December 8, 2024: The NIH Pragmatic Trials Collaboratory hosted a workshop at AcademyHealth's 17th Annual Conference on the Science of Dissemination and Implementation in Health. The workshop introduced concepts in the design, conduct, and implementation of pragmatic clinical trials embedded in healthcare systems, with a focus on methods relevant to health services researchers.
Agenda and Slides
Morning Sessions
Welcome and Introduction
Emily O'Brien, PhD
Session 1: What Are Embedded Pragmatic Clinical Trials?
Beda Jean-Francois, PhD
Session 2: Trial Objectives and Design: An Overview of Hybrid Designs
Devon Check, PhD
Session 3: Engaging With Health System and Community Partners
Hayden Bosworth, PhD
Session 4: ePCTs in Context: Small Group Work and Panel Discussion With NIH Collaboratory Trial Investigators
Moderator: Angelo Volandes, MD, MPH
*This session includes case study presentations.
Afternoon Sessions
Session 5: Measuring Outcomes
Angelo Volandes, MD, MPH
Session 6: ePCT Design
Jonathan Moyer, PhD
Session 7: ePCT Analysis
Jonathan Moyer, PhD
Session 8: Pilot and Feasibility Testing
Beda Jean-Francois, PhD
Session 9: Ethical and Regulatory Oversight Considerations
Stephanie Morain, PhD, MPH
Session 10: Writing a Compelling Grant Application
Beda Jean-Francois, PhD
Session 11: ePCTs in Context: Small Group Work and Panel Discussion With NIH Collaboratory Trials Investigators
Moderator: Stephanie Morain, PhD, MPH
*This session includes case study presentations.
Closing Remarks
Emily O'Brien, PhD
Case Studies
Examples from the NIH Collaboratory Trials
AIM-CP: Adapting and Implementing a Nurse Care Management Model to Care for Rural Patients With Chronic Pain (Sebastian Tong, MD, MPH)
BeatPain Utah: Nonpharmacologic Pain Management in Federally Qualified Health Centers Primary Care Clinics (Julie Fritz, PhD, PT)
Chat 4 Heart Health: Using Artificially Intelligent Text Messaging Technology to Improve American Heart Association’s Life’s Essential 8 Health Behaviors (Michael Ho, MD, PhD)
NOHARM: Nonpharmacological Options in Post-operative Hospital Based and Rehabilitation Pain Management Pragmatic Trial (Andrea Cheville, MD, MSCE)
Nudge: Personalized Patient Data and Behavioral Nudges to Improve Adherence to Chronic Cardiovascular Medications (Michael Ho, MD, PhD)