Dr. Kevin Weinfurt and colleagues in the Regulatory/Ethics Core of the NIH Collaboratory recently published an article in the American Journal of Bioethics regarding how acceptable different approaches to notification and authorization are to potential participants in pragmatic research.

In a new article in eGEMs, the NIH Health Care Systems Research Collaboratory’s Patient-Reported Outcomes (PRO) Core gathered first-hand experiences on the incorporation of PROs for both care and research.

In March 2017, a new nonprofit organization was set up to support the vision and successes of PCORnet, the National Patient-Centered Clinical Research Network.

A multidisciplinary team at Johns Hopkins University has produced a draft users’ guide that focuses on best practices for integrating (PROs) in electronic health records (EHRs).

Members of the Collaboratory’s Phenotypes, Data Standards, and Data Quality Core group have published a new article describing the informatics challenges of conducting pragmatic clinical trials (PCTs) and proposing policy and research actions to facilitate the future conduct of PCTs.

​The National Academy of Medicine (NAM) has published a new discussion paper that advances the vision of a continuously learning health system, which the Institute of Medicine laid out in the 2013 report Best Care at Lower Cost: The Path to Continuously Learning Health Care in America.

Do you have a question about the rates of medical conditions or the frequency of use of medical and surgical treatments?

The National Institutes of Health’s Office of Disease Prevention (ODP) has released a free, self-paced online course on designing and analyzing pragmatic and group-randomized trials.

The Department of Health and Human Services and 15 other agencies have announced revisions to the Federal Policy for the Protection of Human Subjects, otherwise known as the Common Rule.

The NIH’s Office of Strategic Coordination is holding a live information session regarding its funding opportunity announcement (FOA) “NIH Healthcare Systems Research Collaboratory – Demonstration Projects for Pragmatic Clinical Trials (UG3/UH3).

In a recent segment on NPR’s Morning Edition, commentators discuss the potential of using electronic health records to customize medical treatments.

Research on medical practices (ROMP) includes medical record reviews, comparative effectiveness research, quality improvement interventions, and point-of-care randomization, and may improve the efficiency, quality, and cost-effectiveness of medical care. In a study by Maureen Kelly and colleagues recently published in The American Journal of Bioethics, researchers found that patients may not fully understand the rationale for ...

On June 19, 2014, the NIH Common Fund is celebrating 10 years of achievement with a symposium, A Decade of Discovery, featuring its far-reaching research. Dr. Robert Califf, principal investigator of the NIH Collaboratory Coordinating Center, will speak during the 2:15-3:15 pm session “Reengineering the Clinical Research Enterprise.” Proceedings will be streamed live throughout the ...

A series aired on American Public Media’s Marketplace program profiled real-world examples of using healthcare data to improve care and reduce costs in Camden, NJ. 1. Using data to treat the sickest and most expensive patients 2. Data: The secret ingredient in hospital cooperation 3. Data opens doors in healthcare, but then what? The first segment follows Dr. Jeffrey ...

Today, May 20th, is International Clinical Trials Day, which  marks the anniversary of what is generally believed to be one of the world’s first controlled clinical trials. In 1747, Scottish naval surgeon James Lind had undertaken what at the time constituted a daring experiment to find a treatment for scurvy, a disease caused by vitamin ...

In a commentary published this week in the journal Nature and featured in the New York Times, NIH Director Dr. Francis Collins unveiled new NIH policies that will require balanced inclusion of male and female cells and animals in NIH-funded preclinical research (with few defined exceptions). Though inclusion of women in NIH-funded clinical trials has ...

As part of its 10-year commemoration activities, the NIH Common Fund is holding a video and song competition to showcase Common Fund–supported activities in a fun and creative way. Grantees and program staff were encouraged to submit brief, original works that would be accessible and engaging to the public. The video entries have been posted, and ...