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Living Textbook of
Pragmatic Clinical Trials

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Rethinking Clinical Trials

A Living Textbook of Pragmatic Clinical Trials

  • Design
    • What is a Pragmatic Clinical Trial?
    • Decentralized Pragmatic Clinical Trials
    • Developing a Compelling Grant Application
    • Experimental Designs and Randomization Schemes
    • Endpoints and Outcomes
    • Analysis Plan
    • Using Electronic Health Record Data
    • Building Partnerships and Teams to Ensure a Successful Trial
    • Intervention Delivery and Complexity
    • Patient Engagement
  • Data, Tools & Conduct
    • Assessing Feasibility
    • Acquiring Real-World Data
    • Assessing Fitness-for-Use of Real-World Data
    • Study Startup
    • Participant Recruitment
    • Monitoring Intervention Fidelity and Adaptations
    • Patient-Reported Outcomes
    • Clinical Decision Support
    • Mobile Health
    • Electronic Health Records–Based Phenotyping
    • Navigating the Unknown
  • Dissemination & Implementation
    • Data Sharing and Embedded Research
    • Dissemination Approaches for Different Audiences
    • Implementation
    • End-of-Trial Decision-Making
  • Ethics & Regulatory
    • Privacy Considerations
    • Identifying Those Engaged in Research
    • Collateral Findings
    • Consent, Disclosure, and Non-Disclosure
    • Data and Safety Monitoring
    • Ethical Considerations of Data Sharing in Pragmatic Clinical Trials
    • Ethics for AI and ML
    • IRB Responsibilities and Procedures
66 events found.

Events

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  • September 2018

  • Fri 28

    Grand Rounds September 28: Assessing and reducing risk of re-identification when sharing sensitive research datasets

    September 28, 2018 @ 1:00 pm - 2:00 pm

    Speakers: Gregory Simon MD, MPH Investigator Kaiser Permanente Washington Health Research Institute Deven McGraw, JD, MPH, LLM General Counsel & Chief Regulatory Officer Ciitizen (former HIPAA Deputy Director, HHS Office for Civil Rights) Khaled El Emam, PhD Department of Pediatrics University of Ottawa Children's Hospital of Eastern Ontario Research Institute Topic: Assessing and reducing risk […]

  • October 2018

  • Fri 5

    Grand Rounds October 5: Testing New Atrial Fibrillation Screening Methods at Scale

    October 5, 2018 @ 1:00 pm - 2:00 pm

    Speakers: Mintu Turakhia MD, MAS Associate Professor of Medicine. Stanford University Executive Director, Stanford Center for Digital Health Director of Cardiac Electrophysiology, VA Palo Alto Healthcare System Marco Perez MD Assistant Professor of Medicine, Stanford University Topic: Testing New Atrial Fibrillation Screening Methods at Scale Date: Friday, October 5, 2018, 1:00-2:00 p.m. ET Meeting Info: To […]

  • Fri 12

    Grand Rounds October 12: MDEpiNet RAPID and SPEED Projects: Leveraging Real World Evidence to Get Better, Faster, Cheaper Medical Devices for Physicians and Patients

    October 12, 2018 @ 1:00 pm - 2:00 pm

    Speakers: Renee Mitchell, MT(ASCP), CLS(NCA) Regulatory Affairs Boston Scientific Corporation, Inc. Terrie Reed, MSIE Senior Advisor for UDI Adoption US Food and Drug Administration (FDA) Roseann White, MA Director of Innovative Clinical Trial Statistics Duke Clinical Research Institute Topic: MDEpiNet RAPID and SPEED Projects: Leveraging Real World Evidence to Get Better, Faster, Cheaper Medical Devices for […]

  • Fri 19

    Grand Rounds October 19: A New Path Forward for Using Decentralized Clinical Trials

    October 19, 2018 @ 1:00 pm - 2:00 pm

    Speakers: Annemarie Forrest Clinical Trials Transformation Initiative (CTTI) Penny Randall, MD, MBA VP and Global Therapeutic Head, CNS, IQVIA Jeffry Florian, PhD Clinical Analyst, Office of New Drugs, FDA CDER Topic: A New Path Forward for Using Decentralized Clinical Trials Date: Friday, October 19, 2018, 1:00-2:00 p.m. ET Meeting Info: To check whether you have the appropriate […]

  • Fri 26

    Grand Rounds October 26: Making Measurements Meaningful

    October 26, 2018 @ 1:00 pm - 2:00 pm

    Speakers: Brian J. Zikmund-Fisher, Ph.D. Associate Professor of Health Behavior and Health Education University of Michigan Associate Director of the UM Center for Bioethics and Social Sciences in Medicine Topic: Making Measurements Meaningful Date: Friday, October 26, 1:00-2:00 p.m. ET Meeting Info: To check whether you have the appropriate players installed for UCF (Universal Communications Format) […]

  • November 2018

  • Fri 2

    Grand Rounds November 2: EMBED: Pragmatic Trial of User-Centered Clinical Decision Support to Implement Emergency Department-Initiated Buprenorphine for Opioid Use Disorder

    November 2, 2018 @ 1:00 pm - 2:00 pm

    Speakers: Ted Melnick, MD, MHS Assistant Professor of Emergency Medicine Program Director, ACGME Clinical Informatics Fellowship Yale School of Medicine Gail D’Onofrio, MD Professor and Chair of Emergency Medicine, Yale School of Medicine Physician-in-Chief of Emergency Services Yale-New Haven Hospital Topic: EMBED: Pragmatic Trial of User-Centered Clinical Decision Support to Implement Emergency Department-Initiated Buprenorphine for Opioid […]

  • Tue 6

    DCRI Research Forum: Dr. Jeffrey Jarvik on Lumbar Imaging with Reporting of Epidemiology (LIRE)

    November 6, 2018 @ 12:00 pm - 1:00 pm

    DCRI Research Forum  Dr. Jeffrey Jarvik on Lumbar Imaging with Reporting of Epidemiology (LIRE)  12:00 pm | Eastern Daylight Time (New York, GMT-04:00) | 1 hr. Meeting number (access code): 732 427 579 Meeting password: DCRI Join by phone: 1-650-479-3207 Call-in toll number (US/Canada) 1-855-244-8681 Call-in toll-free number (US/Canada) Toll-free calling restrictions Join from a video […]

  • Fri 9

    Grand Rounds November 9: Data Linkage Within, Across, and Beyond PCORnet

    November 9, 2018 @ 1:00 pm - 2:00 pm

    Speakers: Thomas W. Carton, PhD, MS Chief Data Officer, Louisiana Public Health Institute PI, REACHnet Keith Marsolo, PhD Instructor Department of Population Health Sciences Duke University School of Medicine Topic: Data Linkage Within, Across, and Beyond PCORnet Date: Friday, November 9, 2018, 1:00-2:00 p.m. ET Meeting Info: To check whether you have the appropriate players installed […]

  • Fri 16

    Grand Rounds November 16: Primary Palliative Care for Emergency Medicine (PRIM-ER)

    November 16, 2018 @ 1:00 pm - 2:00 pm

    Speakers: Corita R. Grudzen, MD, MSHS, FACEP Vice Chair for Research Associate Professor of Emergency Medicine and Population Health Ronald O. Perelman Department of Emergency Medicine NYU School of Medicine Topic: Primary Palliative Care for Emergency Medicine (PRIM-ER) Date: Friday, November 16, 2018, 1:00-2:00 p.m. ET Meeting Info: To check whether you have the appropriate players […]

  • Fri 23

    Grand Rounds November 23rd: No Presentation (Week of Thanksgiving)

    November 23, 2018 @ 1:00 pm - 2:00 pm

    Grand Rounds July 6th: No Presentation (In observance of the Thanksgiving holiday) We hope to see you next week.

  • Fri 30

    Grand Rounds November 30: Validating a Computable Phenotype: Should Results Change a Trial’s Pre-Specified Primary Outcome?

    November 30, 2018 @ 1:00 pm - 2:00 pm

    Speakers: Gregory E Simon MD MPH Senior Investigator, Kaiser Permanente Washington Health Research Institute Susan M. Shortreed, PhD Associate Investigator Biostatistics Unit, Kaiser Permanente Washington Health Research Institute Topic: Validating a Computable Phenotype: Should Results Change a Trial's Pre-Specified Primary Outcome? Date: Friday, November 30, 2018, 1:00-2:00 p.m. ET Meeting Info: To check whether you have […]

  • December 2018

  • Fri 7

    Grand Rounds December 7: Cluster randomized trials in health care delivery systems: lessons from STIC2IT

    December 7, 2018 @ 1:00 pm - 2:00 pm

    Speaker: Niteesh K. Choudhry, MD, PhD Professor, Harvard Medical School Executive Director, Center for Healthcare Delivery Sciences, Brigham and Women’s Hospital Topic: Cluster randomized trials in health care delivery systems: lessons from STIC2IT Date: Friday, December 7, 2018, 1:00-2:00 p.m. ET Meeting Info: To check whether you have the appropriate players installed for UCF (Universal Communications […]

  • Fri 14

    Grand Rounds December 14: Guiding Good Choices for Health (GGC4H): Testing Feasibility and Effectiveness of Universal Parent-Focused Prevention in Three Healthcare Systems

    December 14, 2018 @ 1:00 pm - 2:00 pm

    Speakers: Richard F. Catalano, PhD, MPI GGC4H Co-Founder, Social Development Research Group Professor, School of Social Work University of Washington Margaret Kuklinski, PhD, MPI GGC4H Research Scientist Social Development Research Group School of Social Work University of Washington Stacy Sterling, DrPH, MSW, MPI GGC4H Research Scientist Drug and Alcohol Research Team Behavioral Health Research Initiative […]

  • Fri 21

    Grand Rounds December 21: No Presentation (Week before Christmas Holiday)

    December 21, 2018 @ 1:00 pm - 2:00 pm

    Grand Rounds December 21: No Presentation (In observance of Christmas holiday)  

  • Fri 28

    Grand Rounds December 28: No Presentation (New Year’s Holiday)

    December 28, 2018 @ 1:00 pm - 2:00 pm

    Grand Rounds December 28th: No Presentation (In observance of New Year's holiday) We hope to see you next week.

  • January 2019

  • Fri 4

    Grand Rounds January 4: TRANSFORMing Research for Patients With Heart Failure

    January 4, 2019 @ 1:00 pm - 2:00 pm

    Speakers: Robert J. Mentz, MD Associate Professor of Medicine Duke University School of Medicine Kevin J. Anstrom, PhD Professor of Biostatistics and Bioinformatics Director of Biostatistics, Duke Clinical Research Institute Duke University School of Medicine Eric Eisenstein, DBA Associate Professor in Medicine Duke University School of Medicine Stephen J. Greene, MD Fellow, Division of Cardiology […]

  • Fri 11

    Grand Rounds January 11: Nudge: Text Messaging at Scale in Diverse Health Systems to Support Adherence to Cardiac Medication

    January 11, 2019 @ 1:00 pm - 2:00 pm

    Speakers: Sheana Bull, PhD, MPH Professor, Colorado School of Public Health Director, mHealth Impact Lab Michael Ho, MD, PhD Professor of Medicine, University of Colorado School of Medicine & Staff Cardiologist Eastern Colorado Health Care System (Denver Veteran's Affairs) Topic: Nudge: Text Messaging at Scale in Diverse Health Systems to Support Adherence to Cardiac Medication […]

  • Fri 18

    Grand Rounds January 18: Pragmatic Trials in End-stage Renal Disease (ESRD): HiLo

    January 18, 2019 @ 1:00 pm - 2:00 pm

    Speaker: Myles Wolf, MD, MMSc Charles Johnson, MD Professor of Medicine Chief, Duke Nephrology Duke University School of Medicine Topic: Pragmatic Trials in end-stage renal disease(ESRD): HiLo Date: Friday, January 18, 2019, 1:00-2:00 p.m. ET Meeting Info: To check whether you have the appropriate players installed for UCF (Universal Communications Format) rich media files, go to https://dukemed.webex.com/dukemed/systemdiagnosis.php. […]

  • Fri 25

    Grand Rounds January 25: A Learning Health System Story: Perinatal Outcomes Associated with a Major Change in Gestational Diabetes Screening

    January 25, 2019 @ 1:00 pm - 2:00 pm

    Speakers: Sascha Dublin, MD PhD Senior Investigator Kaiser Permanente Washington Health Research Institute Gaia Pocobelli, PhD Research Associate Kaiser Permanente Washington Health Research Institute Topic: A Learning Health System Story: Perinatal Outcomes Associated with a Major Change in Gestational Diabetes Screening Date: Friday, January 25, 2018, 1:00-2:00 p.m. ET Meeting Info: To check whether you have […]

  • February 2019

  • Fri 1

    Grand Rounds February 1: Promoting Effective Advance Care Planning Communication in the Elderly: The ACP-PEACE Trial

    February 1, 2019 @ 1:00 pm - 2:00 pm

    Speakers: James Tulsky, MD Chair, Department of Psychosocial Oncology and Palliative Care, Dana-Farber Cancer Institute Professor of Medicine, Harvard Medical School Chief, Division of Palliative Medicine, Brigham and Women’s Hospital Angelo Volandes, MD, MPH Associate Professor of Medicine Massachusetts General Hospital, Harvard Medical School Topic: Promoting Effective Advance Care Planning Communication in the Elderly: The […]

  • Fri 8

    Grand Rounds February 8: Paramedic Airway Management in Out-of-Hospital Cardiac Arrest – The Pragmatic Airway Resuscitation Trial (PART)

    February 8, 2019 @ 1:00 pm - 2:00 pm

    Speaker: Henry E. Wang, MD, MS Professor and Vice Chair for Research Department of Emergency Medicine University of Texas Health Science Center at Houston Topic: Paramedic Airway Management in Out-of-Hospital Cardiac Arrest – The Pragmatic Airway Resuscitation Trial (PART) Date: Friday, February 8, 2019, 1:00-2:00 p.m. ET Meeting Info: To check whether you have the appropriate […]

  • Fri 15

    Grand Rounds February 15: Improving Qualification of Investigators: Recommendations from the Clinical Trials Transformation Initiative

    February 15, 2019 @ 1:00 pm - 2:00 pm

    Speakers: Christine M. Hildebrand, PA-C Physician Assistant Sub Investigator Clinical Operations Lead Amici Clinical Research Janette Panhuis Chief Operating Officer, Population Health Research Institute David Braley Research Institute Topic: Improving Qualification of Investigators: Recommendations from the Clinical Trials Transformation Initiative Date: Friday, February 15, 2019, 1:00-2:00 p.m. ET Meeting Info: To check whether you have the […]

  • Fri 22

    Grand Rounds February 22: Going from a Learning Health System to Learning Health Units: Opportunities and Challenges

    February 22, 2019 @ 1:00 pm - 2:00 pm

    Speaker: Adrian F. Hernandez, MD MHS Vice Dean for Clinical Research Duke University School of Medicine Topic: Going from a Learning Health System to Learning Health Units: Opportunities and Challenges Date: Friday, February 22, 2019, 1:00-2:00 p.m. ET Meeting Info: To check whether you have the appropriate players installed for UCF (Universal Communications Format) rich media […]

  • March 2019

  • Fri 1

    Grand Rounds March 1: Approaches to Patient Follow-Up for Clinical Trials: What’s the Right Choice for Your Study ?

    March 1, 2019 @ 1:00 pm - 2:00 pm

    Speaker: Keith Marsolo, PhD Instructor Department of Population Health Sciences Duke University School of Medicine Topic: Approaches to Patient Follow-Up for Clinical Trials: What’s the Right Choice for Your Study? Date: Friday, March 1, 2019, 1:00-2:00 p.m. ET Meeting Info: To check whether you have the appropriate players installed for UCF (Universal Communications Format) rich media […]

  • Fri 8

    Grand Rounds March 8: Dietary Trials in Heart Failure: SODIUM-HF

    March 8, 2019 @ 1:00 pm - 2:00 pm

    Speaker: Justin A. Ezekowitz, MBBCh MSc Professor of Medicine, University of Alberta Co-director, Canadian VIGOUR Centre Topic: Dietary Trials in Heart Failure: SODIUM-HF Date: Friday, March 8, 2019, 1:00-2:00 p.m. ET Meeting Info: To check whether you have the appropriate players installed for UCF (Universal Communications Format) rich media files, go to https://dukemed.webex.com/dukemed/systemdiagnosis.php. To join the online […]

  • Fri 15

    Grand Rounds March 15: Leveraging RWE to Support Regulatory Decisions-An Update on Efforts to Inform Policy

    March 15, 2019 @ 1:00 pm - 2:00 pm

    Speaker: Gregory W. Daniel, PhD, MPH, RPh Deputy Center Director, Duke-Margolis Center for Health Policy Clinical Professor, Fuqua School of Business Duke University Topic: Leveraging RWE to Support Regulatory Decisions-An Update on Efforts to Inform Policy Date: Friday, March 15, 2019, 1:00-2:00 p.m. ET Meeting Info: To check whether you have the appropriate players installed for […]

  • Fri 22

    Grand Rounds March 22: Envisioning Data Liquidity – The Pew Data Interoperability Project

    March 22, 2019 @ 1:00 pm - 2:00 pm

    Speaker: James E. Tcheng, MD Professor of Medicine Professor of Community and Family Medicine (Informatics) Duke University Health System Topic: Envisioning Data Liquidity – The Pew Data Interoperability Project Date: Friday, March 22, 2019, 1:00-2:00 p.m. ET Meeting Info: To check whether you have the appropriate players installed for UCF (Universal Communications Format) rich media files, […]

  • Fri 29

    Grand Rounds March 29: ICD-Pieces: Lessons Learned in an Ongoing Trial

    March 29, 2019 @ 1:00 pm - 2:00 pm

    Speakers: Miguel A. Vazquez, MD Professor of Medicine Clinical Chief Nephrology Division UT Southwestern Medical Center George (Holt) Oliver, MD, PhD Vice President Clinical Informatics Parkland Center for Clinical Innovation Topic: ICD-Pieces: Lessons Learned in an Ongoing Trial Date: Friday, March 29, 2019, 1:00-2:00 p.m. ET Meeting Info: To check whether you have the appropriate players […]

  • April 2019

  • Fri 5

    Grand Rounds April 5: The ENGAGES Pragmatic Trial and the Power of Negative Thinking

    April 5, 2019 @ 1:00 pm - 2:00 pm

    Speaker: Michael S. Avidan, MBBCh, FCA SA Dr. Seymour and Rose T. Brown Professor of Anesthesiology Chief, Division of Clinical and Translational Research Washington University in St. Louis, School of Medicine Department of Anesthesiology Topic: The ENGAGES Pragmatic Trial and the Power of Negative Thinking Date: Friday, April 5, 2019, 1:00-2:00 p.m. ET Meeting Info: To […]

  • Fri 12

    Grand Rounds April 12: Development of Harmonized Outcome Measures for Use in Research and Clinical Practice

    April 12, 2019 @ 1:00 pm - 2:00 pm

    Speakers: Richard Gliklich, MD CEO, OM1, Inc. Michelle B. Leavy, MPH Head, Healthcare Research & Policy OM1, Inc. Elise Berliner, PhD Director, Technology Assessment Program Center for Evidence and Practice Improvement (CEPI) Agency for Healthcare Research and Quality (AHRQ) Topic: Development of Harmonized Outcome Measures for Use in Research and Clinical Practice Date: Friday, April 12, […]

  • Fri 19

    Grand Rounds April 19: The Trauma Survivors Outcomes & Support (TSOS) Pragmatic Trial: Revisiting Effectiveness & Implementation Aims

    April 19, 2019 @ 1:00 pm - 2:00 pm

    Speaker: Doug Zatzick, MD Professor of Psychiatry Harborview Medical Center University of Washington School of Medicine Topic: The Trauma Survivors Outcomes & Support (TSOS) Pragmatic Trial : Revisiting Effectiveness & Implementation Aims Date: Friday, April 19, 2019, 1:00-2:00 p.m. ET Meeting Info: To check whether you have the appropriate players installed for UCF (Universal Communications Format) […]

  • Fri 26

    Grand Rounds April 26: The VERITAS Trial: Virtual Exercise Rehabilitation at the Intersection of Evidence, Implementation, and Policy

    April 26, 2019 @ 1:00 pm - 2:00 pm

    Speaker: Janet Prvu Bettger, ScD, FAHA Associate Professor Duke Department of Orthopaedic Surgery Duke Clinical Research Institute Topic: The VERITAS Trial: Virtual Exercise Rehabilitation at the Intersection of Evidence, Implementation, and Policy Date: Friday, April 26, 2019, 1:00-2:00 p.m. ET Meeting Info: To check whether you have the appropriate players installed for UCF (Universal Communications Format) […]

  • May 2019

  • Thu 2

    NIH Workshop: Design & Analysis of Embedded Pragmatic Clinical Trials

    May 2, 2019 @ 8:00 am - 4:30 pm

    The NIH Health Care Systems Research Collaboratory is hosting a one-day workshop on the Design & Analysis of Embedded Pragmatic Clinical Trials (ePCTs) on May 2, 2019, in the Lister Hill Auditorium on the NIH Campus. The workshop will include a series of moderated discussions that focus on issues of measuring trial outcomes from available […]

  • Fri 3

    Grand Rounds May 3: Effects of Financial Bonus Sizes, Loss Aversion, and Increased Social Pressure on Physician Pay-for-Performance: A Randomized Trial and Cohort Study

    May 3, 2019 @ 1:00 pm - 2:00 pm

    Speaker: Amol S. Navathe, MD, PhD Assistant Professor of Medicine and Health Policy, University of Pennsylvania Topic: Effects of Financial Bonus Sizes, Loss Aversion, and Increased Social Pressure on Physician Pay-for-Performance: A Randomized Trial and Cohort Study Date: Friday, May 3, 2019, 1:00-2:00 p.m. ET Meeting Info: To check whether you have the appropriate players installed […]

  • Fri 10

    Grand Rounds May 10: Treating Data as an Asset: Data Entrepreneurship in the Service of Patients

    May 10, 2019 @ 1:00 pm - 2:00 pm

    Speaker: Eric D Perakslis MS PhD Rubenstein Fellow, Duke University Lecturer, Department of Biomedical Informatics Harvard Medical School Topic: Treating Data as an Asset: Data Entrepreneurship in the Service of Patients Date: Friday, May 10, 2019, 1:00-2:00 p.m. ET Meeting Info: To check whether you have the appropriate players installed for UCF (Universal Communications Format) rich […]

  • Fri 17

    Grand Rounds May 17: The VITamin D and OmegA-3 TriaL (VITAL): Design and Results of a Large Pragmatic Trial

    May 17, 2019 @ 1:00 pm - 2:00 pm

    Speaker: JoAnn E. Manson, MD, DrPH Chief, Division of Preventive Medicine, Brigham and Women's Hospital Professor of Medicine and the Michael and Lee Bell Professor of Women's Health, Harvard Medical School Professor, Department of Epidemiology, Harvard T.H. Chan School of Public Health Topic: The VITamin D and OmegA-3 TriaL (VITAL):  Design and Results of a […]

  • Fri 24

    Grand Rounds May 24: No Presentation (Memorial Day Holiday)

    May 24, 2019 @ 1:00 pm - 2:00 pm
  • Fri 31

    Grand Rounds May 31: Adapting Clinical Trial Design to Meet the Needs of Learning Health Systems

    May 31, 2019 @ 1:00 pm - 2:00 pm

    Speaker: Harriette G.C. Van Spall, MD, MPH, FRCPC Associate Professor of Medicine Department of Medicine, Division of Cardiology Department of Health Research Methods, Evidence, and Impact McMaster University Population Health Research Institute Topic: Adapting Clinical Trial Design to Meet the Needs of Learning Health Systems Date: Friday, May 31, 2019, 1:00-2:00 p.m. ET Meeting Info: To […]

  • June 2019

  • Fri 7

    Grand Rounds June 7: In Dreams Begin Responsibilities: Data Science as a Service—Using AI to Risk Stratify a Medicare Population and Build a Culture

    June 7, 2019 @ 1:00 pm - 2:00 pm

    Speaker: Erich S. Huang, MD, PhD Co-Director, Duke Forge Departments of Biostatistics & Bioinformatics and Surgery Duke University School of Medicine Topic: In Dreams Begin Responsibilities: Data Science as a Service—using AI to Risk Stratify a Medicare Population and Build a Culture Date: Friday, June 7, 2019, 1:00-2:00 p.m. ET Meeting Info: To check whether you have the […]

  • Fri 14

    Grand Rounds June 14: Good Clinical Practice Guidance and Pragmatic Trials: Balancing the Best of Both Worlds in the Learning Health System

    June 14, 2019 @ 1:00 pm - 2:00 pm

    Speaker: Robert J. Mentz, MD, FACC, FAHA, FHFSA Associate Professor Director, Duke Cooperative Cardiovascular Society Associate Program Director, Duke Cardiovascular Disease Fellowship Duke University Medical Center and Duke Clinical Research Institute Topic: Good Clinical Practice Guidance and Pragmatic Trials: Balancing the Best of Both Worlds in the Learning Health System Date: Friday, June 14, 2019, 1:00-2:00 […]

  • Fri 21

    Grand Rounds June 21: A Polypill Strategy for Cardiovascular Prevention in Underserved Populations – Can We Bridge the Gap?

    June 21, 2019 @ 1:00 pm - 2:00 pm

    Speakers: Daniel Muñoz, MD, MPA Assistant Professor of Medicine Division of Cardiology Vanderbilt University Medical Center Thomas J. Wang, MD Professor of Medicine Gottlieb C. Friesinger II Chair in Cardiovascular Medicine Director, Division of Cardiovascular Medicine Vanderbilt University Medical Center Physician-in-Chief, Vanderbilt Heart & Vascular Institute Topic: A Polypill Strategy for Cardiovascular Prevention in Underserved […]

  • Fri 28

    Grand Rounds June 28: Moving Beyond Return of Research Results to Return of Value

    June 28, 2019 @ 1:00 pm - 2:00 pm

    Speaker: Consuelo H. Wilkins, MD, MSCI Vice President for Health Equity, Vanderbilt University Medical Center Executive Director, Meharry-Vanderbilt Alliance Topic: Moving Beyond Return of Research Results to Return of Value Date: Friday, June 28, 2019, 1:00-2:00 p.m. ET Meeting Info: To check whether you have the appropriate players installed for UCF (Universal Communications Format) rich media […]

  • July 2019

  • Fri 5

    Grand Rounds July 5: No Presentation (Independence Day Holiday)

    July 5, 2019 @ 1:00 pm - 2:00 pm
  • Fri 12

    Grand Rounds July 12: medRxiv: A Paradigm Shift in Disseminating Clinical and Public Health Research

    July 12, 2019 @ 1:00 pm - 2:00 pm

    Speakers: Harlan M. Krumholz, MD, SM Harold H. Hines, Jr. Professor of Medicine and Public Health Yale University Joseph S. Ross, MD, MHS Associate Professor of Medicine and Public Health Yale University Topic: medRxiv: A Paradigm Shift in Disseminating Clinical and Public Health Research Date: Friday, July 12, 2019, 1:00-2:00 p.m. ET Meeting Info: To […]

  • Fri 19

    Grand Rounds July 19: Misinformation as a Source of Complication for Clinical Trials

    July 19, 2019 @ 1:00 pm - 2:00 pm

    Speaker: Brian Southwell, PhD Senior Director, Science in the Public Sphere, RTI International Duke-RTI Scholar, Duke Forge, Duke University Topic: Misinformation as a Source of Complication for Clinical Trials Date: Friday, July 19, 2019, 1:00-2:00 p.m. ET Meeting Info: To check whether you have the appropriate players installed for UCF (Universal Communications Format) rich media files, go to […]

  • Fri 26

    Grand Rounds July 26: Digital in Trials: Improving Participation and Enabling Novel Endpoints

    July 26, 2019 @ 1:00 pm - 2:00 pm

    Speaker: Craig H. Lipset Former Head of Clinical Innovation Pfizer Topic: Digital in Trials: Improving Participation and Enabling Novel Endpoints Date: Friday, July 26, 2019, 1:00-2:00 p.m. ET Meeting Info: To check whether you have the appropriate players installed for UCF (Universal Communications Format) rich media files, go to https://dukemed.webex.com/dukemed/systemdiagnosis.php. To join the online meeting: […]

  • August 2019

  • Fri 2

    Grand Rounds August 2, 2019: AI and the Future of Psychiatry

    August 2, 2019 @ 1:00 pm - 2:00 pm

    Speaker: Murali Doraiswamy Professor of Psychiatry and Behavioral Sciences Duke School of Medicine Topic: AI and the Future of Psychiatry Date: Friday, August 2, 2019, 1:00-2:00 p.m. ET Meeting Info: To check whether you have the appropriate players installed for UCF (Universal Communications Format) rich media files, go to https://dukemed.webex.com/dukemed/systemdiagnosis.php. To join the online meeting: […]

  • Fri 9

    Grand Rounds August 9: Open Science: Are we there yet?

    August 9, 2019 @ 1:00 pm - 2:00 pm

    Speaker: Adrian Hernandez, MD Professor of Medicine Vice Dean for Clinical Research Duke University, School of Medicine Topic: Open Science: Are we there yet? Date: Friday, August 9, 2019, 1:00-2:00 p.m. ET Meeting Info: To check whether you have the appropriate players installed for UCF (Universal Communications Format) rich media files, go to https://dukemed.webex.com/dukemed/systemdiagnosis.php. To […]

  • Fri 16

    Grand Rounds August 16: Introducing the Digital Medicine Society (DiMe)

    August 16, 2019 @ 1:00 pm - 2:00 pm

    Speakers: Andy Coravos CEO, Elektra Labs Fellow, Harvard-MIT Center for Regulatory Science Co-founder, Digital Medicine Society (DiMe) Jen Goldsack Interim Executive Director, DiMe Portfolio, Strategy & Ops, HealthMode Topic: Introducing the Digital Medicine Society (DiMe) Date: Friday, August 16, 2019, 1:00-2:00 p.m. ET Meeting Info: To check whether you have the appropriate players installed for […]

  • Fri 23

    Grand Rounds August 23: Oh yes, we have tons of patients who can do this study!

    August 23, 2019 @ 1:00 pm - 2:00 pm

    Speaker: Vanita R. Aroda, MD Director of Diabetes Clinical Research Brigham & Women’s Hospital Harvard Medical School Topic: Oh yes, we have tons of patients who can do this study! Date: Friday, August 23, 2019, 1:00-2:00 p.m. ET Meeting Info: To check whether you have the appropriate players installed for UCF (Universal Communications Format) rich […]

  • Fri 30

    Grand Rounds August 30: No Presentation (Labor Day Holiday)

    August 30, 2019 @ 1:00 pm - 2:00 pm
  • September 2019

  • Fri 6

    Grand Rounds September 6: Transforming Medical Evidence Generation with Technology-Enabled Trials

    September 6, 2019 @ 1:00 pm - 2:00 pm

    Speaker: Matthew T. Roe, MD, MHS Senior Investigator, Professor of Medicine Duke Clinical Research Institute Topic: Transforming Medical Evidence Generation with Technology-Enabled Trials Date: Friday, September 6, 2019, 1:00-2:00 p.m. […]

  • Fri 13

    Grand Rounds September 13: ADAPTABLE Recruitment and Follow-up: Health Plan Research Network Engagement

    September 13, 2019 @ 1:00 pm - 2:00 pm

    Speaker: Kevin Haynes, PharmD, MSCE Principal Scientist HealthCore, Inc. Topic: ADAPTABLE Recruitment and Follow-up: Health Plan Research Network Engagement Date: Friday, September 13, 2019, 1:00-2:00 p.m. ET Meeting Info: To […]

  • Fri 20

    Grand Rounds September 20: Designing & Testing the Future of Home-based Cervical Cancer Screening: Results from a Collaborative Academic-Embedded Delivery System Pragmatic Randomized Trial

    September 20, 2019 @ 1:00 pm - 2:00 pm

    Speakers: Rachel L. Winer, PhD University of Washington School of Public Health Department of Epidemiology Diana S.M. Buist, PhD, MPH Kaiser Permanente Washington Health Research Institute Topic: Designing & testing […]

  • Fri 27

    Grand Rounds September 27: Preparing for Clinical Trial Data Sharing and Re-use: The New Reality for Researchers

    September 27, 2019 @ 1:00 pm - 2:00 pm

    Speakers: Rebecca Li, PhD Executive Director, Vivli Co-Director of Research Ethics, Harvard Center for Bioethics Harvard Medical School Frank W. Rockhold, PhD Professor of Biostatistics and Bioinformatics Duke Clinical Research […]

  • October 2019

  • Fri 4

    Grand Rounds October 4: Ascertaining Death and Hospitalization Endpoints: The TRANSFORM-HF Experience

    October 4, 2019 @ 1:00 pm - 2:00 pm

    Speakers: Eric L. Eisenstein, DBA Associate Professor in Medicine Duke University School of Medicine Kevin J. Anstrom, PhD Professor of Biostatistics and Bioinformatics Director of Biostatistics, Duke Clinical Research Institute […]

  • Fri 11

    Grand Rounds October 11: Objecting to Experiments that Compare Two Unobjectionable Policies or Treatments: Implications for Comparative Effectiveness and Other Pragmatic Clinical Trials

    October 11, 2019 @ 1:00 pm - 2:00 pm

    Speaker: Michelle N. Meyer, PhD, JD Assistant Professor & Associate Director, Research Ethics Center for Translational Bioethics & Health Care Policy Faculty Co-Director, Behavioral Insights Team Steele Institute for Health […]

  • Fri 18

    Grand Rounds October 18: Playing with FHIR–Innovative Use Cases for the New REDCap EHR Integration Module

    October 18, 2019 @ 1:00 pm - 2:00 pm

    Speaker: Paul A. Harris, PhD Director, Professor of Biomedical Informatics Vanderbilt University Medical Center Topic: Playing with FHIR–Innovative Use Cases for the New REDCap EHR Integration Module Date: Friday, October 18, 2019, 1:00-2:00 p.m. ET Meeting Info: To check whether you have the appropriate players installed for UCF (Universal Communications Format) rich media files, go […]

  • Fri 25

    Grand Rounds October 25: Real-World Evidence for Drug Effectiveness Evaluation: Addressing the Credibility Gap

    October 25, 2019 @ 1:00 pm - 2:00 pm

    Speaker: Richard Willke, PhD Chief Science Officer, ISPOR Topic: Real-World Evidence for Drug Effectiveness Evaluation: Addressing the Credibility Gap Date: Friday, October 25, 2019, 1:00-2:00 p.m. ET Meeting Info: To check whether you have the appropriate players installed for UCF (Universal Communications Format) rich media files, go to https://dukemed.webex.com/dukemed/systemdiagnosis.php. To join the online meeting: Go […]

  • November 2019

  • Fri 1

    Grand Rounds November 1: NIH Collaboratory: Looking Back and Looking Forward

    November 1, 2019 @ 1:00 pm - 2:00 pm

    Speakers: Adrian F. Hernandez, MD, MHS Professor of Medicine Vice Dean for Clinical Research Duke University, School of Medicine Lesley H. Curtis, PhD Chair and Professor Department of Population Health Sciences Duke University School of Medicine Interim Executive Director, Duke Clinical Research Institute Kevin Weinfurt, PhD Professor and Vice Chair of Research Department of Population […]

  • Fri 8

    Grand Rounds November 8: Lumbar Imaging with Reporting of Epidemiology: Initial Results and Some Lessons Learned

    November 8, 2019 @ 1:00 pm - 2:00 pm

    Speakers: Jeffrey (Jerry) G. Jarvik MD MPH Professor, Radiology, Neurological Surgery and Health Services Adjunct Professor, Pharmacy and Orthopedics & Sports Medicine University of Washington Patrick Heagerty, PhD Professor and Chair Department of Biostatistics University of Washington Topic: Lumbar Imaging with Reporting of Epidemiology: Initial Results and Some Lessons Learned Date: Friday, November 8, 2019, […]

  • Fri 15

    Grand Rounds November 15: PCORnet: Health Plan Research Network Data Linkage and Patient Engagement with Patient-Powered Research Networks

    November 15, 2019 @ 1:00 pm - 2:00 pm

    Speaker: Kevin Haynes, PharmD, MSCE Principal Scientist HealthCore Topic: PCORnet: Health Plan Research Network Data Linkage and Patient Engagement with Patient-Powered Research Networks Date: Friday, November 15, 2019, 1:00-2:00 p.m. ET Meeting Info: To check whether you have the appropriate players installed for UCF (Universal Communications Format) rich media files, go to https://dukemed.webex.com/dukemed/systemdiagnosis.php. To join […]

  • Thu 21

    IMPACT Collaboratory: Are You Ready for a Pragmatic Trial? The RAPT Model and Implementation Considerations

    November 21, 2019 @ 12:00 pm - 1:00 pm

    Speakers: Rosa Baier, MPH Associate Director, Center for Long-Term Care Quality & Innovation Associate Professor, Health Sciences, Policy & Practice Brown University School of Medicine Eric Jutkowitz, PhD Assistant Professor Brown University School of Public Health Laura Gitlin, PhD, FGSA, FAAN Dean, Distinguished Professor, Drexel University Adjunt Professor, Johns Hopkins University Read more about the […]

  • Fri 22

    Grand Rounds November 22: It’s Time to Learn From Patients Like Mine

    November 22, 2019 @ 1:00 pm - 2:00 pm

    Speaker: Nigam H Shah, MBBS, PhD Associate Professor of Medicine Stanford University Topic: It's Time to Learn From Patients Like Mine Date: Friday, November 22, 2019, 1:00-2:00 p.m. ET Meeting Info: To check whether you have the appropriate players installed for UCF (Universal Communications Format) rich media files, go to https://dukemed.webex.com/dukemed/systemdiagnosis.php. To join the online […]

  • Fri 29

    Grand Rounds November 29: No Presentation (Thanksgiving Holiday)

    November 29, 2019 @ 1:00 pm - 2:00 pm
  • December 2019

  • Fri 6

    Grand Rounds December 6: Millions More People, Stronger Collaborations: The New and Improved NIH Collaboratory Distributed Research Network

    December 6, 2019 @ 1:00 pm - 2:00 pm

    Speakers: Richard Platt, MD, MS Professor and Chair Harvard Medical School Department of Population Medicine Kevin Haynes, PharmD, MSCE Principal Scientist HealthCore Denise Boudreau, PhD Senior Scientific Investigator Kaiser Permanente Washington Health Research Institute Jerry H. Gurwitz, MD Professor of Medicine, Family Medicine and Community Health, and Population & Quantitative Health Sciences University of Massachusetts […]

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