Disclosure, and Non-Disclosure
    • Data and Safety Monitoring
    • Ethical Considerations of Data Sharing in Pragmatic Clinical Trials
    • Ethics for AI and ML
    • IRB Responsibilities and Procedures
10 events found.

Events

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  • August 2024

  • Fri 23

    Grand Rounds August 23, 2024: Improving Quality of Life in COPD and Heart Failure: Unpacking a Successful Multicomponent Virtual Team Intervention (David B. Bekelman, MD, MPH; Lyndsay DeGroot PhD, RN, CNE)

    August 23, 2024 @ 1:00 pm - 2:00 pm

    Speakers: David B. Bekelman, MD, MPH Professor of Medicine and Psychiatry Rocky Mountain Regional VAMC and University of Colorado Division of General Internal Medicine Lyndsay DeGroot PhD, RN, CNE Postdoctoral Fellow University of Colorado Anschutz Medical Campus School of Medicine Title: Improving Quality of Life in COPD and Heart Failure: Unpacking a Successful Multicomponent Virtual […]

  • September 2024

  • Fri 6

    Grand Rounds September 6, 2024: Conventional, Complementary, and Integrative Pain Therapies in a Military Population With Chronic Musculoskeletal Pain: Results of a Pragmatic Clinical Trial Using SMART Design (Ardith Z. Doorenbos, PhD, RN; Diane M. Flynn, MD, MPH)

    September 6, 2024 @ 1:00 pm - 2:00 pm

    Speakers: Ardith Z. Doorenbos, PhD, RN Professor Department of Biobehavioral Nursing Science College of Nursing University of Illinois, Chicago Diane M. Flynn, MD, MPH Primary Care Pain Management Advisor Interdisciplinary Pain Management Center Madigan Army Medical Center Tacoma, WA Title: Conventional, Complementary, and Integrative Pain Therapies in a Military Population With Chronic Musculoskeletal Pain: Results […]

  • Tue 10

    Scalable Mindfulness-Based Interventions for Chronic Pain: Results from the Learning to Apply Mindfulness to Pain (LAMP) Trial

    September 10, 2024 @ 11:00 am - 12:00 pm

    Diana Burgess, PhD Register for the webinar   Agenda Dr. Burgess will present results of the Learning to Apply Mindfulness to Pain (LAMP) multisite, pragmatic clinical trial, which compares two scalable, mindfulness-based interventions (MBIs) for Veterans with chronic pain. Both LAMP interventions improved pain functioning (the primary outcome) and important biopsychosocial outcomes (e.g., pain intensity; […]

  • Fri 13

    Grand Rounds September 13, 2024: The HARMONIE Trial: Reimagining How to Design and Deliver Contract Commercial Clinical Trials (Saul N. Faust, PhD)

    September 13, 2024 @ 1:00 pm - 2:00 pm

    Speaker: Saul N. Faust, PhD Professor University of Southampton Southampton, UK Title: The HARMONIE Trial: Re-imagining How to Design and Deliver Contract Commercial Clinical Trials Date: Friday, September 13, 2024, 1:00-2:00 p.m. ET Please click the link below to join the webinar: https://duke.zoom.us/j/93706744059?pwd=RazMPKCr4ha3VHMv1IVjylmjDln0vb.1 Passcode: 803617 One tap mobile +13126266799,,93706744059#,,,,*803617# US (Chicago) +16468769923,,93706744059#,,,,*803617# US (New York) […]

  • Thu 19

    IMPACT Grand Rounds: Evidence for Reducing Infections, Hospitalizations, and Antibiotic Resistant Pathogens in Nursing Homes Through Universal Nasal Decolonization and Bathing with Chlorhexidine

    September 19, 2024 @ 12:00 pm - 1:00 pm

    IMPACT Grand Rounds Susan Huang, MD, MPH "Evidence for Reducing Infections, Hospitalizations, and Antibiotic Resistant Pathogens in Nursing Homes Through Universal Nasal Decolonization and Bathing with Chlorhexidine" Susan Huang, MD, MPH, is a professor in the Division of Infectious Diseases and Health Policy Research Institute at the University of California Irvine School of Medicine, and […]

  • Fri 20

    Grand Rounds September 20, 2024: Similarities and Differences Between Pragmatic Trials and Hybrid Effectiveness-Implementation Trials (John Fortney, PhD)

    September 20, 2024 @ 1:00 pm - 2:00 pm

    Speaker: John Fortney, PhD Professor Department of Psychiatry and Behavioral Sciences University of Washington Senior Research Career Scientist HSR Center of Innovation for Veteran-Centered and Value-Driven Care VA Puget Sound Health Care System Title: Similarities and Differences Between Pragmatic Trials and Hybrid Effectiveness-Implementation Trials Date: Friday, September 20, 2024, 1:00-2:00 p.m. ET Please click the […]

  • Fri 27

    Implications of Informative Cluster Size for the Design and Analysis of Cluster Randomized Trials

    September 27, 2024 @ 11:00 am - 12:00 pm

    Methods: Mind the Gap Webinar Series Implications of Informative Cluster Size for the Design and Analysis of Cluster Randomized Trials Presented by Brennan Kahan, PhD September 27, 2024 11:00 am-12:00 noon ET Register now About the Webinar Cluster randomized trials involve randomizing groups of participants, such as schools, hospitals, or villages, between different interventions. Because […]

  • Fri 27

    Grand Rounds September 27, 2024: Azithromycin for Childhood Mortality: Randomizing Entire Countries (Tom Lietman, MD)

    September 27, 2024 @ 1:00 pm - 2:00 pm

    Speaker: Tom Lietman, MD Director Francis I. Proctor Foundation University of California, San Francisco Title: Azithromycin for Childhood Mortality: Randomizing Entire Countries Date: Friday, September 27, 2024, 1:00-2:00 p.m. ET Please click the link below to join the webinar: https://duke.zoom.us/j/93281345354?pwd=k60xHNNqlBhr8uD2D6ICW8bHn1dKf7.1 Passcode: 614354 One tap mobile +16468769923,,93281345354#,,,,*614354# US (New York) +16469313860,,93281345354#,,,,*614354# US Audio Only Options +1 […]

  • October 2024

  • Tue 1

    Implementation of New Physical Therapy Programs for Knee Osteoarthritis in the VA

    October 1, 2024 @ 11:00 am - 12:00 pm

    Kelli Allen, PhD Register for the webinar   About the Spotlight on Pain Management Cyberseminar Series The Pain Management Collaboratory (PMC) is delighted to share plans for sponsoring a special series of presentations as part of the VA Spotlight on Pain Management (SoPM) Cyberseminar series that will highlight the accomplishments and future initiatives of the […]

  • Fri 4

    Grand Rounds October 4, 2024: Health Trends Across Communities – A Novel Health System-Public Health Data Partnership (Tyler Winkelman, MD, MSc; David Johnson, MPH)

    October 4, 2024 @ 1:00 pm

    Speakers: Tyler Winkelman, MD, MSc Division Director, General Internal Medicine Hennepin Healthcare Co-Director, Health, Homelessness, and Criminal Justice Lab HHRI David Johnson, MPH Health Informatics and Epidemiology Program Manager Hennepin County Title: Health Trends Across Communities – A Novel Health System-Public Health Data Partnership Date: Friday, October 4, 2024, 1:00-2:00 p.m. ET Please click the […]

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