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Virtual Workshop: Endpoint Strategy in Pragmatic Trials: From Big Questions to Meaningful Outcomes (Day 1)
September 8 @ 11:00 am - 3:00 pm
The NIH Pragmatic Trials Collaboratory’s virtual workshop will share evidence and best practices in thoughtfully selecting endpoints and interpreting treatment effects in pragmatic clinical trials embedded in healthcare systems to best inform decision-making. Day 1 will focus on selecting the endpoint strategy, introduce the foundational connections between endpoints and meaningfulness, and examine endpoint complexities encountered in the design and analysis of pragmatic trials.
Day 1: September 8: 11:00 am-3:00 pm ET
- Defining the Endpoint: Where Evidence Begins
- Aiming for Impact: What is the Right Concept to Target?
- The Estimand Framework: Aligning Objectives, Endpoints, and Analyses
- Working With Multiple Outcomes: Multicomponent Endpoints and Beyond