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Living Textbook of
Pragmatic Clinical Trials

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Access the latest information on COVID-19 for clinical researchers
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Rethinking Clinical Trials

A Living Textbook of Pragmatic Clinical Trials

  • Design
    • What is a Pragmatic Clinical Trial?
    • Decentralized Pragmatic Clinical Trials
    • Developing a Compelling Grant Application
    • Experimental Designs and Randomization Schemes
    • Endpoints and Outcomes
    • Analysis Plan
    • Using Electronic Health Record Data
    • Building Partnerships and Teams to Ensure a Successful Trial
    • Intervention Delivery and Complexity
    • Patient Engagement
  • Data, Tools & Conduct
    • Assessing Feasibility
    • Acquiring Real-World Data
    • Assessing Fitness-for-Use of Real-World Data
    • Study Startup
    • Participant Recruitment
    • Monitoring Intervention Fidelity and Adaptations
    • Patient-Reported Outcomes
    • Clinical Decision Support
    • Mobile Health
    • Electronic Health Records–Based Phenotyping
    • Navigating the Unknown
  • Dissemination & Implementation
    • Data Sharing and Embedded Research
    • Dissemination Approaches for Different Audiences
    • Implementation
    • End-of-Trial Decision-Making
  • Ethics & Regulatory
    • Privacy Considerations
    • Identifying Those Engaged in Research
    • Collateral Findings
    • Consent, Disclosure, and Non-Disclosure
    • Data and Safety Monitoring
    • Ethical Considerations of Data Sharing in Pragmatic Clinical Trials
    • Ethics for AI and ML
    • IRB Responsibilities and Procedures
10 events found.

Events

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  • October 2024

  • Fri 11

    Grand Rounds October 11, 2024: Early Diagnosis and Treatment of Asthma and COPD (Shawn Aaron, MD)

    October 11, 2024 @ 1:00 pm - 2:00 pm

    Speaker: Shawn Aaron, MD Professor University of Ottawa Title: Early Diagnosis and Treatment of Asthma and COPD Date: Friday, October 11, 2024, 1:00-2:00 p.m. ET Please click the link below to join the webinar: https://duke.zoom.us/j/98571026630?pwd=COEg4a7tagfZe59V0yFjgK88fdMZiV.1 Passcode: 654855 One tap mobile +16468769923,,98571026630#,,,,*654855# US +16469313860,,98571026630#,,,,*654855# US Audio Only Options +1 646 876 9923 US International numbers available: […]

  • Fri 18

    Grand Rounds October 18, 2024: Rigorous Testing of Behavior Change Interventions: Lessons from the BE ACTIVE Randomized Clinical Trial (Alexander Fanaroff, MD, MHS)

    October 18, 2024 @ 1:00 pm - 2:00 pm

    Speaker: Alexander Fanaroff, MD, MHS Assistant Professor of Medicine Perelman School of Medicine University of Pennsylvania Title: Rigorous Testing of Behavior Change Interventions: Lessons from the BE ACTIVE Randomized Clinical Trial Date: Friday, October 18, 2024, 1:00-2:00 p.m. ET Please click the link below to join the webinar: https://duke.zoom.us/j/97159816180?pwd=89hAcOZ4rhwLMCPhX0ILdxzaimlyMp.1 Passcode: 796831 One tap mobile +13092053325,,97159816180#,,,,*796831# […]

  • Fri 18

    Evaluating Synergies in Multilevel Interventions: Mental Health in Schools as an Exemplar

    October 18, 2024 @ 2:00 pm - 3:00 pm

    Evaluating Synergies in Multilevel Interventions: Mental Health in Schools as an Exemplar Marta I. Mulawa, Ph.D., M.H.S. About the Webinar Multilevel interventions are essential for addressing complex societal challenges, such as systemic racism in educational institutions, but they present unique evaluation challenges. These interventions inherently operate across multiple levels of influence, such as schools and […]

  • Fri 25

    Grand Rounds October 25, 2024: Hybrid Working from Home Improves Retention Without Damaging Performance (Nicholas Bloom, PhD)

    October 25, 2024 @ 1:00 pm - 2:00 pm

    Speaker: Nicholas Bloom, PhD Professor of Economics Stanford University Title: Hybrid Working from Home Improves Retention Without Damaging Performance Date: Friday, October 25, 2024, 1:00-2:00 p.m. ET Please click the link below to join the webinar: https://duke.zoom.us/j/98530027832?pwd=wEji7XrWFOYf8cX0vO8rIYNNEo5k9b.1 Passcode: 332907 One tap mobile +16468769923,,98530027832#,,,,*332907# US +16469313860,,98530027832#,,,,*332907# US Audio Only Options +1 646 876 9923 US (New […]

  • Tue 29

    Using LTC Data Cooperative – CMS Linked Data

    October 29, 2024 @ 1:00 pm - 2:00 pm

    A special workshop cohosted by the NIA IMPACT Collaboratory and the NIH Data LINKAGE Program Join the interactive session to: Discover how to leverage the LTC Data Cooperative for your research Understand the application process Explore the types of studies suitable for these datasets Get your questions answered! Register at https://acumenllc.zoom.us/webinar/register/WN_nHgVDePjREWxhwbObhDY4A#/registration This session will be […]

  • November 2024

  • Fri 1

    Grand Rounds November 1, 2024: Congenital Heart Initiative: Redefining Outcomes and Navigation to Adult Centered Care (CHI-RON) Study (Thomas W. Carton, PhD, MS; Anitha S. John, MD, PhD)

    November 1, 2024 @ 1:00 pm - 2:00 pm

    Speakers: Thomas W. Carton, PhD, MS Chief Data and Strategy Officer Louisiana Public Health Institute Anitha S. John, MD, PhD Medical Director Washington Adult Congenital Heart Program Professor of Pediatrics Children’s National Hospital George Washington University Title: Congenital Heart Initiative: Redefining Outcomes and Navigation to Adult Centered Care (CHI-RON) Study Date: Friday, November 1, 2024, […]

  • Tue 5

    Optimizing Equity and Inclusion in Pragmatic Clinical Trials: Findings from the Pain Management Collaboratory

    November 5, 2024 @ 11:00 am - 12:00 pm

    Travis Lovejoy, PhD Register for the webinar   About the Spotlight on Pain Management Cyberseminar Series The Pain Management Collaboratory (PMC) is delighted to share plans for sponsoring a special series of presentations as part of the VA Spotlight on Pain Management (SoPM) Cyberseminar series that will highlight the accomplishments and future initiatives of the […]

  • Fri 8

    Grand Rounds November 8, 2024: The Effect of Cash Benefits on Health Care Utilization and Health: A Randomized Study of an Income Support (Sumit Agarwal, MD, MPH, PhD)

    November 8, 2024 @ 1:00 pm - 2:00 pm

    Speaker: Sumit Agarwal, MD, MPH, PhD Assistant Professor Division of General Medicine University of Michigan Title: The Effect of Cash Benefits on Health Care Utilization and Health: A Randomized Study of an Income Support Date: Friday, November 8, 2024, 1:00-2:00 p.m. ET Please click the link below to join the webinar: https://duke.zoom.us/j/97908550114?pwd=cEQNu6DAzkJT39AAZa1hHT95lI5Bvb.1 Passcode: 843573 One-Tap Mobile […]

  • Fri 15

    Grand Rounds November 15, 2024: Pragmatic Randomized Trial of Smartphone-Based Nudges to Reduce Distracted Driving Among US Auto Insurance Customers (M. Kit Delgado, MD, MS)

    November 15, 2024 @ 1:00 pm - 2:00 pm

    Speaker: M. Kit Delgado, MD, MS Associate Professor of Emergency Medicine and Epidemiology Faculty Director, Penn Medicine Nudge Unit Title: Pragmatic Randomized Trial of Smartphone-Based Nudges to Reduce Distracted Driving Among US Auto Insurance Customers Date: Friday, November 15, 2024, 1:00-2:00 p.m. ET Please click the link below to join the webinar: https://duke.zoom.us/j/97510856611?pwd=QAw15vhBbv7ybmEd5akvaA7VCWrVA5.1 Passcode: 858104 […]

  • Fri 22

    Grand Rounds November 22, 2024: Tranexamic Acid in Patients Undergoing Liver Resection: The HeLiX Randomized Clinical Trial (Paul J. Karanicolas, MD, PhD, FRCSC)

    November 22, 2024 @ 1:00 pm - 2:00 pm

    Speaker: Paul J. Karanicolas, MD, PhD, FRCSC Sherif and Mary-Lou Hanna Chair, Surgical Oncology Research The Edmond Odette Cancer Centre @ Sunnybrook Health Sciences Centre Professor of Surgery University of Toronto Title: Tranexamic Acid in Patients Undergoing Liver Resection: The HeLiX Randomized Clinical Trial Date: Friday, November 22, 2024, 1:00-2:00 p.m. ET Please click the […]

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