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Living Textbook of
Pragmatic Clinical Trials

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Rethinking Clinical Trials

A Living Textbook of Pragmatic Clinical Trials

  • Design
    • What is a Pragmatic Clinical Trial?
    • Decentralized Pragmatic Clinical Trials
    • Developing a Compelling Grant Application
    • Experimental Designs and Randomization Schemes
    • Endpoints and Outcomes
    • Analysis Plan
    • Using Electronic Health Record Data
    • Building Partnerships and Teams to Ensure a Successful Trial
    • Intervention Delivery and Complexity
    • Patient Engagement
  • Data, Tools & Conduct
    • Assessing Feasibility
    • Acquiring Real-World Data
    • Assessing Fitness-for-Use of Real-World Data
    • Study Startup
    • Participant Recruitment
    • Monitoring Intervention Fidelity and Adaptations
    • Patient-Reported Outcomes
    • Clinical Decision Support
    • Mobile Health
    • Electronic Health Records–Based Phenotyping
    • Navigating the Unknown
  • Dissemination & Implementation
    • Data Sharing and Embedded Research
    • Dissemination Approaches for Different Audiences
    • Implementation
    • End-of-Trial Decision-Making
  • Ethics & Regulatory
    • Privacy Considerations
    • Identifying Those Engaged in Research
    • Collateral Findings
    • Consent, Disclosure, and Non-Disclosure
    • Data and Safety Monitoring
    • Ethical Considerations of Data Sharing in Pragmatic Clinical Trials
    • Ethics for AI and ML
    • IRB Responsibilities and Procedures
10 events found.

Events

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  • December 2019

  • Fri 13

    Grand Rounds December 13: EMBED Update: Challenges and Solutions

    December 13, 2019 @ 1:00 pm - 2:00 pm

    Speakers: Edward R. Melnick, MD, MHS Assistant Professor of Emergency Medicine Program Director, Yale-VA Clinical Informatics Fellowship Program Principal Investigator, EMBED Trial Gail D’Onofrio, MD Professor & Chair Department of Emergency Medicine Yale School of Medicine Topic: EMBED Update: Challenges and Solutions Date: Friday, December 13, 2019, 1:00-2:00 p.m. ET Meeting Info: To check whether […]

  • Thu 19

    IMPACT Collaboratory Grand Rounds December 19: Stepped wedge cluster trials: what, how, and when?

    December 19, 2019 @ 12:00 pm - 1:00 pm

    Speakers:  Monica Taljaard, PhD Senior Scientist, Ottawa Hospital Research Institute Associate Professor, University of Ottawa Topic:  Stepped wedge cluster trials: what, how, and when? Date: Thursday, December 19, 2019, 12:00-1:00 […]

  • Fri 20

    Grand Rounds December 20: No Presentation (Holiday Break)

    December 20, 2019 @ 1:00 pm - 2:00 pm
  • Fri 27

    Grand Rounds December 27: No Presentation (Week of Christmas Holiday)

    December 27, 2019 @ 1:00 pm - 2:00 pm
  • January 2020

  • Fri 3

    Grand Rounds January 3: No Presentation (New Year’s Holiday)

    January 3, 2020 @ 1:00 pm - 2:00 pm
  • Fri 10

    Grand Rounds January 10: Pragmatic Trials of Behavioral Economic Interventions to Increase Colorectal Cancer Screening

    January 10, 2020 @ 1:00 pm - 2:00 pm

    Speaker: Shivan Mehta, MD, MBA, MSHP Assistant Professor of Medicine and Health Policy University of Pennsylvania Topic: Pragmatic Trials of Behavioral Economic Interventions to Increase Colorectal Cancer Screening Date: Friday, […]

  • Fri 17

    Grand Rounds January 17: Assessment of the Human Systemic Absorption of Sunscreen Active Ingredients: FDA-Sponsored Randomized Clinical Trial

    January 17, 2020 @ 1:00 pm - 2:00 pm

    Speaker: Murali Matta, MPharm, PhD Bioanalytical Lead Division of Applied Regulatory Science Office of Clinical Pharmacology Food and Drug Administration Topic: Assessment of the Human Systemic Absorption of Sunscreen Active […]

  • Thu 23

    IMPACT Collaboratory Grand Rounds January 23: Using a Pilot to Test and Refine Your Measurement Strategy

    January 23, 2020 @ 12:00 pm - 1:00 pm

    Speakers:  Ellen McCreedy, PhD, MPH Assistant Professor, Brown University School of Public Health Topic: Using a Pilot to Test and Refine Your Measurement Strategy Date: Thursday, January 23, 2020, 12:00-1:00 […]

  • Fri 24

    Grand Rounds January 24: Cardiovascular Trials Over 2 Decades: Progress on Pragmatism?

    January 24, 2020 @ 1:00 pm - 2:00 pm

    Speaker: Justin A. Ezekowitz, MBBCh, MSc Professor, Department of Medicine Co-Director, Canadian VIGOUR Centre Director, Cardiovascular Research, University of Alberta Cardiologist, Mazankowski Alberta Heart Institute Topic: Cardiovascular Trials Over 2 Decades: […]

  • Fri 31

    Living Textbook Grand Rounds Series January 31: Part 1-Pragmatic Clinical Trials: How Do I Start?

    January 31, 2020 @ 1:00 pm - 2:00 pm

    Speakers: Greg Simon, MD, MPH Senior Investigator Kaiser Permanente Washington Health Research Institute Lesley H. Curtis, PhD Chair and Professor Department of Population Health Sciences Duke University School of Medicine […]

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