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Living Textbook of
Pragmatic Clinical Trials

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Access the latest information on COVID-19 for clinical researchers
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Rethinking Clinical Trials

A Living Textbook of Pragmatic Clinical Trials

  • Design
    • What is a Pragmatic Clinical Trial?
    • Decentralized Pragmatic Clinical Trials
    • Developing a Compelling Grant Application
    • Experimental Designs and Randomization Schemes
    • Endpoints and Outcomes
    • Analysis Plan
    • Using Electronic Health Record Data
    • Building Partnerships and Teams to Ensure a Successful Trial
    • Intervention Delivery and Complexity
    • Patient Engagement
  • Data, Tools & Conduct
    • Assessing Feasibility
    • Acquiring Real-World Data
    • Assessing Fitness-for-Use of Real-World Data
    • Study Startup
    • Participant Recruitment
    • Monitoring Intervention Fidelity and Adaptations
    • Patient-Reported Outcomes
    • Clinical Decision Support
    • Mobile Health
    • Electronic Health Records–Based Phenotyping
    • Navigating the Unknown
  • Dissemination & Implementation
    • Data Sharing and Embedded Research
    • Dissemination Approaches for Different Audiences
    • Implementation
    • End-of-Trial Decision-Making
  • Ethics & Regulatory
    • Privacy Considerations
    • Identifying Those Engaged in Research
    • Collateral Findings
    • Consent, Disclosure, and Non-Disclosure
    • Data and Safety Monitoring
    • Ethical Considerations of Data Sharing in Pragmatic Clinical Trials
    • Ethics for AI and ML
    • IRB Responsibilities and Procedures
10 events found.

Events

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  • March 2024

  • Fri 22

    Grand Rounds March 22, 2024: Early Diagnosis and Assessment of Autism Via Objective Measurements of Social Visual Engagement (Warren Jones, PhD)

    March 22, 2024 @ 1:00 pm - 2:00 pm

    Speaker: Warren Jones, PhD Director of Research, Marcus Autism Center Children's Healthcare of Atlanta Norman Nien Distinguished Chair in Autism Associate Professor, Dept. of Pediatrics Emory University School of Medicine Title: Early Diagnosis and Assessment of Autism Via Objective Measurements of Social Visual Engagement Date: Friday, March 22, 2024, 1:00-2:00 p.m. ET To join the […]

  • Wed 27

    Prevention in Focus Webinar Series: Is It More than PMS? Learn About PMDD

    March 27, 2024 @ 1:00 pm - 2:00 pm

    Prevention in Focus Webinar Series: It More than PMS? Learn About PMDD Marybeth Bohn, International Association for Premenstrual Disorders Sandi MacDonald, International Association for Premenstrual Disorders Register for the webinar […]

  • Fri 29

    Grand Rounds March 29, 2024: Effect Of A Multicomponent Intervention to Improve Patient Access to Kidney Transplant and Living Kidney Donation: A Pragmatic, Cluster-Randomized Trial (Amit Garg, MD, MA, FRCPC, FACP, PhD; Stephanie N. Dixon, PhD, MSc)

    March 29, 2024 @ 1:00 pm - 2:00 pm

    Speakers: Amit Garg, MD, MA (Education) FRCPC, FACP, PhD Associate Dean, Clinical Research, Schulich School of Medicine and Dentistry Lead, Institute for Clinical Evaluative Sciences Kidney, Dialysis and Transplantation Provincial Program Director, Institute for Clinical Evaluative Sciences (ICES) Western Facility Nephrologist, London Health Sciences Centre Professor, Medicine, Epidemiology & Biostatistics, Western University  Stephanie N. Dixon, […]

  • April 2024

  • Wed 3

    NIH Clinical Center Grand Rounds: “How Can We Respect the Dead?”

    April 3, 2024 @ 12:00 pm - 1:00 pm

    NIH Clinical Center Grand Rounds: “How Can We Respect the Dead?” Discussant: Neal Dickert MD, PhD Thomas R. Williams Professor of Medicine, Emory University https://videocast.nih.gov/

  • Fri 5

    Grand Rounds April 5, 2024: A New Look at P Values for Randomized Clinical Trials (Erik van Zwet, PhD)

    April 5, 2024 @ 1:00 pm - 2:00 pm

    Speaker: Erik van Zwet, PhD Department of Biomedical Data Sciences Leiden University Medical Center, the Netherlands Title: A New Look at P Values for Randomized Clinical Trials Date: Friday, April 5, 2024, 1:00-2:00 p.m. ET To join the online meeting: Click the Zoom Meeting link below: https://duke.zoom.us/j/98292370425?pwd=S05sOU42WXp3NXNjK0ZkczN0WXpHUT09 Meeting ID: 982 9237 0425 Passcode: 237056 One […]

  • Fri 5

    2024 Allan Donner Lecture: The Unit of Inference in Cluster Randomized Trials

    April 5, 2024 @ 1:30 pm - 2:30 pm

    2024 Allan Donner Lecture: Dr. Fan Li Date: Friday, April 5 Time: 1:30 pm - 2:30 pm Location: PHFM 3015 (Western Centre for Public Health and Family Medicine) or Zoom (link may be […]

  • Fri 12

    Grand Rounds April 12, 2024: Primary Palliative Care for Emergency Medicine, a Cluster Randomized Stepped-Wedge Trial Across 33 Emergency Departments (Corita R. Grudzen, MD, MSHS, FACEP)

    April 12, 2024 @ 1:00 pm - 2:00 pm

    Speaker: Corita R. Grudzen, MD, MSHS, FACEP Fern Grayer Chair in Oncology Care and the Patient Experience Division Head, Supportive and Acute Care Services Memorial Sloan Kettering Cancer Center Professor of Emergency Medicine Weill Cornell Medical College Title: Primary Palliative Care for Emergency Medicine, A Cluster Randomized Stepped-Wedge Trial Across 33 Emergency Departments Date: Friday, […]

  • Fri 19

    Grand Rounds April 19, 2024: The Yale Open Data Access (YODA) Project: 10 Years of Clinical Trial Data Sharing (Joseph S. Ross, MD, MHS)

    April 19, 2024 @ 1:00 pm - 2:00 pm

    Speaker: Joseph S. Ross, MD, MHS Professor of Medicine and Public Health Yale University Title: The Yale Open Data Access (YODA) Project: 10 Years of Clinical Trial Data Sharing Date: Friday, April 19, 2024, 1:00-2:00 p.m. ET To join the online meeting: Click the Zoom Meeting link below: https://duke.zoom.us/j/93696931854?pwd=dXUySnkzYkNwK1NQeHVHWjRKR1ptUT09 Meeting ID: 936 9693 1854 Passcode: […]

  • Fri 26

    Grand Rounds April 26, 2024: Waiver or Alteration of Informed Consent for Minimal Risk Clinical Investigations – FDA Regulation Development and Research Landscape (Lauren Milner, PhD; Jonathan Casey, MD, MSCI; Matthew Semler, MD, MSCI)

    April 26, 2024 @ 1:00 pm - 2:00 pm

    Speakers: Lauren Milner, PhD Office of Clinical Policy US Food and Drug Administration  (FDA) Jonathan Casey, M.D., MSCI Assistant Professor, Division of Pulmonary and Critical Care Medicine Vanderbilt University Medical Center Director, Coordinating Center Pragmatic Critical Care Research Group Matthew Semler, M.D., MSCI Associate Professor, Division of Pulmonary and Critical Care Medicine Vanderbilt University Medical […]

  • May 2024

  • Fri 3

    Grand Rounds May 3, 2024: Comparative Effectiveness of Kidney Stone Surgery in Pediatric Patients: The PKIDS Trial (Gregory Tasian, MD, MSc, MSCE)

    May 3, 2024 @ 1:00 pm - 2:00 pm

    Speaker: Gregory Tasian, MD, MSc, MSCE Associate Professor of Surgery and Epidemiology Children’s Hospital of Philadelphia Title: Comparative Effectiveness of Kidney Stone Surgery in Pediatric Patients: The PKIDS Trial Date: Friday, May 3, 2024, 1:00-2:00 p.m. ET To join the online meeting: Click the Zoom Meeting link below: https://duke.zoom.us/j/92733839047?pwd=MkNISkRqK2RsQmVxK254SVdOQ2plZz09 Meeting ID: 927 3383 9047 Passcode: […]

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