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Living Textbook of
Pragmatic Clinical Trials

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Access the latest information on COVID-19 for clinical researchers
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Rethinking Clinical Trials

A Living Textbook of Pragmatic Clinical Trials

  • Design
    • What is a Pragmatic Clinical Trial?
    • Decentralized Pragmatic Clinical Trials
    • Developing a Compelling Grant Application
    • Experimental Designs and Randomization Schemes
    • Endpoints and Outcomes
    • Analysis Plan
    • Using Electronic Health Record Data
    • Building Partnerships and Teams to Ensure a Successful Trial
    • Intervention Delivery and Complexity
    • Patient Engagement
  • Data, Tools & Conduct
    • Assessing Feasibility
    • Acquiring Real-World Data
    • Assessing Fitness-for-Use of Real-World Data
    • Study Startup
    • Participant Recruitment
    • Monitoring Intervention Fidelity and Adaptations
    • Patient-Reported Outcomes
    • Clinical Decision Support
    • Mobile Health
    • Electronic Health Records–Based Phenotyping
    • Navigating the Unknown
  • Dissemination & Implementation
    • Data Sharing and Embedded Research
    • Dissemination Approaches for Different Audiences
    • Implementation
    • End-of-Trial Decision-Making
  • Ethics & Regulatory
    • Privacy Considerations
    • Identifying Those Engaged in Research
    • Collateral Findings
    • Consent, Disclosure, and Non-Disclosure
    • Data and Safety Monitoring
    • Ethical Considerations of Data Sharing in Pragmatic Clinical Trials
    • Ethics for AI and ML
    • IRB Responsibilities and Procedures
10 events found.

Events

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  • September 2023

  • Fri 15

    Grand Rounds September 15, 2023: Effect of Financial Incentives and Default Options on Food Choices of Adults With Low Income in Online Retail Settings (Pasquale Rummo, PhD, MPH)

    September 15, 2023 @ 1:00 pm - 2:00 pm

    Speaker: Pasquale Rummo, PhD, MPH Associate Professor NYU Grossman School of Medicine Topic: Effect of Financial Incentives and Default Options on Food Choices of Adults With Low Income in Online Retail Settings Date: Friday, September 15, 2023, 1:00-2:00 p.m. ET To join the online meeting: Click the Zoom Meeting link below: https://duke.zoom.us/j/96153659804?pwd=VmNJVDE5VmtFbUFHY0lZeTM1K0Y5QT09 Meeting ID: 961 […]

  • Fri 22

    Grand Rounds September 22, 2023: Community Health Workers in Early Childhood Well-Child Care (Tumaini Rucker Coker, MD, MBA)

    September 22, 2023 @ 1:00 pm - 2:00 pm

    Speaker: Tumaini Rucker Coker, MD, MBA Professor of Pediatrics Division Head for General Pediatrics University of Washington Department of Pediatrics Seattle Children's Hospital Topic: Community Health Workers in Early Childhood Well-Child Care Date: Friday, September 22, 2023, 1:00-2:00 p.m. ET To join the online meeting: Click the Zoom Meeting link below: https://duke.zoom.us/j/96153659804?pwd=VmNJVDE5VmtFbUFHY0lZeTM1K0Y5QT09 Meeting ID: 961 […]

  • Fri 29

    Grand Rounds September 29, 2023: Navigating the Use of Patient-Reported Outcomes in Research and Practice: The PROTEUS Consortium (Claire Snyder, PhD; Norah Crossnohere, PhD; Anne Schuster, PhD)

    September 29, 2023 @ 1:00 pm - 2:00 pm

    Speakers: Claire Snyder, PhD Professor Johns Hopkins Schools of Medicine and Public Health Norah Crossnohere, PhD Assistant Professor Ohio State University College of Medicine Anne Schuster, PhD Research Scientist Ohio State University College of Medicine Topic: Navigating the Use of Patient-Reported Outcomes in Research and Practice: The PROTEUS Consortium Date: Friday, September 29, 2023, 1:00-2:00 […]

  • October 2023

  • Fri 6

    Grand Rounds Biostatistics Series October 6, 2023: Hybrid Studies Should Not Sacrifice Rigorous Methods (David M. Murray, PhD; Moderator: Jonathan Moyer, PhD)

    October 6, 2023 @ 1:00 pm - 2:00 pm

    Speaker: David M. Murray, PhD NIH Associate Director for Prevention and Director, NIH Office of Disease Prevention Moderator: Jonathan C. Moyer, PhD Statistician, NIH Office of Disease Prevention Topic: Hybrid Studies Should Not Sacrifice Rigorous Methods Date: Friday, October 6, 2023, 1:00-2:00 p.m. ET To join the online meeting: Click the Zoom Meeting link below: https://duke.zoom.us/j/96153659804?pwd=VmNJVDE5VmtFbUFHY0lZeTM1K0Y5QT09 Meeting […]

  • Fri 13

    Grand Rounds October 13, 2023: Incorporating Social Determinants of Health Into PCORnet (Keith Marsolo, PhD)

    October 13, 2023 @ 1:00 pm - 2:00 pm

    Speaker: Keith Marsolo, PhD Associate Professor, Department of Population Health Sciences, Duke University School of Medicine Topic: Incorporating Social Determinants of Health Into PCORnet Date: Friday, October 13, 2023, 1:00-2:00 p.m. ET To join the online meeting: Click the Zoom Meeting link below: https://duke.zoom.us/j/96153659804?pwd=VmNJVDE5VmtFbUFHY0lZeTM1K0Y5QT09 Meeting ID: 961 5365 9804 Passcode: 12345 One tap mobile +16468769923,,96153659804#,,,,*12345# […]

  • Fri 20

    Grand Rounds October 20, 2023: A National Initiative to Eliminate Hepatitis C in the United States – Why This Matters to Clinical Trialists (Rachael L. Fleurence, PhD, MSc; Joshua M. Sharfstein, MD)

    October 20, 2023 @ 1:00 pm - 2:00 pm

    Speaker: Rachael L. Fleurence, PhD, MSc  Senior Advisor National Institutes of Health Joshua M. Sharfstein, MD Vice Dean for Public Health Practice and Community Engagement Director, Bloomberg American Health Initiative Professor of the Practice in Health Policy and Management Topic: A National Initiative to Eliminate Hepatitis C in the United States - Why This Matters […]

  • Fri 27

    Grand Rounds October 27, 2023: Digital, Decentralized and Democratized: Lessons From The Yale PaxLC Trial (Harlan M. Krumholz, MD, SM)

    October 27, 2023 @ 1:00 pm - 2:00 pm

    Speaker: Harlan M. Krumholz, MD, SM Harold H. Hines, Jr. Professor of Medicine Department of Internal Medicine Section of Cardiovascular Medicine Yale University School of Medicine Director, Yale-New Haven Hospital […]

  • November 2023

  • Fri 3

    Grand Rounds Biostatistics Series November 3, 2023: The Perils and Pitfalls of Complex Clustering in Pragmatic Trials (Jonathan Moyer, PhD; Moderator: Andrea Cook, PhD)

    November 3, 2023 @ 1:00 pm - 2:00 pm

    Speaker: Jonathan C. Moyer, PhD Statistician, NIH Office of Disease Prevention Moderator: Andrea J. Cook, PhD Senior Biostatistics Investigator, Kaiser Permanente Washington Health Research Institute Topic: The Perils and Pitfalls […]

  • Fri 10

    Grand Rounds November 10, 2023: No Presentation (Holiday)

    November 10, 2023 @ 1:00 pm - 2:00 pm
  • Fri 17

    Grand Rounds November 17, 2023: Personalized Patient Data and Behavioral Nudges to Improve Adherence to Chronic Cardiovascular Medications: Results from the Nudge Study (Michael Ho, MD, PhD; Sheana Bull, PhD)

    November 17, 2023 @ 1:00 pm - 2:00 pm

    Speakers: Michael Ho, MD, PhD University of Colorado Sheana Bull, PhD University of Colorado Topic: Personalized Patient Data and Behavioral Nudges to Improve Adherence to Chronic Cardiovascular Medications: Results from […]

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