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Living Textbook of
Pragmatic Clinical Trials

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Rethinking Clinical Trials

A Living Textbook of Pragmatic Clinical Trials

  • Design
    • What is a Pragmatic Clinical Trial?
    • Decentralized Pragmatic Clinical Trials
    • Developing a Compelling Grant Application
    • Experimental Designs and Randomization Schemes
    • Endpoints and Outcomes
    • Analysis Plan
    • Using Electronic Health Record Data
    • Building Partnerships and Teams to Ensure a Successful Trial
    • Intervention Delivery and Complexity
    • Patient Engagement
  • Data, Tools & Conduct
    • Assessing Feasibility
    • Acquiring Real-World Data
    • Assessing Fitness-for-Use of Real-World Data
    • Study Startup
    • Participant Recruitment
    • Monitoring Intervention Fidelity and Adaptations
    • Patient-Reported Outcomes
    • Clinical Decision Support
    • Mobile Health
    • Electronic Health Records–Based Phenotyping
    • Navigating the Unknown
  • Dissemination & Implementation
    • Data Sharing and Embedded Research
    • Dissemination Approaches for Different Audiences
    • Implementation
    • End-of-Trial Decision-Making
  • Ethics & Regulatory
    • Privacy Considerations
    • Identifying Those Engaged in Research
    • Collateral Findings
    • Consent, Disclosure, and Non-Disclosure
    • Data and Safety Monitoring
    • Ethical Considerations of Data Sharing in Pragmatic Clinical Trials
    • Ethics for AI and ML
    • IRB Responsibilities and Procedures
10 events found.

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  • April 2016

  • Fri 15

    Considerations in the Evaluation and Determination of Minimal Risk in Research Studies

    April 15, 2016 @ 1:00 pm - 2:00 pm

    Presenter: Lantos, John Slides: Slides Video: Grand-Rounds-04-15-16

  • Fri 22

    Challenges and Opportunities for Using Common PRO Measures in Comparative Effectiveness Research

    April 22, 2016 @ 1:00 pm - 2:00 pm

    Presenter: Laws, Reesa Slides: Slides Video: Grand-Rounds-04-22-16

  • Fri 29

    PCORnet and CTSA Network: Synergizing National Initiatives

    April 29, 2016 @ 1:00 pm - 2:00 pm

    Presenter: Gersing, Ken Slides: Slides Video: Grand-Rounds-04-29-16

  • May 2016

  • Fri 6

    Clinician Engagement in the NIH Collaboratory and Beyond

    May 6, 2016 @ 1:00 pm - 2:00 pm

    Presenter: Tambor, Ellen Slides: Slides Video: Grand-Rounds-05-06-16

  • Fri 13

    ABATE Infection Trial: Backstage Tour

    May 13, 2016 @ 1:00 pm - 2:00 pm

    Presenter: Septimus, Ed Slides: Slides Video: Grand-Rounds-05-13-16

  • Fri 20

    Altered Informed Consent in Pragmatic Clinical Trials

    May 20, 2016 @ 1:00 pm - 2:00 pm

    Presenter: McKinney, Ross Slides: Slides Video: Grand-Rounds-05-20-16

  • June 2016

  • Fri 3

    CTSA Trial Innovation Network: Early Vision & Goals

    June 3, 2016 @ 1:00 pm - 2:00 pm

    Presenter: Shah, Monica Slides: Slides Video: Grand-Rounds-06-03-16

  • Fri 10

    Pragmatic Trials in Dialysis: What’s Next After the TiME Trial?

    June 10, 2016 @ 1:00 pm - 2:00 pm

    Presenter: Dember, Laura Slides: Slides Video: Grand-Rounds-06-10-16

  • Fri 17

    Oversight on the Borderline: Quality Improvement and Pragmatic Research

    June 17, 2016 @ 1:00 pm - 2:00 pm

    Presenter: Finkelstein, Jonathan Slides: Slides Video: Grand-Rounds-06-17-16

  • Fri 24

    Recommendations for Recruitment: Moving Recruitment Planning Upstream To Reduce Barriers to Participation

    June 24, 2016 @ 1:00 pm - 2:00 pm

    Presenter: McKee, Kelly Slides: Slides Video: Grand-Rounds-06-24-16

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