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Living Textbook of
Pragmatic Clinical Trials

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Rethinking Clinical Trials

A Living Textbook of Pragmatic Clinical Trials

  • Design
    • What is a Pragmatic Clinical Trial?
    • Decentralized Pragmatic Clinical Trials
    • Developing a Compelling Grant Application
    • Experimental Designs and Randomization Schemes
    • Endpoints and Outcomes
    • Analysis Plan
    • Using Electronic Health Record Data
    • Building Partnerships and Teams to Ensure a Successful Trial
    • Intervention Delivery and Complexity
    • Patient Engagement
  • Data, Tools & Conduct
    • Assessing Feasibility
    • Acquiring Real-World Data
    • Assessing Fitness-for-Use of Real-World Data
    • Study Startup
    • Participant Recruitment
    • Monitoring Intervention Fidelity and Adaptations
    • Patient-Reported Outcomes
    • Clinical Decision Support
    • Electronic Health Records–Based Phenotyping
    • Navigating the Unknown
  • Dissemination & Implementation
    • Data Sharing and Embedded Research
    • Dissemination Approaches for Different Audiences
    • Implementation
    • End-of-Trial Decision-Making
  • Ethics & Regulatory
    • Privacy Considerations
    • Identifying Those Engaged in Research
    • Collateral Findings
    • Consent, Disclosure, and Non-Disclosure
    • Data and Safety Monitoring
    • Ethical Considerations of Data Sharing in Pragmatic Clinical Trials
    • Ethics for AI and ML
    • IRB Responsibilities and Procedures
70 events found.

Events

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  • December 2016

  • Fri 16

    Comparison of Different Approaches for Notification and Authorization in Pragmatic Clinical Research Evaluating Commonly Used Medical Practices

    December 16, 2016 @ 1:00 pm - 2:00 pm

    Presenter: Weinfurt, Kevin Slides: Slides Video: Grand-Rounds-12-16-16

  • January 2017

  • Fri 6

    21st Century Cures Overview and Implications

    January 6, 2017 @ 1:00 pm - 2:00 pm

    Presenter: Daniel, Gregory Slides: Slides Video: Grand-Rounds-01-06-17

  • Fri 13

    What’s Next: People-Powered Knowledge Generation from Digital Health Data

    January 13, 2017 @ 1:00 pm - 2:00 pm

    Presenter: Krumholz, Harlan Slides: Slides Video: Grand-Rounds-01-13-17

  • Fri 20

    What “High Utilizers” Can Tell Us About Population Health

    January 20, 2017 @ 1:00 pm - 2:00 pm

    Presenter: Labby, David Slides: Slides Video: Grand-Rounds-01-20-17

  • Fri 27

    Connecting the Dots: Behavioral Economics and a Cluster Randomized Trial

    January 27, 2017 @ 1:00 pm - 2:00 pm

    Presenter: Hernandez, Adrian Slides: Slides Video: Grand-Rounds-01-27-17

  • February 2017

  • Fri 3

    A Tentative Introduction to the Revised Common Rule for the Protection of Human Subjects

    February 3, 2017 @ 1:00 pm - 2:00 pm

    Presenter: Sugarman, Jeremy Slides: Slides Audio: Grand-Rounds-02-03-17

  • Fri 10

    INVESTED Vanguard Year: What Did We Learn About SMART IRB?

    February 10, 2017 @ 1:00 pm - 2:00 pm

    Presenter: Cobb, Nichelle Slides: Slides Video: Grand-Rounds-02-10-17

  • Fri 17

    Healthier Together: Collaborative Networks of Patients, Clinicians and Researchers Creating Learning Health Systems

    February 17, 2017 @ 1:00 pm - 2:00 pm

    Presenter: Margolis, Peter Slides: Slides Video: Grand-Rounds-02-17-17

  • Fri 24

    Where Are We On Our Path to Digital Healthcare (And Why Is It So Hard?)

    February 24, 2017 @ 1:00 pm - 2:00 pm

    Presenter: Wachter, Robert Slides: Slides Video: Grand-Rounds-02-24-17

  • March 2017

  • Fri 3

    Showcasing Innovative Operational and Recruitment Approaches in the ADAPTABLE Trial

    March 3, 2017 @ 1:00 pm - 2:00 pm

    Presenter: Roe, Matthew Slides: Slides Video: Grand-Rounds-03-03-17

  • Fri 10

    Implementing PROVEN

    March 10, 2017 @ 1:00 pm - 2:00 pm

    Presenter: Mor, Vincent Slides: Slides Video: Grand-Rounds-03-10-17

  • Fri 17

    Establishing the National Evaluation System for Health Technology (NEST) Coordinating Center

    March 17, 2017 @ 1:00 pm - 2:00 pm

    Presenter: Murray, Bill Slides: SlidesVideo: Grand-Rounds-03-17-17

  • Fri 24

    Patient-Reported Outcomes: A Critical Insight into the Impact of Therapy

    March 24, 2017 @ 1:00 pm - 2:00 pm

    Presenter: Spertus, John Slides: Slides Video: Grand-Rounds-03-24-17

  • Fri 31

    FDA and Pragmatic Trials

    March 31, 2017 @ 1:00 pm - 2:00 pm

    Presenter: Califf, Robert Slides: Slides Video: Grand-Rounds-03-31-17

  • April 2017

  • Fri 7

    Healthy Hearts Northwest: A 2×2 Randomized Factorial Trial to Build Quality Improvement Capacity in Primary Care

    April 7, 2017 @ 1:00 pm - 2:00 pm

    Presenter: Parchman, Michael Slides: Slides Video: Grand-Rounds-04-07-17

  • Thu 13

    Hardwiring Patient Engagement to Deliver Better Health

    April 13, 2017 @ 9:00 am - 1:00 pm

    Speakers: Multiple Speakers; Produced by NEJM Catalyst and hosted by Kaiser Permanente Southern California Topic: Hardwiring Patient Engagement to Deliver Better Health Date: Thursday, April 13, 2017, 9:00 a.m-1:00 p.m. ET Meeting Info: In this free, live web event from NEJM Catalyst, you’ll learn how to design provider care teams, patient networks, and patient-provider interactions […]

  • Fri 14

    Toward National Trauma Care Practice Change for PTSD & Comorbidity: Lessons Learned from the TSOS Pragmatic Trial

    April 14, 2017 @ 1:00 pm - 2:00 pm

    Presenter: Jurkovich, Gregory Slides: Slides Video: Grand-Rounds-04-14-17

  • Fri 21

    Testing New Models of Research Funding: One Brave Idea

    April 21, 2017 @ 1:00 pm - 2:00 pm

    Presenter: MacRae, Calum Slides: Slides Video: Grand-Rounds-04-21-17

  • Fri 28

    Perspective on the Boundary Between Quality Improvement Studies and Research: Patients, QI Leaders, IRB Leaders

    April 28, 2017 @ 1:00 pm - 2:00 pm

    Presenters: Sherrie Kaplan, Susan Huang Slides: Slides Video: Grand-Rounds-04-28-17

  • May 2017

  • Fri 5

    Grand Rounds: May 5: SUPPORT, BOOST II, and COT Trials: You Must Understand Usual Care to Safeguard Patients and Make Firm Conclusions (Charles Natanson, MD)

    May 5, 2017 @ 1:00 pm - 2:00 pm
    https://dukemed.webex.com/dukemed/j.php?MTID=m4c6e3e4827442a92338a5649cee613e6

    ​Speaker: Charles Natanson, MD Senior Investigator National Institutes of Health Slide: Slides Video: Grand-Rounds-5-5-17 Topic:SUPPORT, BOOST II, and COT Trials: You Must Understand Usual Care to Safeguard Patients and Make Firm Conclusions Date: Friday, May 5, 2017, 1:00-2:00 p.m. ET Meeting Info: To check whether you have the appropriate players installed for UCF (Universal Communications Format) rich […]

  • Fri 12

    Grand Rounds: May 12: Pragmatic Clinical Trials & Learning Health Care Systems: Strategies to Facilitate Implementation of Results into Clinical Care (Eric Larson, MD, MPH; Leah Tuzzio, MPH)

    May 12, 2017 @ 1:00 pm - 2:00 pm
    https://dukemed.webex.com/dukemed/j.php?MTID=m4c6e3e4827442a92338a5649cee613e6

    ​Speakers: Eric Larson, MD, MPH VP of Research and Health Care Innovation Executive Director and Senior Investigator Kaiser Permanente Washington Health Research Institute Leah Tuzzio, MPH Research Associate Kaiser Permanente Washington Health Research Institute Topic:Pragmatic Clinical Trials & Learning Health Care Systems: Strategies to Facilitate Implementation of Results into Clinical Care Date: Friday, May 12, 2017, 1:00-2:00 […]

  • Fri 12

    Grand Rounds: May 12: Pragmatic Clinical Trials & Learning Health Care Systems: Strategies to Facilitate Implementation of Results into Clinical Care (Eric Larson, MD, MPH; Leah Tuzzio, MPH)

    May 12, 2017 @ 1:00 pm - 2:00 pm
    https://dukemed.webex.com/dukemed/j.php?MTID=m4c6e3e4827442a92338a5649cee613e6

    ​Speakers: Eric Larson, MD, MPH VP of Research and Health Care Innovation Executive Director and Senior Investigator Kaiser Permanente Washington Health Research Institute Leah Tuzzio, MPH Research Associate Kaiser Permanente Washington Health Research Institute Topic:Pragmatic Clinical Trials & Learning Health Care Systems: Strategies to Facilitate Implementation of Results into Clinical Care Date: Friday, May 12, 2017, 1:00-2:00 […]

  • Fri 19

    Grand Rounds: May 19: Collaborations and Synergies: CTSA Program/Trial Innovation Network and PCORnet (Danny Benjamin, MD, PhD; Adrian Hernandez, MD, MHS; Monica Shah, MD)

    May 19, 2017 @ 1:00 pm - 2:00 pm
    https://dukemed.webex.com/dukemed/j.php?MTID=m4c6e3e4827442a92338a5649cee613e6

    ​Speakers: Danny Benjamin, MD, PhD Kiser-Arena Distinguished Professor of Pediatrics Duke University Chair, Pediatric Trials Network Associate Director, Duke Clinical Research Institute Adrian F. Hernandez, MD, MHS, FAHA Professor of Medicine Duke University Medical Center Director, Health Services & Outcomes Research Faculty Associate Director Duke Clinical Research Institute Monica Shah, MD Director, Trial Innovation Network […]

  • Fri 19

    May 19 Grand Rounds: Collaborations and Synergies: CTSA Program/Trial Innovation Network and PCORnet (Danny Benjamin, MD, PhD; Adrian Hernandez, MD, MHS; Monica Shah, MD)

    Featured May 19, 2017 @ 1:00 pm - 2:00 pm
    https://dukemed.webex.com/dukemed/j.php?MTID=m4c6e3e4827442a92338a5649cee613e6

    ​Speakers: Danny Benjamin, MD, PhD Kiser-Arena Distinguished Professor of Pediatrics Duke University Chair, Pediatric Trials Network Associate Director, Duke Clinical Research Institute Adrian F. Hernandez, MD, MHS, FAHA Professor of Medicine Duke University Medical Center Director, Health Services & Outcomes Research Faculty Associate Director Duke Clinical Research Institute Monica Shah, MD Director, Trial Innovation Network […]

  • Wed 24

    Pragmatic Clinical Trials – Unique Opportunities for Disseminating, Implementing & Sustaining Evidence-Based Practices into Clinical Care

    May 24, 2017 @ 8:00 am - 4:30 pm

    ​Date: Wednesday, May 24, 2017 8am to 4:30pm ET Meeting Info: This one-day workshop will explore challenges and strategies for the dissemination, implementation, and sustainability of pragmatic clinical trial findings. Participants are invited to submit questions or specific areas of concern during the registration process. NIH will attempt to address as many questions/areas of concern as possible during […]

  • Wed 24

    Pragmatic Clinical Trials – Unique Opportunities for Disseminating, Implementing & Sustaining Evidence-Based Practices into Clinical Care

    May 24, 2017 @ 8:00 am - 4:30 pm

    ​Date: Wednesday, May 24, 2017 8am to 4:30pm ET Meeting Info: This one-day workshop will explore challenges and strategies for the dissemination, implementation, and sustainability of pragmatic clinical trial findings. Participants are invited to submit questions or specific areas of concern during the registration process. NIH will attempt to address as many questions/areas of concern as possible during […]

  • June 2017

  • Fri 2

    Grand Rounds: June 2: PCORnet Health Plan Research Networks (HPRN): Data Linkage Activities to Facilitate Longitudinal Pragmatic and Observational CER (Kevin Haynes, PharmD; Vinit Nair, BPharm, MS, RpH)

    June 2, 2017 @ 1:00 pm - 2:00 pm
    https://dukemed.webex.com/dukemed/j.php?MTID=m4c6e3e4827442a92338a5649cee613e6

    ​Speakers: Kevin Haynes, PharmD MSCE Director of Clinical Epidemiology, HealthCore, Inc. Vinit P Nair, BPharm, MS, RpH Director & Practice Lead Government Research & Academic Partnerships, HUMANA Inc. Topic: PCORnet Health Plan Research Networks (HPRN): Data Linkage Activities to Facilitate Longitudinal Pragmatic and Observational CER Date: Friday, June 2, 2017, 1:00-2:00 p.m. ET Meeting Info: To check whether you […]

  • Fri 2

    June 2 Grand Rounds: PCORnet Health Plan Research Networks (HPRN): Data Linkage Activities to Facilitate Longitudinal Pragmatic and Observational CER (Kevin Haynes, PharmD; Vinit Nair, BPharm, MS, RpH)

    Featured June 2, 2017 @ 1:00 pm - 2:00 pm
    https://dukemed.webex.com/dukemed/j.php?MTID=m4c6e3e4827442a92338a5649cee613e6

    ​Speakers: Kevin Haynes, PharmD MSCE Director of Clinical Epidemiology, HealthCore, Inc. Vinit P Nair, BPharm, MS, RpH Director & Practice Lead Government Research & Academic Partnerships, HUMANA Inc. Topic: PCORnet Health Plan Research Networks (HPRN): Data Linkage Activities to Facilitate Longitudinal Pragmatic and Observational CER Date: Friday, June 2, 2017, 1:00-2:00 p.m. ET Meeting Info: To check whether you […]

  • Mon 5

    Grand Rounds: May 5: SUPPORT, BOOST II, and COT Trials: You Must Understand Usual Care to Safeguard Patients and Make Firm Conclusions (Charles Natanson, MD)

    June 5, 2017 @ 1:00 pm - 2:00 pm
    https://dukemed.webex.com/dukemed/j.php?MTID=m4c6e3e4827442a92338a5649cee613e6

    ​Speaker: Charles Natanson, MD Senior Investigator National Institutes of Health Topic:SUPPORT, BOOST II, and COT Trials: You Must Understand Usual Care to Safeguard Patients and Make Firm Conclusions Date: Friday, May 5, 2017, 1:00-2:00 p.m. ET Meeting Info: To check whether you have the appropriate players installed for UCF (Universal Communications Format) rich media files, go tohttps://dukemed.webex.com/dukemed/systemdiagnosis.php. […]

  • Fri 30

    Grand Rounds: June 30: The Yale Open Data Access (YODA) Project: Lessons Learned in Data Sharing (Joseph S. Ross, MD, MHS)

    June 30, 2017 @ 1:00 pm - 2:00 pm

    ​Speaker: Joseph S. Ross, MD, MHS Associate Professor of Medicine, General Medicine, and Public Health, Health Policy and Management Yale University School of Medicine Topic: The Yale Open Data Access (YODA) Project: Lessons Learned in Data Sharing Date: Friday, June 30, 2017, 1:00-2:00 p.m. ET Meeting Info: To check whether you have the appropriate players installed for UCF […]

  • Fri 30

    June 30 Grand Rounds: The Yale Open Data Access (YODA) Project: Lessons Learned in Data Sharing (Joseph S. Ross, MD, MHS)

    Featured June 30, 2017 @ 1:00 pm - 2:00 pm

    ​Speaker: Joseph S. Ross, MD, MHS Associate Professor of Medicine, General Medicine, and Public Health, Health Policy and Management Yale University School of Medicine Topic: The Yale Open Data Access (YODA) Project: Lessons Learned in Data Sharing Date: Friday, June 30, 2017, 1:00-2:00 p.m. ET Meeting Info: To check whether you have the appropriate players installed for UCF […]

  • July 2017

  • Fri 7

    Grand Rounds: July 7: Ethics and the Precision Medicine Initiative: Reflections from Working on the CentralPMI IRB (Nancy Kass, ScD)

    July 7, 2017 @ 1:00 pm - 2:00 pm

    ​Speaker: Nancy Kass, ScD Phoebe R. Berman Professor of Bioethics and Public Health Johns Hopkins Berman Institute of Bioethics Johns Hopkins Bloomberg School of Public Health Topic: Ethics and the Precision Medicine Initiative: Reflections from Working on the CentralPMI IRB Date: Friday, July 7, 2017, 1:00-2:00 p.m. ET Meeting Info: To check whether you have the appropriate players installed […]

  • Fri 7

    July 7 Grand Rounds: Ethics and the Precision Medicine Initiative: Reflections from Working on the CentralPMI IRB (Nancy Kass, ScD)

    Featured July 7, 2017 @ 1:00 pm - 2:00 pm

    ​Speaker: Nancy Kass, ScD Phoebe R. Berman Professor of Bioethics and Public Health Johns Hopkins Berman Institute of Bioethics Johns Hopkins Bloomberg School of Public Health Topic: Ethics and the Precision Medicine Initiative: Reflections from Working on the CentralPMI IRB Date: Friday, July 7, 2017, 1:00-2:00 p.m. ET Meeting Info: To check whether you have the appropriate players installed […]

  • Fri 28

    Grand Rounds: July 28: The DSMB Role in Pragmatic Trials: NIMH Progress and Challenges (Galia Siegel, PhD; Anna Ordonez, MD, MAS; Scott Kim, MD, PhD; Kate Comtois, PhD, MPH)

    July 28, 2017 @ 1:00 pm - 2:00 pm

    ​Speakers: Galia Siegel, PhD Clinical Trials Program Coordinator Clinical Trials Operations and Biostatistics Branch Office of Clinical Research National Institute of Mental Health, NIH Anna E. Ordóñez, MD, MAS Deputy Director Office of Clinical Research National Institute of Mental Health, NIH Scott Kim, MD, PhD Senior Investigator, Department of Bioethics Clinical Center National Institutes of […]

  • Fri 28

    Grand Rounds: July 28: The DSMB Role in Pragmatic Trials: NIMH Progress and Challenges (Galia Siegel, PhD; Anna Ordonez, MD, MAS; Scott Kim, MD, PhD; Kate Comtois, PhD, MPH)

    Featured July 28, 2017 @ 1:00 pm - 2:00 pm

    ​Speakers: Galia Siegel, PhD Clinical Trials Program Coordinator Clinical Trials Operations and Biostatistics Branch Office of Clinical Research National Institute of Mental Health, NIH Anna E. Ordóñez, MD, MAS Deputy Director Office of Clinical Research National Institute of Mental Health, NIH Scott Kim, MD, PhD Senior Investigator, Department of Bioethics Clinical Center National Institutes of […]

  • August 2017

  • Fri 11

    Grand Rounds: August 11: Embedding Clinical Trials Into Care Delivery: The Vanderbilt Experience (Gordon Bernard, MD)

    August 11, 2017 @ 1:00 pm - 2:00 pm

    ​Speaker: Gordon R. Bernard, MD Melinda Owen Bass Professor of Medicine Executive Vice President for Research Director, Vanderbilt Institute for Clinical and Translational Research Vanderbilt University Medical Center Topic: Embedding Clinical Trials Into Care Delivery: The Vanderbilt Experience Date: Friday, August 11, 2017, 1:00-2:00 p.m. ET Meeting Info: To check whether you have the appropriate players installed for […]

  • Fri 11

    Grand Rounds: August 11: Embedding Clinical Trials Into Care Delivery: The Vanderbilt Experience (Gordon Bernard, MD)

    Featured August 11, 2017 @ 1:00 pm - 2:00 pm

    ​Speaker: Gordon R. Bernard, MD Melinda Owen Bass Professor of Medicine Executive Vice President for Research Director, Vanderbilt Institute for Clinical and Translational Research Vanderbilt University Medical Center Topic: Embedding Clinical Trials Into Care Delivery: The Vanderbilt Experience Date: Friday, August 11, 2017, 1:00-2:00 p.m. ET Meeting Info: To check whether you have the appropriate players installed for […]

  • Fri 18

    Grand Rounds: August 18: Behavioral Economic Incentives in Adolescents and Young Adults: A Developmental Framework and RCT of Financial Incentives in Youth with Type 1 Diabetes (Charlene Wong, MD)

    August 18, 2017 @ 1:00 pm - 2:00 pm

    ​Speaker: Charlene Wong, MD Assistant Professor Department of Pediatrics Duke Clinical Research Institute Margolis Center for Health Policy Duke University Topic: Behavioral Economic Incentives in Adolescents and Young Adults: A Developmental Framework and RCT of Financial Incentives in Youth with Type 1 Diabetes Date: Friday, August 18, 2017, 1:00-2:00 p.m. ET Meeting Info: To check whether you have […]

  • Fri 18

    Grand Rounds: August 18: Behavioral Economic Incentives in Adolescents and Young Adults: A Developmental Framework and RCT of Financial Incentives in Youth with Type 1 Diabetes (Charlene Wong, MD)

    Featured August 18, 2017 @ 1:00 pm - 2:00 pm

    ​Speaker: Charlene Wong, MD Assistant Professor Department of Pediatrics Duke Clinical Research Institute Margolis Center for Health Policy Duke University Topic: Behavioral Economic Incentives in Adolescents and Young Adults: A Developmental Framework and RCT of Financial Incentives in Youth with Type 1 Diabetes Date: Friday, August 18, 2017, 1:00-2:00 p.m. ET Meeting Info: To check whether you have […]

  • Fri 25

    Grand Rounds August 25: Update and Thoughts from the Phenotypes, Data Standards, and Data Quality Core of the NIH HCS Research Collaboratory (Rachel Richesson, PhD, MPH)

    Featured August 25, 2017 @ 1:00 pm - 2:00 pm

    Speaker: Rachel Richesson, PhD, MPH Associate Professor Duke University School of Nursing Topic: Update and Thoughts from the Phenotypes, Data Standards, and Data Quality Core of the NIH HCS Research Collaboratory Date: Friday, August 25, 2017, 1:00-2:00 p.m. ET Meeting Info: To check whether you have the appropriate players installed for UCF (Universal Communications Format) […]

  • September 2017

  • Fri 8

    Grand Rounds September 8: Leveraging Informatics in Pragmatic Research: Initial Experience in PCORnet (Russell Rothman, MD, MPP)

    Featured September 8, 2017 @ 1:00 pm - 2:00 pm

    Speaker: Russell Rothman, MD, MPP Professor, Internal Medicine, Pediatrics, & Health Policy Vice President for Population Health Research Director, Center for Health Services Research Vanderbilt University Medical Center Topic: Leveraging Informatics in Pragmatic Research: Initial Experience in PCORnet Date: Friday, September 8, 2017, 1:00-2:00 p.m. ET Meeting Info: To check whether you have the appropriate […]

  • Fri 15

    Grand Rounds September 15, 2017: Who to Include in a Pragmatic Trial? It Depends (Greg Simon, MD; Laura Dember, MD)

    Featured September 15, 2017 @ 1:00 pm - 2:00 pm

    Speakers: Greg Simon, MD, MPH Senior Investigator Kaiser Permanente Washington Health Research Institute Laura Dember, MD Professor of Medicine University of Pennsylvania Perelman School of Medicine Topic: Who to Include in a Pragmatic Trial? It Depends Date: Friday, September 15, 2017, 1:00-2:00 p.m. ET Meeting Info: To check whether you have the appropriate players installed […]

  • Fri 22

    Grand Rounds September 22: Improving Evidence Generation for Medical Devices: The New National Evaluation System for Health Technology (NEST) (Rachael Fleurence, PhD)

    Featured September 22, 2017 @ 1:00 pm - 2:00 pm

    Speaker: Rachael Fleurence, PhD Executive Director NEST Coordinating Center Medical Device Innovation Consortium (MDIC) Topic: Improving Evidence Generation for Medical Devices: The New National Evaluation System for Health Technology (NEST) Date: Friday, September 22, 2017, 1:00-2:00 p.m. ET Meeting Info: To check whether you have the appropriate players installed for UCF (Universal Communications Format) rich […]

  • Fri 29

    Grand Rounds September 29: Preprints: What, Why Not and How (Harlan M. Krumholz, MD)

    Featured September 29, 2017 @ 1:00 pm - 2:00 pm

    Speakers: Harlan M. Krumholz, MD Harold H. Hines, Jr. Professor of Medicine Yale University School of Medicine Director, Center for Outcomes Research and Evaluation Yale-New Haven Health System Founder, Hugo Topic: Preprints: What, Why Not and How Date: Friday, September 29, 2017, 1:00-2:00 p.m. ET Meeting Info: To check whether you have the appropriate players […]

  • October 2017

  • Fri 6

    Grand Rounds October 6: Health Is More Than Healthcare (Karen B. DeSalvo, MD, MPH, MSc)

    Featured October 6, 2017 @ 1:00 pm - 2:00 pm

    Speaker: Karen DeSalvo, MD, MPH, MSc Former US HSS Acting Assistant Secretary for Health, National Coordinator for Health Information Technology Topic: Health Is More Than Healthcare Date: Friday, October 6, 2017, 1:00-2:00 p.m. ET Meeting Info: To check whether you have the appropriate players installed for UCF (Universal Communications Format) rich media files, go to […]

  • Fri 6

    Grand Rounds October 6: Health is More than Healthcare (Karen DeSalvo, PhD)

    October 6, 2017 @ 1:00 pm - 2:00 pm

    Speakers: Karen DeSalvo, PhD Topic: Health is More than Healthcare Date: Friday, October 6, 2017, 1:00-2:00 p.m. ET Meeting Info: To check whether you have the appropriate players installed for UCF (Universal Communications Format) rich media files, go to https://dukemed.webex.com/dukemed/systemdiagnosis.php. To join the online meeting: Go to https://dukemed.webex.com/dukemed/j.php?MTID=m1a4a0665a615ae0382440edecedbdd33 You must log in to the URL […]

  • Fri 13

    Grand Rounds October 13: Users’ Guide for Integrating Patient-Reported Outcomes in Electronic Health Records (Claire Snyder, PhD; Albert Wu, MD, MPH)

    Featured October 13, 2017 @ 1:00 pm - 2:00 pm

    Speakers: Claire Snyder, PhD Professor of Medicine, Oncology, and Health Policy & Management Johns Hopkins Schools of Medicine and Public Health Albert W. Wu, MD, MPH, FACP Professor and Director Center for Health Services & Outcomes Research Johns Hopkins Bloomberg School of Public Health Topic: Users’ Guide for Integrating Patient-Reported Outcomes in Electronic Health Records […]

  • Fri 20

    Grand Rounds October 20: Automated Public Health Surveillance Using Electronic Health Record Data (Michael Klompas MD, MPH, FIDSA, FSHEA)

    Featured October 20, 2017 @ 1:00 pm - 2:00 pm

    Speaker: Michael Klompas, MD, MPH, FIDSA, FSHEA Associate Professor Department of Population Medicine Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, MA Topic: Automated Public Health Surveillance Using Electronic Health Record Data Date: Friday, October 20, 2017, 1:00-2:00 p.m. ET Meeting Info: To check whether you have the appropriate players installed for UCF (Universal […]

  • November 2017

  • Fri 10

    Grand Rounds November 10: No Presentation (Veterans Day Holiday Weekend)

    November 10, 2017

    There will be no Grand Rounds presentation November 10, 2017 in observance of Veterans Day.  We hope to see you next week for "ICD-Pieces:  From Planning to Performance" by Miguel A. Vazquez, MD, and George Oliver, MD, .

  • Fri 17

    Grand Rounds November 17: ICD-Pieces: From Planning to Performance (Miguel A. Vazquez, MD; George Oliver, MD)

    Featured November 17, 2017 @ 1:00 pm - 2:00 pm

    Speakers: Miguel A. Vazquez, MD Professor of Medicine Clinical Chief Nephrology Division UT Southwestern Medical Center George Oliver, MD Vice President Clinical Informatics Parkland Center for Clinical Innovation Topic: ICD-Pieces:  From Planning to Performance Date: Friday, November 17, 2017, 1:00-2:00 p.m. ET Meeting Info: To check whether you have the appropriate players installed for UCF […]

  • Fri 24

    Grand Rounds November 24: No Presentation (Thanksgiving Holiday Weekend)

    November 24, 2017 @ 1:00 pm - 2:00 pm

    There will be no Grand Rounds presentation November 24, 2017 in observance of Thanksgiving Day.  We hope to see you next week. .  

  • December 2017

  • Fri 1

    Grand Rounds December 1: CIIC – Providing a Shared Repository of Detailed Clinical Models for all of Health and Healthcare (Stanley M. Huff, MD; W. Ed Hammond, PhD)

    Featured December 1, 2017 @ 1:00 pm - 2:00 pm

    Speakers: Stanley M. Huff, MD Chief Medical Informatics Officer Intermountain Healthcare and Professor (Clinical) of Biomedical Informatics University of Utah W. Ed Hammond, PhD Duke Center for Health Informatics Clinical & Translational Science Institute Duke University Topic: CIIC – Providing a Shared Repository of Detailed Clinical Models for all of Health and Healthcare Date: Friday, […]

  • Fri 8

    Grand Rounds December 8, 2017: Data and Safety Monitoring in Pragmatic Clinical Trials (Greg Simon, MD, MPH; Jeremy Sugarman, MD, MPH, MA; Susan Ellenberg, PhD)

    Featured December 8, 2017 @ 1:00 pm - 2:00 pm

    Speakers: Greg Simon, MD, MPH Senior Investigator Kaiser Permanente Washington Health Research Institute Jeremy Sugarman, MD, MPH, MA Harvey M. Meyerhoff Professor of Bioethics and Medicine Johns Hopkins Berman Institute of Bioethics Susan S. Ellenberg, PhD Professor of Biostatistics Professor of Medical Ethics and Health Policy Department of Biostatistics, Epidemiology and Informatics, Perelman School of […]

  • Fri 15

    Grand Rounds December 15: Does Machine Learning Have a Place in a Learning Health System? (Michael Pencina, PhD)

    Featured December 15, 2017 @ 1:00 pm - 2:00 pm

    Speaker: Michael Pencina, PhD Professor of Biostatistics and Bioinformatics, Duke University Director of Biostatistics Duke Clinical Research Institute Topic: Does machine learning have a place in a learning health system Date: Friday, December 15, 2017, 1:00-2:00 p.m. ET Meeting Info: To check whether you have the appropriate players installed for UCF (Universal Communications Format) rich […]

  • Fri 22

    Grand Rounds December 22: No Presentation (Holiday Weekend)

    December 22, 2017 @ 1:00 pm - 2:00 pm

    Grand Rounds December 22: No Presentation (Holiday Weekend) We hope to see you next week.

  • Fri 29

    Grand Rounds December 29: No Presentation (Holiday Weekend)

    December 29, 2017 @ 1:00 pm - 2:00 pm

    Grand Rounds December 29: No Presentation (Holiday Weekend) We hope to see you next week.

  • January 2018

  • Fri 5

    Grand Rounds January 5: IMPACT-AFib: An 80,000 person Randomized Trial Using the Sentinel Initiative Platform (Noelle M. Cocoros, DSc, MPH; Christopher B. Granger, MD, FACC, FAHA; Richard Platt MD, MS; Sean Pokorney, MD)

    Featured January 5, 2018 @ 1:00 pm - 2:00 pm

    Speakers: Noelle M. Cocoros, DSc, MPH Epidemiologist, Department of Population Medicine Harvard Medical School and Harvard Pilgrim Health Care Institute Christopher B. Granger, MD, FACC, FAHA Professor of Medicine, Duke University Director, Cardiac Care Unit Duke University Medical Center Richard Platt, MD, MS Professor and Chair, Department of Population Medicine Harvard Medical School and Harvard […]

  • Fri 12

    Grand Rounds January 12: Behavioral Economic Principles to Understand and Change Clinician Behavior (Jeffrey A. Linder, MD, MPH, FACP)

    Featured January 12, 2018 @ 1:00 pm - 2:00 pm

    Speaker: Jeffrey A. Linder, MD, MPH, FACP Chief, Division of General Internal Medicine and Geriatrics Michael A. Gertz Professor of Medicine Northwestern University Feinberg School of Medicine Topic: Behavioral Economic Principles to Understand and Change Clinician Behavior Date: Friday, January 12, 2018, 1:00-2:00 p.m. ET Meeting Info: To check whether you have the appropriate players […]

  • Fri 19

    Grand Rounds January 19: The Healthcare Pivot: Technology and Transformation of Healthcare (Kevin A. Schulman, MD)

    Featured January 19, 2018 @ 1:00 pm - 2:00 pm

    Speaker: Kevin A. Schulman, MD Professor of Medicine Associate Director, Duke Clinical Research Institute Visiting Scholar, Harvard Business School Topic: The Healthcare Pivot: Technology and Transformation of Healthcare Date: Friday, January 19, 2018, 1:00-2:00 p.m. ET Meeting Info: To check whether you have the appropriate players installed for UCF (Universal Communications Format) rich media files, […]

  • Fri 26

    Grand Rounds January 26: The Lumbar Imaging with Reporting of Epidemiology (LIRE) Trial: Subsequent Cross-Sectional Imaging Through 90 Days- Preliminary Results (Jeffrey Jarvik, MD, MPH; Patrick Heagerty, PhD)

    Featured January 26, 2018 @ 1:00 pm - 2:00 pm

    Speakers: Jeffrey (Jerry) G. Jarvik MD MPH Professor, Radiology, Neurological Surgery and Health Services Adjunct Professor, Pharmacy and Orthopedics & Sports Medicine Co-Director, Comparative Effectiveness, Cost and Outcomes Research Center Director, UW CLEAR Center for Musculoskeletal Disorders University of Washington Patrick J. Heagerty PhD Gilbert S. Omenn Endowed Chair in Biostatistics Professor and Chair, Department of Biostatistics University […]

  • February 2018

  • Fri 2

    Grand Rounds February 2: Early Progress on the All of Us Research Program (Joshua C. Denny, MD, MS, FACMI)

    Featured February 2, 2018 @ 1:00 pm - 2:00 pm

    Speaker: Joshua C. Denny, MD, MS, FACMI Professor of Biomedical Informatics and Medicine Director, Center for Precision Medicine Vice President for Personalized Medicine Vanderbilt University Medical Center Topic: Early Progress on the All of Us Research Program Date: Friday, February 2, 2018, 1:00-2:00 p.m. ET Meeting Info: To check whether you have the appropriate players […]

  • Fri 9

    Grand Rounds February 9: Linking Design to Analysis of Cluster Randomized Trials: Covariate Balancing Strategies (Fan Li, PhD)

    Featured February 9, 2018 @ 1:00 pm - 2:00 pm

    Speaker: Fan Li, PhD Candidate in Biostatistics Department of Biostatistics and Bioinformatics Duke University Topic: Linking Design to Analysis of Cluster Randomized Trials: Covariate Balancing Strategies Date: Friday, February 9, 2018, 1:00-2:00 p.m. ET Meeting Info: To check whether you have the appropriate players installed for UCF (Universal Communications Format) rich media files, go to https://dukemed.webex.com/dukemed/systemdiagnosis.php. […]

  • Fri 16

    Grand Rounds February 16: Considerations for the Return of Genomic Results (Heidi Rehm, PhD, FACMG; W. Andrew Faucett, MS, LGC)

    Featured February 16, 2018 @ 1:00 pm - 2:00 pm

    Speakers: Heidi Rehm, PhD, FACMG Associate Professor of Pathology Brigham & Women's Hospital and Harvard Medical School W. Andrew (Andy) Faucett, MS, LGC Professor Director of Policy and Education Office of the Chief Scientific Officer Geisinger Topic: Considerations for the Return of Genomic Results Date: Friday, February 16, 2018, 1:00-2:00 p.m. ET Meeting Info: To […]

  • Fri 23

    Grand Rounds February 23: Direct Mail Programs Work… But Will Health Centers Implement Them? Findings from STOP CRC (Gloria D. Coronado, PhD; Beverly B. Green, MD, MPH)

    Featured February 23, 2018 @ 1:00 pm - 2:00 pm

    Speakers: Gloria D. Coronado, PhD Senior Investigator Mitch Greenlick Endowed Scientist for Health Disparities Kaiser Permanente Center for Health Research Beverly B. Green, MD, MPH Associate Investigator Kaiser Permanente Washington Health Research Institute Topic: Direct Mail Programs Work… But Will Health Centers Implement Them? Findings from STOP CRC Date: Friday, February 23, 2018, 1:00-2:00 p.m. […]

  • March 2018

  • Fri 2

    Grand Rounds March 2: Distributed Research Network Querying: A Status Report (Jeff Brown, PhD; Lesley H. Curtis, PhD; Richard Platt, MD, MSc)

    Featured March 2, 2018 @ 1:00 pm - 2:00 pm

    Speakers: Jeff Brown, PhD Associate Professor, Department of Population Medicine Harvard Pilgrim Health Care Institute Lesley H. Curtis, PhD Professor of Medicine Director, Center for Population Health Sciences, Duke School of Medicine Director, Center for Pragmatic Health Systems Research, Duke Clinical Research Institute Richard Platt, MD, MS Professor and Chair, Department of Population Medicine Harvard […]

  • Tue 6

    March 6-7: Real-World Evidence Workshop Series- Workshop 2: Practical Approaches

    Featured March 6, 2018 @ 8:00 am - March 7, 2018 @ 12:30 pm

    The National Academies of Sciences, Engineering, and Medicine (National Academies) is convening the second workshop in a three-part series examining how real-world evidence development and uptake can enhance medical product development and evaluation. The workshops will advance discussions and common knowledge about complex issues relating to the generation and utilization of real-world evidence, including fostering […]

  • Wed 7

    March 7, 2018: PCORnet Best Practice Sharing Session: Lessons Learned in ADAPTABLE

    Featured March 7, 2018 @ 2:00 pm - 3:00 pm

    PCORnet Best Practice Sharing Session – Lessons Learned in ADAPTABLE: Recruitment, Retention, and Endpoint Ascertainment Join WebEx meeting: https://dukemed.webex.com/dukemed/j.php?MTID=m350d72f769538a3c056d0835692bae2a Phone: 1-650-479-3207 / Meeting Number (access code): 730 973 890 Speakers: Schuyler Jones, MD, and Holly Robertson, PhD More information on PCORnet Website: http://pcornet.org/event/pcornet-best-practice-sharing-session-lessons-learned-adaptable-recruitment-retention-endpoint-ascertainment/ All are welcome to attend! For those unable to join, the meeting […]

  • Fri 9

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    Featured March 9, 2018 @ 1:00 pm - 2:00 pm

    Speakers: Eric B. Larson, MD, MPH Vice President, Research and Health Care Innovation Kaiser Foundation Health Plan of Washington Executive Director and Senior Investigator Kaiser Permanente Washington Health Research Institute Paula Lozano, MD, MPH Associate Medical Director for Research and Translation Senior Investigator Kaiser Permanente Washington Health Research Institute Joan DeClaire Director, Communications Kaiser Permanente […]

  • Fri 16

    Grand Rounds March 16: Straight from the Source: Clinicians’ Views on Participating in CER/PCOR (Ellen Tambor, MA; Rachael Moloney, MHS; Sean Tunis, MD, MSc)

    Featured March 16, 2018 @ 1:00 pm - 2:00 pm

    Speakers: Ellen Tambor, MA Research Director Center for Medical Technology Policy (CMTP) Rachael Moloney, MHS Research Manager Center for Medical Technology Policy (CMTP) Sean Tunis, MD, MSc President and CEO Center for Medical Technology Policy (CMTP) Topic: Straight from the Source: Clinicians’ Views on Participating in CER/PCOR Date: Friday, March 16, 2018, 1:00-2:00 p.m. ET […]

  • Mon 19

    March 19: OHDSI: FDA Workshop: Developing & Submitting Proposed Draft Guidance on Patient Experience Data

    Featured March 19, 2018 @ 1:00 pm - 5:00 pm

    Topic: FDA Workshop: Developing & Submitting Proposed Draft Guidance on Patient Experience Data The purpose of this public workshop is to obtain input from stakeholders on considerations for development and submission of proposed draft guidance relating to patient experience data submitted by an external stakeholder, including: Defining the scope of the proposed draft guidance Developing […]

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