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Living Textbook of
Pragmatic Clinical Trials

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Access the latest information on COVID-19 for clinical researchers
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Rethinking Clinical Trials

A Living Textbook of Pragmatic Clinical Trials

  • Design
    • What is a Pragmatic Clinical Trial?
    • Decentralized Pragmatic Clinical Trials
    • Developing a Compelling Grant Application
    • Experimental Designs and Randomization Schemes
    • Endpoints and Outcomes
    • Analysis Plan
    • Using Electronic Health Record Data
    • Building Partnerships and Teams to Ensure a Successful Trial
    • Intervention Delivery and Complexity
    • Patient Engagement
  • Data, Tools & Conduct
    • Assessing Feasibility
    • Acquiring Real-World Data
    • Assessing Fitness-for-Use of Real-World Data
    • Study Startup
    • Participant Recruitment
    • Monitoring Intervention Fidelity and Adaptations
    • Patient-Reported Outcomes
    • Clinical Decision Support
    • Mobile Health
    • Electronic Health Records–Based Phenotyping
    • Navigating the Unknown
  • Dissemination & Implementation
    • Data Sharing and Embedded Research
    • Dissemination Approaches for Different Audiences
    • Implementation
    • End-of-Trial Decision-Making
  • Ethics & Regulatory
    • Privacy Considerations
    • Identifying Those Engaged in Research
    • Collateral Findings
    • Consent, Disclosure, and Non-Disclosure
    • Data and Safety Monitoring
    • Ethical Considerations of Data Sharing in Pragmatic Clinical Trials
    • Ethics for AI and ML
    • IRB Responsibilities and Procedures
10 events found.

Events

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  • January 2020

  • Fri 3

    Grand Rounds January 3: No Presentation (New Year’s Holiday)

    January 3, 2020 @ 1:00 pm - 2:00 pm
  • Fri 10

    Grand Rounds January 10: Pragmatic Trials of Behavioral Economic Interventions to Increase Colorectal Cancer Screening

    January 10, 2020 @ 1:00 pm - 2:00 pm

    Speaker: Shivan Mehta, MD, MBA, MSHP Assistant Professor of Medicine and Health Policy University of Pennsylvania Topic: Pragmatic Trials of Behavioral Economic Interventions to Increase Colorectal Cancer Screening Date: Friday, […]

  • Fri 17

    Grand Rounds January 17: Assessment of the Human Systemic Absorption of Sunscreen Active Ingredients: FDA-Sponsored Randomized Clinical Trial

    January 17, 2020 @ 1:00 pm - 2:00 pm

    Speaker: Murali Matta, MPharm, PhD Bioanalytical Lead Division of Applied Regulatory Science Office of Clinical Pharmacology Food and Drug Administration Topic: Assessment of the Human Systemic Absorption of Sunscreen Active […]

  • Thu 23

    IMPACT Collaboratory Grand Rounds January 23: Using a Pilot to Test and Refine Your Measurement Strategy

    January 23, 2020 @ 12:00 pm - 1:00 pm

    Speakers:  Ellen McCreedy, PhD, MPH Assistant Professor, Brown University School of Public Health Topic: Using a Pilot to Test and Refine Your Measurement Strategy Date: Thursday, January 23, 2020, 12:00-1:00 […]

  • Fri 24

    Grand Rounds January 24: Cardiovascular Trials Over 2 Decades: Progress on Pragmatism?

    January 24, 2020 @ 1:00 pm - 2:00 pm

    Speaker: Justin A. Ezekowitz, MBBCh, MSc Professor, Department of Medicine Co-Director, Canadian VIGOUR Centre Director, Cardiovascular Research, University of Alberta Cardiologist, Mazankowski Alberta Heart Institute Topic: Cardiovascular Trials Over 2 Decades: […]

  • Fri 31

    Living Textbook Grand Rounds Series January 31: Part 1-Pragmatic Clinical Trials: How Do I Start?

    January 31, 2020 @ 1:00 pm - 2:00 pm

    Speakers: Greg Simon, MD, MPH Senior Investigator Kaiser Permanente Washington Health Research Institute Lesley H. Curtis, PhD Chair and Professor Department of Population Health Sciences Duke University School of Medicine […]

  • February 2020

  • Fri 7

    Grand Rounds February 7: Using Nudges to Improve the Delivery of Health Care

    February 7, 2020 @ 1:00 pm - 2:00 pm

    Speaker: Mitesh S. Patel, MD, MBA Ralph Muller Presidential Assistant Professor Perelman School of Medicine & Wharton School University of Pennsylvania Director, Penn Medicine Nudge Unit Topic: Using Nudges to […]

  • Fri 14

    Grand Rounds February 14: Do Our Current Research Models Meet the Needs of a Learning Health Care System?

    February 14, 2020 @ 1:00 pm - 2:00 pm

    Speaker: David Atkins, MD, MPH Director, Health Services Research and Development Office of Research and Development Department of Veterans Affairs Topic: Do Our Current Research Models Meet the Needs of […]

  • Thu 20

    IMPACT Collaboratory Grand Rounds February 20: Modifications and waivers of informed consent in pragmatic clinical trials

    February 20, 2020 @ 12:00 pm - 1:00 pm

    Speakers:  Jason Karlawish, MD Professor of Medicine, Medical Ethics and Health Policy, and Neurology Co-Director, Penn Memory Center, University of Pennsylvania IMPACT Regulation and Ethics Core Leader Topic: Modifications and […]

  • Fri 21

    Grand Rounds February 21: Nudge Study Updates

    February 21, 2020 @ 1:00 pm - 2:00 pm

    Speakers: Michael Ho, MD, PhD Professor of Medicine, University of Colorado School of Medicine Staff Cardiologist, Rocky Mountain Regional VA Medical Center Sheana Bull, PhD, MPH Professor, Colorado School of Public Health Director, mHealth Impact Laboratory Topic: Nudge Study Updates Date: Friday, February 21, 2020, 1:00-2:00 p.m. ET Meeting Info: To check whether you have […]

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