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Living Textbook of
Pragmatic Clinical Trials

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Access the latest information on COVID-19 for clinical researchers
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Rethinking Clinical Trials

A Living Textbook of Pragmatic Clinical Trials

  • Design
    • What is a Pragmatic Clinical Trial?
    • Decentralized Pragmatic Clinical Trials
    • Developing a Compelling Grant Application
    • Experimental Designs and Randomization Schemes
    • Endpoints and Outcomes
    • Analysis Plan
    • Using Electronic Health Record Data
    • Building Partnerships and Teams to Ensure a Successful Trial
    • Intervention Delivery and Complexity
    • Patient Engagement
  • Data, Tools & Conduct
    • Assessing Feasibility
    • Acquiring Real-World Data
    • Assessing Fitness-for-Use of Real-World Data
    • Study Startup
    • Participant Recruitment
    • Monitoring Intervention Fidelity and Adaptations
    • Patient-Reported Outcomes
    • Clinical Decision Support
    • Mobile Health
    • Electronic Health Records–Based Phenotyping
    • Navigating the Unknown
  • Dissemination & Implementation
    • Data Sharing and Embedded Research
    • Dissemination Approaches for Different Audiences
    • Implementation
    • End-of-Trial Decision-Making
  • Ethics & Regulatory
    • Privacy Considerations
    • Identifying Those Engaged in Research
    • Collateral Findings
    • Consent, Disclosure, and Non-Disclosure
    • Data and Safety Monitoring
    • Ethical Considerations of Data Sharing in Pragmatic Clinical Trials
    • Ethics for AI and ML
    • IRB Responsibilities and Procedures
10 events found.

Events

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  • February 2024

  • Fri 2

    Grand Rounds February 2, 2024: Strategies for Improving Public Understanding of the FDA and the Products It Regulates: Why Should We Care, and What Might We Do? (Susan C. Winckler, RPh, Esq)

    February 2, 2024 @ 1:00 pm - 2:00 pm

    Speaker: Susan C. Winckler, RPh, Esq Chief Executive Officer Reagan-Udall Foundation for the FDA Title: Strategies for Improving Public Understanding of the FDA and the Products It Regulates: Why Should […]

  • Wed 7

    NIH Clinical Center Grand Rounds: “Supported Decision-Making in Research”

    February 7, 2024 @ 12:00 pm - 1:00 pm

    NIH Clinical Center Grand Rounds: "Supported Decision-Making in Research" Discussant: Nina A. Kohn, JD David M. Levy Professor of Law Syracuse University College of Law; Distinguished Scholar in Elder Law […]

  • Fri 9

    Grand Rounds February 9, 2024: Pragmatic Recruitment of Underrepresented Groups – Experience From the Diuretic Comparison Project (Cynthia Hau, MPH)

    February 9, 2024 @ 1:00 pm - 2:00 pm

    Speaker: Cynthia Hau, MPH Statistician Boston Cooperative Studies Program Coordinating Center VA Boston Healthcare System Title: Pragmatic Recruitment of Underrepresented Groups – Experience From the Diuretic Comparison Project Date: Friday, […]

  • Fri 16

    Grand Rounds February 16, 2024: Clinical Implications of the MINT Trial: p=0.07 (Jeffrey Carson, MD, MACP)

    February 16, 2024 @ 1:00 pm - 2:00 pm

    Speaker: Jeffrey Carson, MD, MACP Principal Investigator and Study Chair MINT Trial Provost-New Brunswick, Rutgers Biomedical Health Sciences Distinguished Professor of Medicine Richard C. Reynolds, M.D. Chair in General Internal Medicine Rutgers, Robert […]

  • Fri 23

    Grand Rounds February 23, 2024: Virtual Vigilance: Monitoring of Decentralized Clinical Trials (Adrian Hernandez, MD; Christopher J. Lindsell, PhD)

    February 23, 2024 @ 1:00 pm - 2:00 pm

    Speakers: Adrian Hernandez, MD Executive Director, Duke Clinical Research Institute Vice Dean, Duke University School of Medicine Christopher J. Lindsell, PhD Professor and co-Chief of Biostatistics, Department of Biostatistics & Bioinformatics Director, Data Science and Biostatistics, Duke Clinical Research Institute Duke University School of Medicine Editor in Chief, Journal of Clinical and translational Science Title: […]

  • March 2024

  • Fri 1

    Grand Rounds March 1, 2024: Effect of an Intensive Food-as-Medicine Program on Health and Healthcare Use: Evidence From a Randomized Clinical Trial (Joseph Doyle, PhD)

    March 1, 2024 @ 1:00 pm - 2:00 pm

    Speaker: Joseph Doyle, PhD Erwin H. Schell Professor of Management and Applied Economics MIT Sloan School of Management Title: Effect of an Intensive Food-as-Medicine Program on Health and Healthcare Use: Evidence From a Randomized Clinical Trial Date: Friday, March 1, 2024, 1:00-2:00 p.m. ET To join the online meeting: Click the Zoom Meeting link below: […]

  • Fri 8

    Grand Rounds March 8, 2024: Public-Private Partnerships in the Trustworthy Health AI Ecosystem (Michael Pencina, PhD; Brian Anderson, MD)

    March 8, 2024 @ 1:00 pm - 2:00 pm

    Speakers: Michael Pencina, PhD Chief Data Scientist, Duke Health Professor of Biostatistics and Bioinformatics and Vice Dean for Data Science, Duke University School of Medicine Brian Anderson, MD CEO, Coalition for Health AI Title: Public-private Partnerships in the Trustworthy Health AI Ecosystem Date: Friday, March 8, 2024, 1:00-2:00 p.m. ET To join the online meeting: […]

  • Fri 15

    Grand Rounds March 15, 2024: The Effect of Antibiotic Choice on Renal Outcomes: The ACORN Trial (Edward Qian, MD, MSc)

    March 15, 2024 @ 1:00 pm - 2:00 pm

    Speaker: Edward Qian, MD, MSc Assistant Professor of Medicine Vanderbilt University Medical Center Division of Pulmonary and Critical Care Medicine Title: The Effect of Antibiotic Choice on Renal Outcomes: The ACORN Trial Date: Friday, March 15, 2024, 1:00-2:00 p.m. ET To join the online meeting: Click the Zoom Meeting link below: https://duke.zoom.us/j/97453499746?pwd=bXRuaGQ3V2R3ZWJQdUJlSTZGNGo2dz09 Meeting ID: 974 […]

  • Wed 20

    Mind the Gap Webinar Series: Deconstruction of the Type 2 Hybrid Effectiveness-Implementation Study Design that Uses Two Randomized Controlled Trials

    March 20, 2024 @ 12:00 pm - 1:00 pm

    Deconstruction of the Type 2 Hybrid Effectiveness-Implementation Study Design that Uses Two Randomized Controlled Trials Register now Presented byJune Stevens, Ph.D. March 20, 202412:00 noon–1:00 p.m. ET About the Webinar Implementation […]

  • Fri 22

    Grand Rounds March 22, 2024: Early Diagnosis and Assessment of Autism Via Objective Measurements of Social Visual Engagement (Warren Jones, PhD)

    March 22, 2024 @ 1:00 pm - 2:00 pm

    Speaker: Warren Jones, PhD Director of Research, Marcus Autism Center Children's Healthcare of Atlanta Norman Nien Distinguished Chair in Autism Associate Professor, Dept. of Pediatrics Emory University School of Medicine Title: Early Diagnosis and Assessment of Autism Via Objective Measurements of Social Visual Engagement Date: Friday, March 22, 2024, 1:00-2:00 p.m. ET To join the […]

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