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Living Textbook of
Pragmatic Clinical Trials

COVID-19 Resources

Access the latest information on COVID-19 for clinical researchers
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Rethinking Clinical Trials

A Living Textbook of Pragmatic Clinical Trials

  • Design
    • What is a Pragmatic Clinical Trial?
    • Decentralized Pragmatic Clinical Trials
    • Developing a Compelling Grant Application
    • Experimental Designs and Randomization Schemes
    • Endpoints and Outcomes
    • Analysis Plan
    • Using Electronic Health Record Data
    • Building Partnerships and Teams to Ensure a Successful Trial
    • Intervention Delivery and Complexity
    • Patient Engagement
  • Data, Tools & Conduct
    • Assessing Feasibility
    • Acquiring Real-World Data
    • Assessing Fitness-for-Use of Real-World Data
    • Study Startup
    • Participant Recruitment
    • Monitoring Intervention Fidelity and Adaptations
    • Patient-Reported Outcomes
    • Clinical Decision Support
    • Mobile Health
    • Electronic Health Records–Based Phenotyping
    • Navigating the Unknown
  • Dissemination & Implementation
    • Data Sharing and Embedded Research
    • Dissemination Approaches for Different Audiences
    • Implementation
    • End-of-Trial Decision-Making
  • Ethics & Regulatory
    • Privacy Considerations
    • Identifying Those Engaged in Research
    • Collateral Findings
    • Consent, Disclosure, and Non-Disclosure
    • Data and Safety Monitoring
    • Ethical Considerations of Data Sharing in Pragmatic Clinical Trials
    • Ethics for AI and ML
    • IRB Responsibilities and Procedures
10 events found.

Events

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  • December 2024

  • Tue 3

    How Many Chiropractic Visits Does it Take to Help Veterans with Chronic Low Back Pain? Part 1: Characteristics of the VERDICT Sample

    December 3, 2024 @ 11:00 am - 12:00 pm

    Cynthia Long, PhD, PStat & Christine Goertz, DC, PhD Register for the webinar   About the Spotlight on Pain Management Cyberseminar Series The Pain Management Collaboratory (PMC) is delighted to share plans for sponsoring a special series of presentations as part of the VA Spotlight on Pain Management (SoPM) Cyberseminar series that will highlight the […]

  • Fri 6

    Grand Rounds December 6, 2024: Opportunities and Challenges in the Use of Large Language Models for Post-Marketing Surveillance of Medical Products (Michael E. Matheny, MD, MS, MPH)

    December 6, 2024 @ 1:00 pm - 2:00 pm

    Speaker: Michael E. Matheny, MD, MS, MPH Director, Center for Improving the Public’s Health Through Informatics Professor of Biomedical Informatics, Biostatistics, and Medicine Vanderbilt University Medical Center Staff Scientist, Geriatrics Research Education and Clinical Care Service Associate Director, VA ORD VINCI Tennessee Valley Healthcare System VA Title: Opportunities and Challenges in the Use of Large […]

  • Fri 13

    Grand Rounds December 13, 2024: Home Blood Pressure Telemonitoring and Nurse Case Management in Black and Hispanic Patients With Stroke: A Randomized Clinical Trial (Gbenga Ogedegbe, MD, MPH)

    December 13, 2024 @ 1:00 pm - 2:00 pm

    Speaker: Gbenga Ogedegbe, MD, MPH Dr. Adolph & Margaret Berger Professor of Population Health NYU Grossman School of Medicine Director, Institute for Excellence in Health Equity (IEHE) NYU Langone Health […]

  • Fri 20

    Grand Rounds December 20, 2024: No Presentation (Holiday)

    December 20, 2024 @ 1:00 pm - 2:00 pm
  • Fri 27

    Grand Rounds December 27, 2024: No Presentation (Holiday)

    December 27, 2024 @ 1:00 pm - 2:00 pm
  • January 2025

  • Fri 3

    Grand Rounds January 3, 2025: No Presentation (Holiday)

    January 3, 2025 @ 1:00 pm - 2:00 pm
  • Fri 10

    Grand Rounds January 10, 2025: FM-TIPS Community Engagement Methods for Recruitment (Heather Schacht Reisinger, PhD; Dana Dailey PT, PhD)

    January 10, 2025 @ 1:00 pm - 2:00 pm

    Speakers: Heather Schacht Reisinger, PhD Director, Implementation Science Center Associate Director for Engagement, Integration, and Implementation Institute for Clinical and Translational Science Professor, Division of General Internal Medicine at the University of Iowa Dana Dailey PT, PhD Assistant Research Scientist Physical Therapy and Rehabilitation Science University of Iowa Associate Professor, Physical Therapy Department St. Ambrose […]

  • Fri 17

    Grand Rounds January 17, 2025: Design for Diversity (Christopher J. Lindsell, PhD)

    January 17, 2025 @ 1:00 pm - 2:00 pm

    Speaker: Christopher J Lindsell, PhD Professor and co-Chief, Biostatistics, Duke University Director, Data Science and Biostatistics, DCRI Director, Biostatistics and Bioinformatics, CTSI Editor in Chief, Journal of Clinical and Translational Science Title: Design for Diversity Date: Friday, January 17, 2025, 1:00-2:00 p.m. ET Please click the link below to join the webinar: https://duke.zoom.us/j/93335850517?pwd=btse5EdkYAQa9Z2T7LP4OSbJz4oKne.1 Passcode: 429891 […]

  • Fri 24

    Grand Rounds January 24, 2025: The HEALing Communities Study – 10 Million People, 67 Communities: A Community-Based Cluster Randomized Trial to Reduce Opioid Overdose Deaths (Jeffrey H. Samet, MD, MA, MPH)

    January 24, 2025 @ 1:00 pm - 2:00 pm

    Speaker: Jeffrey H. Samet, MD, MA, MPH John Noble Professor in General Internal Medicine & Professor of Public Health Boston University Chobanian and Avedisian School of Medicine and School of Public Health Boston Medical Center Title: The HEALing Communities Study – 10 Million People, 67 Communities: A Community-based Cluster Randomized Trial to Reduce Opioid Overdose […]

  • Fri 31

    Grand Rounds January 31, 2025: Advancing Rural Back Pain Outcomes Using Rehabilitation Telehealth (ARBOR-Telehealth): Early Progress and Lessons Learned (Richard L. Skolasky, ScD; Kevin H. McLaughlin, DPT)

    January 31, 2025 @ 1:00 pm - 2:00 pm

    Speakers: Richard L. Skolasky, ScD Professor, Johns Hopkins School of Medicine Department of Orthopaedic Surgery Kevin H. McLaughlin, DPT Assistant Professor, Johns Hopkins School of Medicine Department of Physical Medicine and Rehabilitation Title: Advancing Rural Back Pain Outcomes Using Rehabilitation Telehealth (ARBOR-Telehealth): Early Progress and Lessons Learned Date: Friday, January 31, 2025, 1:00-2:00 p.m. ET […]

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