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Living Textbook of
Pragmatic Clinical Trials

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Rethinking Clinical Trials

A Living Textbook of Pragmatic Clinical Trials

  • Design
    • What is a Pragmatic Clinical Trial?
    • Decentralized Pragmatic Clinical Trials
    • Developing a Compelling Grant Application
    • Experimental Designs and Randomization Schemes
    • Endpoints and Outcomes
    • Analysis Plan
    • Using Electronic Health Record Data
    • Building Partnerships and Teams to Ensure a Successful Trial
    • Intervention Delivery and Complexity
    • Patient Engagement
  • Data, Tools & Conduct
    • Assessing Feasibility
    • Acquiring Real-World Data
    • Assessing Fitness-for-Use of Real-World Data
    • Study Startup
    • Participant Recruitment
    • Monitoring Intervention Fidelity and Adaptations
    • Patient-Reported Outcomes
    • Clinical Decision Support
    • Mobile Health
    • Electronic Health Records–Based Phenotyping
    • Navigating the Unknown
  • Dissemination & Implementation
    • Data Sharing and Embedded Research
    • Dissemination Approaches for Different Audiences
    • Implementation
    • End-of-Trial Decision-Making
  • Ethics & Regulatory
    • Privacy Considerations
    • Identifying Those Engaged in Research
    • Collateral Findings
    • Consent, Disclosure, and Non-Disclosure
    • Data and Safety Monitoring
    • Ethical Considerations of Data Sharing in Pragmatic Clinical Trials
    • Ethics for AI and ML
    • IRB Responsibilities and Procedures
10 events found.

Events

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  • September 2017

  • Fri 8

    Grand Rounds September 8: Leveraging Informatics in Pragmatic Research: Initial Experience in PCORnet (Russell Rothman, MD, MPP)

    Featured September 8, 2017 @ 1:00 pm - 2:00 pm
    https://dukemed.webex.com/dukemed/j.php?MTID=m4c6e3e4827442a92338a5649cee613e6

    Speaker: Russell Rothman, MD, MPP Professor, Internal Medicine, Pediatrics, & Health Policy Vice President for Population Health Research Director, Center for Health Services Research Vanderbilt University Medical Center Topic: Leveraging Informatics in Pragmatic Research: Initial Experience in PCORnet Date: Friday, September 8, 2017, 1:00-2:00 p.m. ET Meeting Info: To check whether you have the appropriate […]

  • Fri 15

    Grand Rounds September 15, 2017: Who to Include in a Pragmatic Trial? It Depends (Greg Simon, MD; Laura Dember, MD)

    Featured September 15, 2017 @ 1:00 pm - 2:00 pm
    https://dukemed.webex.com/dukemed/j.php?MTID=m4c6e3e4827442a92338a5649cee613e6

    Speakers: Greg Simon, MD, MPH Senior Investigator Kaiser Permanente Washington Health Research Institute Laura Dember, MD Professor of Medicine University of Pennsylvania Perelman School of Medicine Topic: Who to Include […]

  • Fri 22

    Grand Rounds September 22: Improving Evidence Generation for Medical Devices: The New National Evaluation System for Health Technology (NEST) (Rachael Fleurence, PhD)

    Featured September 22, 2017 @ 1:00 pm - 2:00 pm
    https://dukemed.webex.com/dukemed/j.php?MTID=m4c6e3e4827442a92338a5649cee613e6

    Speaker: Rachael Fleurence, PhD Executive Director NEST Coordinating Center Medical Device Innovation Consortium (MDIC) Topic: Improving Evidence Generation for Medical Devices: The New National Evaluation System for Health Technology (NEST) […]

  • Fri 29

    Grand Rounds September 29: Preprints: What, Why Not and How (Harlan M. Krumholz, MD)

    Featured September 29, 2017 @ 1:00 pm - 2:00 pm
    https://dukemed.webex.com/dukemed/j.php?MTID=m4c6e3e4827442a92338a5649cee613e6

    Speakers: Harlan M. Krumholz, MD Harold H. Hines, Jr. Professor of Medicine Yale University School of Medicine Director, Center for Outcomes Research and Evaluation Yale-New Haven Health System Founder, Hugo […]

  • October 2017

  • Fri 6

    Grand Rounds October 6: Health Is More Than Healthcare (Karen B. DeSalvo, MD, MPH, MSc)

    Featured October 6, 2017 @ 1:00 pm - 2:00 pm
    https://dukemed.webex.com/dukemed/j.php?MTID=m4c6e3e4827442a92338a5649cee613e6

    Speaker: Karen DeSalvo, MD, MPH, MSc Former US HSS Acting Assistant Secretary for Health, National Coordinator for Health Information Technology Topic: Health Is More Than Healthcare Date: Friday, October 6, […]

  • Fri 6

    Grand Rounds October 6: Health is More than Healthcare (Karen DeSalvo, PhD)

    October 6, 2017 @ 1:00 pm - 2:00 pm

    Speakers: Karen DeSalvo, PhD Topic: Health is More than Healthcare Date: Friday, October 6, 2017, 1:00-2:00 p.m. ET Meeting Info: To check whether you have the appropriate players installed for […]

  • Fri 13

    Grand Rounds October 13: Users’ Guide for Integrating Patient-Reported Outcomes in Electronic Health Records (Claire Snyder, PhD; Albert Wu, MD, MPH)

    Featured October 13, 2017 @ 1:00 pm - 2:00 pm
    https://dukemed.webex.com/dukemed/j.php?MTID=m4c6e3e4827442a92338a5649cee613e6

    Speakers: Claire Snyder, PhD Professor of Medicine, Oncology, and Health Policy & Management Johns Hopkins Schools of Medicine and Public Health Albert W. Wu, MD, MPH, FACP Professor and Director […]

  • Fri 20

    Grand Rounds October 20: Automated Public Health Surveillance Using Electronic Health Record Data (Michael Klompas MD, MPH, FIDSA, FSHEA)

    Featured October 20, 2017 @ 1:00 pm - 2:00 pm
    https://dukemed.webex.com/dukemed/j.php?MTID=m4c6e3e4827442a92338a5649cee613e6

    Speaker: Michael Klompas, MD, MPH, FIDSA, FSHEA Associate Professor Department of Population Medicine Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, MA Topic: Automated Public Health Surveillance Using Electronic […]

  • November 2017

  • Fri 10

    Grand Rounds November 10: No Presentation (Veterans Day Holiday Weekend)

    November 10, 2017
    https://dukemed.webex.com/dukemed/j.php?MTID=m4c6e3e4827442a92338a5649cee613e6

    There will be no Grand Rounds presentation November 10, 2017 in observance of Veterans Day.  We hope to see you next week for "ICD-Pieces:  From Planning to Performance" by Miguel […]

  • Fri 17

    Grand Rounds November 17: ICD-Pieces: From Planning to Performance (Miguel A. Vazquez, MD; George Oliver, MD)

    Featured November 17, 2017 @ 1:00 pm - 2:00 pm
    https://dukemed.webex.com/dukemed/j.php?MTID=m4c6e3e4827442a92338a5649cee613e6

    Speakers: Miguel A. Vazquez, MD Professor of Medicine Clinical Chief Nephrology Division UT Southwestern Medical Center George Oliver, MD Vice President Clinical Informatics Parkland Center for Clinical Innovation Topic: ICD-Pieces:  […]

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