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Living Textbook of
Pragmatic Clinical Trials

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Rethinking Clinical Trials

A Living Textbook of Pragmatic Clinical Trials

  • Design
    • What is a Pragmatic Clinical Trial?
    • Decentralized Pragmatic Clinical Trials
    • Developing a Compelling Grant Application
    • Experimental Designs and Randomization Schemes
    • Endpoints and Outcomes
    • Analysis Plan
    • Using Electronic Health Record Data
    • Building Partnerships and Teams to Ensure a Successful Trial
    • Intervention Delivery and Complexity
    • Patient Engagement
  • Data, Tools & Conduct
    • Assessing Feasibility
    • Acquiring Real-World Data
    • Assessing Fitness-for-Use of Real-World Data
    • Study Startup
    • Participant Recruitment
    • Monitoring Intervention Fidelity and Adaptations
    • Patient-Reported Outcomes
    • Clinical Decision Support
    • Mobile Health
    • Electronic Health Records–Based Phenotyping
    • Navigating the Unknown
  • Dissemination & Implementation
    • Data Sharing and Embedded Research
    • Dissemination Approaches for Different Audiences
    • Implementation
    • End-of-Trial Decision-Making
  • Ethics & Regulatory
    • Privacy Considerations
    • Identifying Those Engaged in Research
    • Collateral Findings
    • Consent, Disclosure, and Non-Disclosure
    • Data and Safety Monitoring
    • Ethical Considerations of Data Sharing in Pragmatic Clinical Trials
    • Ethics for AI and ML
    • IRB Responsibilities and Procedures
10 events found.

Events

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  • November 2019

  • Fri 15

    Grand Rounds November 15: PCORnet: Health Plan Research Network Data Linkage and Patient Engagement with Patient-Powered Research Networks

    November 15, 2019 @ 1:00 pm - 2:00 pm

    Speaker: Kevin Haynes, PharmD, MSCE Principal Scientist HealthCore Topic: PCORnet: Health Plan Research Network Data Linkage and Patient Engagement with Patient-Powered Research Networks Date: Friday, November 15, 2019, 1:00-2:00 p.m. […]

  • Thu 21

    IMPACT Collaboratory: Are You Ready for a Pragmatic Trial? The RAPT Model and Implementation Considerations

    November 21, 2019 @ 12:00 pm - 1:00 pm

    Speakers: Rosa Baier, MPH Associate Director, Center for Long-Term Care Quality & Innovation Associate Professor, Health Sciences, Policy & Practice Brown University School of Medicine Eric Jutkowitz, PhD Assistant Professor […]

  • Fri 22

    Grand Rounds November 22: It’s Time to Learn From Patients Like Mine

    November 22, 2019 @ 1:00 pm - 2:00 pm

    Speaker: Nigam H Shah, MBBS, PhD Associate Professor of Medicine Stanford University Topic: It's Time to Learn From Patients Like Mine Date: Friday, November 22, 2019, 1:00-2:00 p.m. ET Meeting […]

  • Fri 29

    Grand Rounds November 29: No Presentation (Thanksgiving Holiday)

    November 29, 2019 @ 1:00 pm - 2:00 pm
  • December 2019

  • Fri 6

    Grand Rounds December 6: Millions More People, Stronger Collaborations: The New and Improved NIH Collaboratory Distributed Research Network

    December 6, 2019 @ 1:00 pm - 2:00 pm

    Speakers: Richard Platt, MD, MS Professor and Chair Harvard Medical School Department of Population Medicine Kevin Haynes, PharmD, MSCE Principal Scientist HealthCore Denise Boudreau, PhD Senior Scientific Investigator Kaiser Permanente […]

  • Fri 13

    Grand Rounds December 13: EMBED Update: Challenges and Solutions

    December 13, 2019 @ 1:00 pm - 2:00 pm

    Speakers: Edward R. Melnick, MD, MHS Assistant Professor of Emergency Medicine Program Director, Yale-VA Clinical Informatics Fellowship Program Principal Investigator, EMBED Trial Gail D’Onofrio, MD Professor & Chair Department of […]

  • Thu 19

    IMPACT Collaboratory Grand Rounds December 19: Stepped wedge cluster trials: what, how, and when?

    December 19, 2019 @ 12:00 pm - 1:00 pm

    Speakers:  Monica Taljaard, PhD Senior Scientist, Ottawa Hospital Research Institute Associate Professor, University of Ottawa Topic:  Stepped wedge cluster trials: what, how, and when? Date: Thursday, December 19, 2019, 12:00-1:00 […]

  • Fri 20

    Grand Rounds December 20: No Presentation (Holiday Break)

    December 20, 2019 @ 1:00 pm - 2:00 pm
  • Fri 27

    Grand Rounds December 27: No Presentation (Week of Christmas Holiday)

    December 27, 2019 @ 1:00 pm - 2:00 pm
  • January 2020

  • Fri 3

    Grand Rounds January 3: No Presentation (New Year’s Holiday)

    January 3, 2020 @ 1:00 pm - 2:00 pm
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