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Living Textbook of
Pragmatic Clinical Trials

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Rethinking Clinical Trials

A Living Textbook of Pragmatic Clinical Trials

  • Design
    • What is a Pragmatic Clinical Trial?
    • Decentralized Pragmatic Clinical Trials
    • Developing a Compelling Grant Application
    • Experimental Designs and Randomization Schemes
    • Endpoints and Outcomes
    • Analysis Plan
    • Using Electronic Health Record Data
    • Building Partnerships and Teams to Ensure a Successful Trial
    • Intervention Delivery and Complexity
    • Patient Engagement
  • Data, Tools & Conduct
    • Assessing Feasibility
    • Acquiring Real-World Data
    • Assessing Fitness-for-Use of Real-World Data
    • Study Startup
    • Participant Recruitment
    • Monitoring Intervention Fidelity and Adaptations
    • Patient-Reported Outcomes
    • Clinical Decision Support
    • Mobile Health
    • Electronic Health Records–Based Phenotyping
    • Navigating the Unknown
  • Dissemination & Implementation
    • Data Sharing and Embedded Research
    • Dissemination Approaches for Different Audiences
    • Implementation
    • End-of-Trial Decision-Making
  • Ethics & Regulatory
    • Privacy Considerations
    • Identifying Those Engaged in Research
    • Collateral Findings
    • Consent, Disclosure, and Non-Disclosure
    • Data and Safety Monitoring
    • Ethical Considerations of Data Sharing in Pragmatic Clinical Trials
    • Ethics for AI and ML
    • IRB Responsibilities and Procedures
10 events found.

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  • July 2016

  • Fri 15

    FDA and Pragmatic Clinical Trials of Marketed Medical Products

    July 15, 2016 @ 1:00 pm - 2:00 pm

    Presenter: Anderson, Monique Slides: Slides Video: Grand-Rounds-07-15-16

  • Fri 22

    Preparing for a Pragmatic Influenza Vaccine Clinical Trial: A One-shot Deal

    July 22, 2016 @ 1:00 pm - 2:00 pm

    Presenter: Vardeny, Orly Slides: Slides Video: Grand-Rounds-07-22-16

  • Fri 29

    Accessing PCORnet’s Data and Network Resources

    July 29, 2016 @ 1:00 pm - 2:00 pm

    Presenter: Forrest, Christopher Slides: Slides Video: Grand-Rounds-07-29-16

  • August 2016

  • Fri 5

    Embedded Pragmatic Trials: Triumphs and Tribulations

    August 5, 2016 @ 1:00 pm - 2:00 pm

    Presenter: Ramsberg, Joakim Slides: Slides Video: Grand-Rounds-08-05-16

  • Fri 12

    Sharing Data: Methods to Increase Data Sharing and Improve Human Health

    August 12, 2016 @ 1:00 pm - 2:00 pm

    Presenter: Patel, Manesh Slides: Slides Video: Grand-Rounds-08-12-16

  • Fri 19

    Privacy and Confidentiality in Pragmatic Clinical Trials

    August 19, 2016 @ 1:00 pm - 2:00 pm

    Presenter: Rubel, Alan Slides: Slides Video: Grand-Rounds-08-19-16

  • Fri 26

    Updates from the Phenotypes, Data Standards, and Data Quality Core of the NIH HCS Research Collaboratory

    August 26, 2016 @ 1:00 pm - 2:00 pm

    Presenter: Richesson, Rachel Slides: SlidesVideo: Grand-Rounds-08-26-16

  • September 2016

  • Fri 9

    Million Veteran Program: A Mega-Cohort Within a Healthcare System

    September 9, 2016 @ 1:00 pm - 2:00 pm

    Presenter: Gaziano, Michael Slides: Slides Video: Grand-Rounds-09-09-16.aspx

  • Fri 16

    PCORnet Building Trustworthiness

    September 16, 2016 @ 1:00 pm - 2:00 pm

    Presenter: Williams, Neely Slides: Slides Video: Grand-Rounds-09-16-16

  • Fri 23

    ICD-Pieces: Early Implementation and Progress

    September 23, 2016 @ 1:00 pm - 2:00 pm

    Presenter: Oliver, George Slides: Slides Video: Grand-Rounds-09-23-16

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